Search results for "laboratory"

Differential modulation and prognostic values of immune-escape genes in uveal melanoma

2019

Uveal melanoma (UM) is the most common primary intraocular cancer in adults. In the present study, we aimed to characterize the immunological features of primary UM cancer and to provide an association with prognostic markers and outcome. Also, we assessed the influence of the microenvironment on the expression of inhibitory immune checkpoints in UM. Genes of interest included MHC Class I and Class II molecules, as well as inhibitory immune-checkpoints, i.e. PDL1, PDL2, B7-H3, B7-H4, TBFRSF6B, CD47, CD155, GAL9, HVEM and CD200. We observed significant lower levels of MHC genes in UM cells as compared to normal uveal melanocytes. Unexpectedly however, the expression levels of most of the ana…

Scaling carbon fluxes from eddy covariance sites to globe: synthesis and evaluation of the FLUXCOM approach

2020

FLUXNET comprises globally distributed eddy-covariance-based estimates of carbon fluxes between the biosphere and the atmosphere. Since eddy covariance flux towers have a relatively small footprint and are distributed unevenly across the world, upscaling the observations is necessary to obtain global-scale estimates of biosphere–atmosphere exchange. Based on cross-consistency checks with atmospheric inversions, sun-induced fluorescence (SIF) and dynamic global vegetation models (DGVMs), here we provide a systematic assessment of the latest upscaling efforts for gross primary production (GPP) and net ecosystem exchange (NEE) of the FLUXCOM initiative, where different machine learning methods…

Spectrodirectional Minnaert-kretrieval using CHRIS-PROBA data

2010

We report on a detailed analysis of hyperspectral and multidirectional remote sensing data acquired using the Compact High Resolution Imaging Spectrometer (CHRIS) mounted onboard the Project for On-Board Autonomy (PROBA) spacecraft. This instrument is capable of sampling reflected radiation over the visible and near-infrared (NIR) region of the solar spectrum at a spatial resolution (approx. 17 m) intermediary between sensors traditionally used in land applications (such as Landsat and Satellite Pour l’Observation de la Terre (SPOT), 30 m–50 m) and the latest instruments delivering a nominal resolution of 1 m or less. The spectral anisotropic signature of an Alpine coniferous forest during …

Experimental Analysis of Horizontal Turbulence of Flow over Flat and Deformed Beds

2015

Abstract Laboratory experiments in a straight flume were carried out to examine the evolution of large-scale horizontal turbulent structures under flat-bed and deformed-bed conditions. In this paper, the horizontal turbulence of flow under these conditions is analyzed and compared. The conditioned quadrant method is applied to verify the occurrence of turbulent events. The distributions of horizontal Reynolds shear stress and turbulent kinetic energy are also presented and discussed. Results show the occurrence of an “initial” sequence of horizontal vortices whose average spatial length scales with the channel width. Under deformed-bed conditions, this spatial length does not change.

Patented and commercialized applications

2021

Abstract The commercialization of high added-value compounds recovery from food wastes deals with several issues such as laboratory research, scale-up problems, protection of intellectual properties, and development of market-destined applications. These issues are described in this chapter wherein a collection of commercially available compounds recovered from food by-products is presented. Verification of market existing products matching with patented processes was conducted using patent applicant name in each case. However, this matching as well as production characteristics may not be correct in all cases, as most companies typically are secretive about their methods of production and …

Zeeman effect in sulfur monoxide: A tool to probe magnetic fields in star forming regions

2017

[Context] Magnetic fields play a fundamental role in star formation processes and the best method to evaluate their intensity is to measure the Zeeman effect of atomic and molecular lines. However, a direct measurement of the Zeeman spectral pattern from interstellar molecular species is challenging due to the high sensitivity and high spectral resolution required. So far, the Zeeman effect has been detected unambiguously in star forming regions for very few non-masing species, such as OH and CN.

1919. gada Mečislava Centneršvēra veidotais ķīmijas praktikums

2019

Raksts par Latvijas Universitātes Muzeja krājumā esošo poļu fizikālķīmiķa Mečislava Centneršvēra (1874-1944) 1919. gadā veidoto ķīmijas praktikumu inženieriem, mehāniķiem un arhitektiem.

COVID-19 infodemics: the role of mainstream and social media

2021

Performance of the QuantiFERON-cytomegalovirus (CMV) assay for detection and estimation of the magnitude and functionality of the CMV-specific gamma …

2012

ABSTRACTThe performance of the QuantiFERON-cytomegalovirus (CMV) assay was compared to that of a flow cytometry intracellular cytokine staining (ICS) method for the detection of CMV-specific gamma interferon (IFN-γ)-producing CD8+T-cell responses in allogeneic stem cell transplant (allo-SCT) recipients and for estimations of their magnitude and functionality. A total of 90 whole-blood specimens from 23 allo-SCT recipients was analyzed by both methods. Overall, the percentage of specimens that yielded concordant results by both methods was 68.8% (κ = 0.691; 95% confidence interval [CI], 0.548 to 0.835), and the sensitivity of the QuantiFERON-CMV assay for the detection of positive IFN-γ T-ce…

Epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole for six Candida species as determined by the colorimetric…

2013

ABSTRACT In the absence of clinical breakpoints (CBP), epidemiological cutoff values (ECVs) are useful to separate wild-type (WT) isolates (without mechanisms of resistance) from non-WT isolates (those that can harbor some resistance mechanisms), which is the goal of susceptibility tests. Sensititre YeastOne (SYO) is a widely used method to determine susceptibility of Candida spp. to antifungal agents. The CLSI CBP have been established, but not for the SYO method. The ECVs for four azoles, obtained using MIC distributions determined by the SYO method, were calculated via five methods (three statistical methods and based on the MIC 50 and modal MIC). Respectively, the median ECVs (in mg/lit…