Search results for "koronavirukset"
showing 5 items of 5 documents
Serological Follow-Up Study Indicates High Seasonal Coronavirus Infection and Reinfection Rates in Early Childhood
2022
Seasonal human coronaviruses (HCoVs) cause respiratory infections, especially in children. Currently, the knowledge on early childhood seasonal coronavirus infections and the duration of antibody levels following the first infections is limited. Here we analyzed serological follow-up samples to estimate the rate of primary infection and reinfection(s) caused by seasonal coronaviruses in early childhood. Serum specimens were collected from 140 children at ages of 13, 24, and 36 months (1, 2, and 3 years), and IgG antibody levels against recombinant HCoV nucleoproteins (N) were measured by enzyme immunoassay (EIA). Altogether, 84% (118/140) of the children were seropositive for at least one s…
Computational approach to design of aptamers to the receptor binding domain of SARS-CoV-2
2021
The aim of the research. In this work, in silico selection of DNA-aptamers to the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein was performed using molecular modeling methods. Material and methods. A new computational approach to aptamer in silico selection is based on a cycle of simulations, including the stages of molecular modeling, molecular docking, molecular dynamic simulations, and quantum chemical calculations. To verify the obtained calculated results flow cytometry, fluorescence polarization, and small-angle X-ray scattering methods were applied. Results. An initial library consisted of 256 16-mer oligonucleotides was modeled. Based on molecular docking results, th…
Kulutus koronan aikaan - ja sen jälkeen : tutkimus COVID-19-epidemian rajoitustoimien vaikutuksesta kuluttajien käyttäytymiseen, taloudelliseen toimi…
2020
Tässä kyselytutkimuksessa (N=1000) selvitettiin koronavirusepidemiasta johtuvien rajoitusten vaikutusta työikäisten (18-65 vuotta) suomalaisten kuluttajien käyttäytymiseen arjessa sekä koronarajoitusten vaikutusta heidän taloudelliseen tilanteeseensa ja koettuun hyvinvointiin. Lisäksi tutkittiin kuluttajien arviota kulutuksesta rajoitusten purkaannuttua. Tutkimustuloksista käy ilmi, että valtaosa vastaajista koki koronarajoitukset tarpeellisiksi. Vain harvat ajattelivat, että arkea rajoittavista määräyksistä, kuten kauppojen ja palvelujen aukiolojen rajoituksista tai liikkumisrajoituksista oli suurta haittaa. Miehet kokivat haittoja naisia yleisemmin. Liikkumis- ja matkustusrajoitukset hait…
Artificial intelligence centric scientific research on COVID-19 : an analysis based on scientometrics data
2023
AbstractWith the spread of the deadly coronavirus disease throughout the geographies of the globe, expertise from every field has been sought to fight the impact of the virus. The use of Artificial Intelligence (AI), especially, has been the center of attention due to its capability to produce trustworthy results in a reasonable time. As a result, AI centric based research on coronavirus (or COVID-19) has been receiving growing attention from different domains ranging from medicine, virology, and psychiatry etc. We present this comprehensive study that closely monitors the impact of the pandemic on global research activities related exclusively to AI. In this article, we produce highly info…
Microstructural evaluation and recommendations for face masks in community use to reduce the transmission of respiratory infectious diseases
2022
Funding Information: A.K., H.Y. and R.J. also acknowledges the funding through Academy of Finland BESIMAL (Decision No. 334197) and Aalto University, Department of Communications and Networking. This work has also received funding in part from the EPSRC UK (grant number EP/R012091/1). A.K. would also like to thank Mr. Volkan Kaplan for the fruitful discussions in the early concept generation. Publisher Copyright: © 2022 The Author(s) Background and Objective: Recommendations for the use of face masks to prevent and protect against the aerosols (≤5µm) and respiratory droplet particles (≥5µm), which can carry and transmit respiratory infections including severe acute respiratory syndrome coro…