Search results for "kohortti"

The Individual-level Productivity Costs of Physical Inactivity

2023

Abstract Purpose: This study estimated the long-term individual-level productivity costs of physical inactivity. Methods: The data were drawn from the Northern Finland Birth Cohort 1966, to which the productivity cost variables (sick leaves and disability pensions) from Finnish registries were linked. Individuals (N = 6261) were categorized into physical activity groups based on their level of physical activity, which was measured in three ways: 1) self-reported leisure-time moderate- to vigorous-intensity physical activity (MVPA) at 46 yr old, 2) longitudinal self-reported leisure-time MVPA at 31–46 yr old, and 3) accelerometer-measured overall MVPA at 46 yr old. The human capital approach…

Entisten suomalaisten huippu-urheilijoiden alkoholinkäyttö ja alkoholisairauksien riski

2016

Kontro, T. 2016. Entisten suomalaisten huippu-urheilijoiden alkoholinkäyttö ja alkoholisairauksien riski. Terveystieteiden laitos, Jyväskylän yliopisto, liikuntalääketieteen pro gradu -tutkielma, 69 s., 7 liitettä. Tutkimuksen tausta ja tarkoitus: Haitallinen alkoholinkäyttö on globaali ongelma. Myös entisten huippu-urheilijoiden alkoholinkäytöstä on keskusteltu mediassa paljon, mutta tieteellistä näyttöä aiheesta ei juurikaan ole olemassa. Tämän tutkimuksen tarkoituksena oli tutkia aiemman kilpaurheilu-uran ja alkoholisairauksien välistä yhteyttä sekä alkoholinkäyttöä eri urheilulajiryhmissä ja verrokeilla. Lisäksi haluttiin selvittää eri taustamuuttujien, kuten kilpa- ja kuntourheiluaktiv…

Serum Albumin and Future Risk of Hip, Humeral, and Wrist Fractures in Caucasian Men : New Findings from a Prospective Cohort Study

2019

Objective: Low serum albumin concentration is associated with poor health outcomes, but its relationship with the risk of fractures has not been reliably quantified. We aimed to assess the prospective association of serum albumin with the risk of fractures in a general population. Subjects and Methods: Baseline serum albumin concentrations were measured in 2,245 men aged 42–61 years in the Kuopio Is­chemic Heart Disease study. Hazard ratios (HRs) (95% confidence intervals) were calculated for incident fractures. Results: A total of 121 fractures (hip, humeral, or wrist) were recorded during a median follow-up of 25.6 years. The risk of fractures increased linearly below a serum albumin conc…

Need adapted use of medication in the open dialogue approach for psychosis : a descriptive longitudinal cohort study

2022

Background The open dialogue (OD) approach includes the need-adapted use of psychiatric medication in treating first-episode psychosis (FEP), but there is limited information on how psychiatric medications are actually used in OD-based services. This study aims to analyse long-term medication dispensing patterns among FEP cohort treated according to the OD. Methods The OD cohort consisted of people who received treatment for FEP in the Finnish Western Lapland catchment area at a time of OD implementation (n=61). The comparison group included people whose FEP treatment commenced outside the catchment area during the mid-1990s (n=1378). Data were gathered from national registers from onset to…

The 10‐year treatment outcome of open dialogue‐based psychiatric services for adolescents: A nationwide longitudinal register‐based study

2022

Aim: To evaluate the 10-year treatment outcomes and cost-effectiveness of adolescents' mental health treatment initiated under the social network-oriented open dialogue (OD) approach. -- Methods: This longitudinal register-based study included all persons who, for the first time, received psychiatric treatment in Finland during the period 1 January 2003–31 December 2008, and who were aged 13–20 at onset (n = 44 868). The OD group included all persons whose treatment commenced in the Western Lapland catchment area (n = 780), this being the only region in Finland where OD covered the entire mental healthcare service at the time of inclusion. The comparison group (CG) included the rest of Finl…

Adiposity-Related Predictors of Vascular Aging From a Life Course Perspective : Findings From the Helsinki Birth Cohort Study

2022

Menopause modulates the circulating metabolome: evidence from a prospective cohort study

2022

Abstract Aims We studied the changes in the circulating metabolome and their relation to the menopausal hormonal shift in 17β-oestradiol and follicle-stimulating hormone levels among women transitioning from perimenopause to early postmenopause. Methods and results We analysed longitudinal data from 218 Finnish women, 35 of whom started menopausal hormone therapy during the study. The menopausal transition was monitored with menstrual diaries and serum hormone measurements. The median follow-up was 14 months (interquartile range: 8–20). Serum metabolites were quantified with targeted nuclear magnetic resonance metabolomics. The model results were adjusted for age, follow-up duration, educat…

FinnTwin16 : A Longitudinal Study from Age 16 of a Population-Based Finnish Twin Cohort

2019

The purpose of this review is to provide a detailed and updated description of the FinnTwin16 (FT16) study and its future directions. The Finnish Twin Cohort comprises three different cohorts: the Older Twin Cohort established in the 1970s and the FinnTwin12 and FT16 initiated in the 1990s. FT16 was initiated in 1991 to identify the genetic and environmental precursors of alcoholism, but later the scope of the project expanded to studying the determinants of various health-related behaviors and diseases in different stages of life. The main areas addressed are alcohol use and its consequences, smoking, physical activity, overall physical health, eating behaviors and eating disorders, weight…

Sustainable Working Life Patterns in a Swedish Twin Cohort : Age-Related Sequences of Sickness Absence, Disability Pension, Unemployment, and Prematu…

2022

We aimed to investigate sustainable working life via age-related sequences of sickness absence (SA), disability pension (DP), unemployment (UE), premature death, and the influence of individual characteristics, accounting for familial confounding. The sample included monozygotic (MZ) and dizygotic (DZ) same-sexed twin pairs with register data (n = 47,450) that were followed for 10 years in four age cohorts: 26–35 (n = 9892), 36–45 (n = 10,620), 46–55 (n = 12,964) and 56–65 (n = 13,974). A sequence analysis was done in a 7-element state space: 1. “Sustainable working life”: SA/DP 0–30 days and UE 0–90 days; 2. “Unemployment >90 days”: SA/DP 0–30 days and UE > 90 days; 3. “Moderate SA/DP”: SA…

Liikuntaharrastus iäkkäänä - kohortti- ja seuruututkimus iäkkäiden liikunnasta

2011

Tämän tutkimuksen tarkoituksena oli selvittää ikääntyvien yli 65-vuotiaiden henkilöiden liikun-nan harrastamista ja siinä tapahtuvia muutoksia kohortti- ja seuruututkimuksen avulla. Lisäksi tarkasteltiin sosiaalisen ja fyysisen lähiympäristön yhteyttä iäkkäiden henkilöiden fyysiseen ak-tiivisuuteen ja liikuntaharrastukseen. Tutkimus on osa Jyväskylässä vuosina 1988–2004 toteutet-tua Ikivihreät – projektia. Aineisto kerättiin strukturoidulla haastattelulla. Kohorttihaastatteluihin osallistui 80 % (n=362) 65–69-vuotiasta jyväskyläläistä vuonna 1988, 79 % (n=320) vuonna 1996 ja 73 % (n=292) vuonna 2004. Seuruuaineisto kerättiin vuonna 1988 vuosina 1914–23 syntyneiltä kotona asuvilta jyväskyläl…