Search results for "kohorttitutkimus"

Dementia in former amateur and professional contact sports participants : population-based cohort study, systematic review, and meta-analysis

2023

Background Although there is growing evidence that former professional athletes from sports characterised by repetitive head impact subsequently experience an elevated risk of dementia, the occurrence of this disorder in retired amateurs, who represent a larger population, is uncertain. The present meta-analysis integrates new results from individual-participant analyses of a cohort study of former amateur contact sports participants into a systematic review of existing studies of retired professionals and amateurs. Methods The cohort study comprised 2005 male retired amateur athletes who had competed internationally for Finland (1920–1965) and a general population comparison group of 1386 …

Physical activity may not be associated with long‐term risk of dementia and Alzheimer’s disease

2021

Background While it is well established that physical activity is associated with reduced risk of vascular and non‐vascular outcomes as well as mortality, evidence on the association between physical activity and dementia is inconsistent. We aimed to assess the associations of physical activity with the risk of dementia and Alzheimer’s disease (AD). Material and methods We analysed data on 2,394 apparently healthy men with good baseline cognitive function from the prospective population‐based Kuopio Ischaemic Heart Disease study. We assessed habits of physical activity at baseline using a 12‐month leisure‐time physical activity (LTPA) questionnaire. Using Cox regression, we calculated hazar…

Self-reported life-space mobility in the first year after ischemic stroke: longitudinal findings from the MOBITEC-Stroke project

2023

Abstract Background Life-space mobility is defined as the size of the area in which a person moves about within a specified period of time. Our study aimed to characterize life-space mobility, identify factors associated with its course, and detect typical trajectories in the first year after ischemic stroke. Methods MOBITEC-Stroke (ISRCTN85999967; 13/08/2020) was a cohort study with assessments performed 3, 6, 9 and 12 months after stroke onset. We applied linear mixed effects models (LMMs) with life-space mobility (Life-Space Assessment; LSA) as outcome and time point, sex, age, pre-stroke mobility limitation, stroke severity (National Institutes of Health Stroke Scale; NIHSS), modified R…

Changes in physical performance according to job demands across three cohorts of older workers in the Longitudinal Aging Study Amsterdam

2023

This study set out to evaluate the association between job demands at baseline and physical performance over a six-year period across three cohorts of older Dutch workers examined 10 years apart. Data were drawn from three cohorts (1992–1999, 2002–2009 and 2012–2019) of the Longitudinal Aging Study Amsterdam. Individuals aged 55–65 years from each cohort who worked for pay were included (n = 274, n = 416, n = 618, respectively). Physical performance was measured using gait speed and chair stand performance. A population-based job exposure matrix was used to indicate levels of exposure probability of physical (use of force and repetitive movements) and psychosocial (cognitive demands and tim…

Association of accelerometer‐measured physical activity and midlife income : A Northern Finland Birth Cohort 1966 Study

2023

This study investigated the association between physical activity (PA) and midlife income. The population-based data comprised employed members of the Northern Finland Birth Cohort 1966 (N = 2797). Using binned scatterplots and polynomial regressions, we evaluated the association between accelerometer-measured moderate PA (MPA), vigorous PA (VPA), and moderate-to-vigorous PA (MVPA) at 46 years old and register-based income at 50 years old. The models were adjusted for sex, marital status, number of children, education, adolescent PA, occupational physical strenuousness, and time preference. We found MPA (p < 0.001), VPA (p < 0.05), and MVPA (p < 0.001) to associate curvilinearly with income…

Low back disorders in the long term among employees in the engineering industry : a study with 5-, 10- and 28-year follow-ups

2010

Walking, physical activity and life-space mobility among older people

2017

Autonomy in mobility is a central component of active ageing. Life-space mobility describes where, when, and how an individual reaches desired destinations. Walking, an important form of physical activity among older people, is a prerequisite for engaging in daily activities. This study explored the cross-sectional and longitudinal relationships between physical activity and life-space mobility. The associations of walking with reasons for going outdoors in different life-space areas, living arrangements, and environmental barriers to mobility were also examined. Data from two larger studies were used: the Life-Space Mobility in Old Age (LISPE) accelerometer substudy (n=174, median age 79.7…

Longitudinal physical activity patterns and the development of cardiometabolic risk factors during adolescence

2023

Purpose To examine the associations between longitudinal physical activity (PA) patterns and the development of cardiometabolic risk factors from adolescence to young adulthood. Methods This cohort study encompassed 250 participants recruited from sports clubs and schools, and examined at mean age 15 and 19. Device-measured moderate-to-vigorous PA was grouped into five patterns (via a data-driven method, using inactivity maintainers as a reference). The outcomes were: glucose, insulin, homeostasis model assessment for insulin resistance (HOMA-IR), total cholesterol, HDL and LDL cholesterol, triglycerides, blood pressure, and body mass index (BMI). Linear growth curve models were applied wit…