Search results for "kl"

showing 10 items of 5772 documents

Predictive role of ankle MRI for tendon graft choice and surgical reconstruction.

2020

Purpose: Tendon transfers have become a common surgical procedure around the ankle. In this study, we sought to evaluate the existence of a correlation between specific anthropometric parameters and the size of some ankle tendons measured on MRI, in particular those mostly used as graft in ankle surgery. Methods: We recorded gender, height, weight, and body mass index (BMI) of 113 patients (57 females; mean age: 42 ± 18) who underwent ankle MRI. MRI measurements performed by a radiologist were: axial shortest diameter of Achilles (AT), posterior tibialis (PTT), flexor digitorum longus (FDLT), flexor hallucis longus (FHLT), peroneus longus (PLT), and anterior tibialis (ATT) tendons, intermal…

AdultMaleTendon TransferPatient Care Planning030218 nuclear medicine & medical imagingGraft03 medical and health sciences0302 clinical medicinePredictive Value of TestsStatistical significancePreoperative CaremedicinePeroneus longusHumansRadiology Nuclear Medicine and imagingTendon graftTendonbusiness.industryGeneral MedicineMagnetic Resonance ImagingTendonmedicine.anatomical_structure030220 oncology & carcinogenesisFlexor Digitorum LongusMann–Whitney U testSurgeryFemaleAnkleAnatomic LandmarksAnkleNuclear medicinebusinessBody mass indexLa Radiologia medica
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Investigating centre of mass stabilisation as the goal of posture and movement coordination during human whole body reaching

2000

In the light of experimental results showing significant forward centre of mass (CoM) displacements within the base of support, this study investigated if whole body reaching movements can be executed whilst keeping the CoM fixed in the horizontal axis. Using kinematic simulation techniques, angular configurations were recreated from experimental data imposing two constraints: a constant horizontal position of the CoM and an identical trajectory of the hand to grasp an object. The comparison between recorded and simulated trials showed that stabilisation of the CoM was associated with greater backward hip displacements, which became more marked with increasing object distance. This was in c…

AdultMaleTime FactorsAdolescentGeneral Computer ScienceMovementPostureKinematicsPressuremedicineHumansTorqueComputer SimulationPostural BalanceJoint (geology)SimulationMathematicsHipMovement (music)Body WeightHandGeodesyBiomechanical Phenomenamedicine.anatomical_structureTorqueHorizontal position representationTrajectoryFemaleJointsAnkleConstant (mathematics)MathematicsPsychomotor PerformanceBiotechnologyBiological Cybernetics
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Effect of cycling specialization on effort and physiological responses to uphill and flat cycling at similar intensity

2020

Power output is considered one of the best tools to control external loads in cycling, but the relationship between a target power output and the physiological responses may suffer from the effects of road gradient, which is also affected by cyclist specialization. The objective was to determine the effects of cyclist specialization on effort perception and physiological response (heart rate and lactate concentration) while sustaining efforts at similar power output but riding on two different road gradients. Nineteen male competitive road cyclists performed two randomized trials of 10 min at 0% (velodrome) and 10 min at 6% road gradient (field uphill), at an intensity of 10% ± 3% below the…

AdultMaleTime FactorsPhysical ExertionPhysical Therapy Sports Therapy and RehabilitationWorkloadWorkloadGeneral MedicinePhysiological responsesBicyclingIntensity (physics)Random AllocationYoung AdultHeart RateControl theorySpecialization (functional)HumansEnvironmental scienceOrthopedics and Sports MedicineLactic AcidPower outputCyclingSpecializationEuropean Journal of Sport Science
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Voluntary activation and mechanical performance of human triceps surae muscle after exhaustive stretch-shortening cycle jumping exercise.

2003

The purpose of this study was to examine neuromuscular factors that may contribute to post exercise force loss and subsequent recovery after exhaustive stretch-shortening cycle (SSC) exercise. Six subjects were fatigued on a sledge apparatus by 100 maximal rebound jumps followed by continuous submaximal jumping until complete exhaustion. Exercise-induced changes in neuromuscular performance were followed up to 7 days post exercise. The total number of jumps in the SSC exercise ranged from 336 to 1392. The SSC exercise induced a significant immediate plantarflexion torque decline of 29, 38 and 44% (P<0.05) in maximal voluntary contraction and evoked maximal twitch and low-frequency (LF) stim…

AdultMaleVolitionmedicine.medical_specialtySports medicinePhysiologyMovementPhysical ExertionPhysical exerciseStimulationmedicine.disease_causeStretch shortening cycleJumpingPhysical medicine and rehabilitationTriceps surae musclePhysiology (medical)ReflexmedicineHumansOrthopedics and Sports MedicineStretch reflexMuscle SkeletalExerciseMuscle fatiguebusiness.industryPublic Health Environmental and Occupational HealthGeneral MedicineAdaptation Physiologicalmedicine.anatomical_structureTorquePhysical EnduranceStress MechanicalbusinessAnkle JointPsychomotor PerformanceMuscle ContractionEuropean journal of applied physiology
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Pooled analysis of who surgical safety checklist use and mortality after emergency laparotomy

2019

Background The World Health Organization (WHO) Surgical Safety Checklist has fostered safe practice for 10 years, yet its place in emergency surgery has not been assessed on a global scale. The aim of this study was to evaluate reported checklist use in emergency settings and examine the relationship with perioperative mortality in patients who had emergency laparotomy. Methods In two multinational cohort studies, adults undergoing emergency laparotomy were compared with those having elective gastrointestinal surgery. Relationships between reported checklist use and mortality were determined using multivariable logistic regression and bootstrapped simulation. Results Of 12 296 patients incl…

AdultMalebarriershumanoschecklist; surgery; human development indexGlobalSurg CollaborativeWHO Surgical Safety Checklist mortality emergency laparotomyWorld Health Organizationseguridad del pacienteNOCohort Studieslista de controlestudios prospectivosHumanstasa de supervivenciaProspective Studiesimplementationestudios de cohortesSurgery; implementation; health; barriersEmergency Treatment11 Medical and Health Sciencesmediana edadDigestive System Surgical ProceduresAgedancianoLaparotomyScience & TechnologyhealthOriginal ArticlesadultoMiddle Agedchecklist WHOprocedimientos quirúrgicos del sistema digestivoChecklistSurvival RateElective Surgical Procedureslaparotomíatratamiento de urgenciaSurgeryOriginal ArticleFemalePatient SafetyLife Sciences & Biomedicine
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Quantification of HBG mRNA in primary erythroid cultures: prediction of the response to hydroxyurea in sickle cell and beta-thalassemia

2013

Background and Objective Increased expression of fetal hemoglobin (HbF) may ameliorate the clinical course of hemoglobinopathies like sickle cell disease (SCD) and β-thalassemia. Hydroxyurea (HU) can stimulate HbF production in these diseases but the response is highly variable indicating the utility of developing an in vitro test to predict the patient's response to HU. We assessed whether the HbF response of patients with SCD and thalassemia intermedia (TI) to HU correlates with HBG (both γ-globin genes) expression in their cultured erythroid progenitors following exposure to HU. Patients and Methods We exposed primary erythroid cultures from peripheral blood mononuclear cells from 30 pat…

AdultMalecongenital hereditary and neonatal diseases and abnormalitiesCellPrimary Cell CultureGene ExpressionAnemia Sickle CellBiologyPeripheral blood mononuclear cellhydroxyurealiquid erythroid cultureYoung AdultIn vivohemic and lymphatic diseasesFetal hemoglobinmedicineHumansgamma-GlobinsRNA MessengerFetal HemoglobinAgedErythroid Precursor CellsMessenger RNAbeta-ThalassemiaBeta thalassemiaHematologyGeneral MedicineMiddle Agedmedicine.diseaseb-thalassemiaMolecular biologyReal-time polymerase chain reactionmedicine.anatomical_structureTreatment OutcomeCell cultureFemalesickle cell disease
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In vivo fascicle behavior of the flexor hallucis longus muscle at different walking speeds.

2017

Ankle plantar flexor muscles support and propel the body in the stance phase of locomotion. Besides the triceps surae, flexor hallucis longus muscle (FHL) may also contribute to this role, but very few in vivo studies have examined FHL function during walking. Here, we investigated FHL fascicle behavior at different walking speeds. Ten healthy males walked overground at three different speeds while FHL fascicle length changes were recorded with ultrasound and muscle activity was recorded with surface electromyography (EMG). Fascicle length at heel strike at toe off and at peak EMG activity did not change with speed. Range of FHL fascicle length change (3.5-4.5 and 1.9-2.9 mm on average in s…

AdultMalehuman locomotionFast speedPhysical Therapy Sports Therapy and RehabilitationElectromyographyBiologyflexor hallucis longus mechanics03 medical and health sciencesYoung Adult0302 clinical medicinemedicineHumansOrthopedics and Sports Medicineta315Muscle Skeletalmedicine.diagnostic_testElectromyographyFootta3141Muscle bellyultrasonography030229 sport sciencesAnatomyFascicleBiomechanical PhenomenaWalking SpeedPreferred walking speedmedicine.anatomical_structureFascicle lengthFlexor hallucis longus muscleAnkleAnkle030217 neurology & neurosurgeryScandinavian journal of medicinescience in sports
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Assessment of Heart Rate Variability Thresholds from Incremental Treadmill Tests in Five Cross-Country Skiing Techniques

2016

The assessment of heart rate variability (HRV) thresholds (HRVTs) as an alternative of Ventilatory thresholds (VTs) is a relatively new approach with increasing popularity which has not been conducted in cross-country (XC) skiing yet. The main purpose of the present study was to assess HRVTs in the five main XC skiing-related techniques, double poling (DP), diagonal striding (DS), Nordic walking (NW), V1 skating (V1), and V2 skating (V2).Ten competitive skiers completed these incremental treadmill tests until exhaustion with a minimum of one to two recovery days in between each test. Ventilatory gases, HRV and poling frequencies were measured. The first HRV threshold (HRVT1) was assessed us…

AdultMalelcsh:Medicine030204 cardiovascular system & hematologyBiologyStandard deviationYoung Adult03 medical and health sciences0302 clinical medicineSkiingHeart rateStatisticsLinear regressionheart rateHumansHeart rate variabilityVagal tonelcsh:Scienceta315MultidisciplinaryTreadmill Testslcsh:Rincremental treadmill testsWorkload030229 sport sciencesExercise TestBreathingFemalelcsh:Qcross-country skiingResearch ArticlePLOS ONE
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Differences between orthopaedic evaluation and radiological reports of conventional radiographs in patients with minor trauma admitted to the emergen…

2017

Abstract Introduction During night and on weekends, in our emergency department there is no radiologist on duty or on call: thus, X-ray examinations (XR) are evaluated by the orthopaedic surgeon on duty and reported the following morning/monday by radiologists. The aim of our study was to examine the discrepancy rate between orthopaedists and radiologists in the interpretation of imaging examinations performed on patients in our tertiary level orthopaedic institution and the consequences of delayed diagnosis in terms of patient management and therapeutic strategy. Materials and methods We retrospectively reviewed all cases of discrepancy between orthopaedists and radiologists, which were ca…

AdultMalemedicine.medical_specialtyAdolescentElbowSensitivity and Specificity030218 nuclear medicine & medical imagingFractures BoneYoung Adult03 medical and health sciencesProfessional Competence0302 clinical medicinemedicineChi-square testHumansIn patientDiagnostic ErrorsChildAgedRetrospective StudiesGeneral Environmental ScienceAged 80 and overObserver Variationbusiness.industryGeneral surgery030208 emergency & critical care medicineEmergency departmentMiddle AgedSurgeryRadiographyOrthopedicsmedicine.anatomical_structureLower ExtremityMinor traumaChild PreschoolRadiological weaponOrthopedic surgeryGeneral Earth and Planetary SciencesFemaleAnkleEmergency Service HospitalbusinessInjury
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Quality of life in melanoma patients during adjuvant treatment with pegylated interferon-α2b: patients’ and doctors’ views

2011

Treatment of malignant melanoma with IFN-α has been associated with significant side-effects. The aim of this retrospective monocentric non-randomized study was first to evaluate the impact on quality of life (QOL) in 30 melanoma patients treated with once weekly 2 μg/kg PEG-IFN-α2b for 18 months, and second to examine whether there is a difference in patients' and physicians' perception of QOL. Data on QOL were collected by means of the EORTC QLQ-C30 questionnaire completed by the patient before consultation at baseline and every three months during treatment. A second questionnaire was filled out independently by the physician, based on the consultation and patient file. All data were rou…

AdultMalemedicine.medical_specialtyAdolescentEvery Three Monthsmedicine.medical_treatmentOnce weeklyDermatologyInterferon alpha-2Antiviral AgentsPolyethylene GlycolsYoung AdultAmbulatory careQuality of lifePegylated interferonHumansMedicineIn patientMelanomaAgedRetrospective StudiesAged 80 and overbusiness.industryMelanomaInterferon-alphaMiddle Agedmedicine.diseaseRecombinant ProteinshumanitiesChemotherapy AdjuvantQuality of LifePhysical therapyFemalebusinessAdjuvantmedicine.drugEuropean Journal of Dermatology
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