Search results for "landmark"

showing 10 items of 44 documents

Boosting Signal-to-Noise in Complex Biology: Prior Knowledge Is Power

2011

A major difficulty in the analysis of complex biological systems is dealing with the low signal-to-noise inherent to nearly all large biological datasets. We discuss powerful bioinformatic concepts for boosting signal-to-noise through external knowledge incorporated in processing units we call filters and integrators. These concepts are illustrated in four landmark studies that have provided model implementations of filters, integrators, or both.

0303 health sciencesLandmarkBoosting (machine learning)Biochemistry Genetics and Molecular Biology(all)business.industryBiologyMachine learningcomputer.software_genreBioinformaticsGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicine030220 oncology & carcinogenesisIntegratorArtificial intelligencebusinesscomputerImplementation030304 developmental biologyCell
researchProduct

Automatic detection and classification of retinal vascular landmarks

2014

The main contribution of this paper is introducing a method to distinguish between different landmarks of the retina: bifurcations and crossings. The methodology may help in differentiating between arteries and veins and is useful in identifying diseases and other special pathologies, too. The method does not need any special skills, thus it can be assimilated to an automatic way for pinpointing landmarks; moreover it gives good responses for very small vessels. A skeletonized representation, taken out from the segmented binary image (obtained through a preprocessing step), is used to identify pixels with three or more neighbors. Then, the junction points are classified into bifurcations or…

Acoustics and UltrasonicsComputer scienceMaterials Science (miscellaneous)General MathematicsPreprocessorRadiology Nuclear Medicine and imagingComputer visionretinal vessel landmark points retinal vessel structure classificationRepresentation (mathematics)Instrumentationlcsh:R5-920PixelSettore INF/01 - Informaticabusiness.industryBinary imagelcsh:Mathematicslcsh:QA1-939retinal vessel structure classificationSignal ProcessingComputer Vision and Pattern RecognitionArtificial intelligencebusinessPrecision and recallretinal vessel landmark pointslcsh:Medicine (General)Biotechnology
researchProduct

A new Infraclavicular Landmark-Based Approach to the Axillary Vein as an Alternative Method of Central Venous Cannulation

2016

Purpose: We developed the new technique of the axillary vein catheterization, which is connected with the determination of only two anatomical points of reference for puncture site identification. The primary outcome of this study was to determine the rate of successful catheterizations and the assessment of procedure success rate, depending on cannulation side as well as physician experience. The secondary objective was to evaluate the early complication rate and to determine whether this method can be used in clinical practice. Methods: The methodology of this prospective, cohort study included catheterization of the axillary vein via the infraclavicular approach. All procedures were perf…

AdultMaleCatheterization Central Venousmedicine.medical_specialtyTime FactorsTreatment outcomePunctures030204 cardiovascular system & hematologyCatheterizationYoung Adult03 medical and health sciencesCatheters Indwelling0302 clinical medicineRisk FactorsIntensive careCatheterization PeripheralmedicineCentral Venous CathetersHumansProspective StudiesProspective cohort studyAgedAged 80 and overAlternative methodsLandmarkbusiness.industryAxillary vein030208 emergency & critical care medicineMiddle AgedSurgeryTreatment OutcomeNephrologyIntensive careFemaleSurgeryClinical CompetenceRadiologyAnatomic LandmarksClinical competencebusinessAxillary veinLearning CurveVenous cannulationThe Journal of Vascular Access
researchProduct

Orthodontic camouflage versus orthognathic surgery for class III deformity: comparative cephalometric analysis

2017

The objective of this study was to compare different cephalometric variables in adult patients with class III malocclusions before and after treatment, in order to determine which variables are indicative of orthodontic camouflage or orthognathic surgery. The cases of 156 adult patients were assessed: 77 treated with orthodontic camouflage and 79 treated with orthodontics and orthognathic surgery. The following cephalometric variables were measured on pre-treatment (T1) and post-treatment (T2) lateral cephalograms: sella-nasion-A-point (SNA), sella-nasion-B-point (SNB), and A-point-nasion-B-point (ANB) angles, Wits appraisal, facial axis angle, mandibular plane angle, upper and lower inciso…

AdultMaleCephalometric analysisCephalometrymedicine.medical_treatmentOrthognathic surgeryDentistryClass iiiOrthodontics Corrective03 medical and health sciences0302 clinical medicine0502 economics and businessmedicineDeformityHumansOrthodonticsAdult patientsOrthognathic Surgical ProceduresFacial axisbusiness.industry05 social sciencesLateral cephalograms030206 dentistryCross-Sectional StudiesMalocclusion Angle Class IIITreatment OutcomeOtorhinolaryngologyFemale050211 marketingSurgeryMandibular plane angleAnatomic LandmarksOral Surgerymedicine.symptombusinessInternational Journal of Oral and Maxillofacial Surgery
researchProduct

Influence of skeletal class in the morphology of cervical vertebrae: A study using cone beam computed tomography

2016

ABSTRACT Objectives: To quantify the prevalence of cervical vertebrae anomalies and to analyze any association between them and skeletal malocclusions or head posture positions in the same study. Materials and Methods: Two hundred forty patients who were attending the Department of Orthodontics of the University of Valencia for orthodontic treatment were selected and divided into three groups: skeletal Class I (control group, 0° <ANB < 4°), Class II (ANB ≥ 4°), and Class III (ANB ≤ 0°) according to ANB Steiner angle. The morphology of the first five cervical vertebrae was analyzed with cone beam computed tomography to identify any anomalies. Intra- and interobserver error meth…

AdultMaleCone beam computed tomographyCephalometryDentistryOrthodonticsMalocclusion Angle Class IMandibleDehiscenceMalocclusion Angle Class IIStatistics Nonparametric03 medical and health sciences0302 clinical medicineIncisormedicineMaxillaHumansOrthodonticsbusiness.industry030206 dentistryOriginal ArticlesCraniometryCone-Beam Computed TomographySkeletal classmedicine.diseaseIncisormedicine.anatomical_structureMalocclusion Angle Class IIIMaxillaCervical VertebraeFemaleMalocclusionAnatomic LandmarksbusinessHead030217 neurology & neurosurgeryMalocclusionCervical vertebrae
researchProduct

Chemotherapy-induced neutropenia and treatment efficacy in advanced non-small-cell lung cancer: a pooled analysis of three randomised trials

2005

Summary Background Chemotherapy is the standard treatment for advanced non-small-cell lung cancer, and myelosuppression is a common side-effect. We aimed to assess whether haematological toxic effects could be a biological measure of drug activity and a marker of efficacy. Methods We analysed data for 1265 patients who received chemotherapy (vinorelbine, gemcitabine, gemcitabine and vinorelbine, cisplatin and vinorelbine, or cisplatin and gemcitabine) within three randomised trials. Primary landmark analyses were restricted to 436 patients who received all six planned chemotherapy cycles and who were alive 180 days after randomisation. Neutropenia was categorised on the basis of worst WHO g…

AdultMaleOncologymedicine.medical_specialtyLung NeoplasmsNeutropeniamedicine.medical_treatmentAntineoplastic AgentsNeutropenia.VinorelbineSeverity of Illness IndexCarcinoma Non-Small-Cell LungInternal medicinemedicineHumansLung cancerSurvival rateAgedProportional Hazards ModelsRandomized Controlled Trials as TopicAged 80 and overChemotherapyDose-Response Relationship Drugbusiness.industryStandard treatmentHazard ratioMiddle Agedrandomized clinical trialmedicine.diseaseGemcitabineSurgerySurvival Ratelandmark analysisnon-small-cell lung cancerItalyOncologychemotherapy-induced neutropeniaFemaleDrug MonitoringbusinessBiomarkersmedicine.drug
researchProduct

A comparative study of the pharyngeal airway space, measured with cone beam computed tomography, between patients with different craniofacial morphol…

2014

Abstract Purpose The present study aims to determine any existing association between airway dimensions, measured with cone beam computed tomography (CBCT), and the different patient craniofacial morphologies. Material and methods Sixty CBCT (Dental Picasso Master 3D) images, from patients treated at the Orthodontics Master at Valencia University were selected. The program InVivoDental 5.1 was used to visualize sections, analyze three-dimensional images, and perform airway measurements in the three planes of the space. Intra- and interobserver error methods were recorded. After that, measurements at three different levels of the airway (upper, medium, lower) were taken, in both the anteropo…

AdultMalePalate HardCone beam computed tomographyAdolescentClass iiiMalocclusion Angle Class IMandibleMalocclusion Angle Class IIYoung AdultImaging Three-DimensionalImage Processing Computer-AssistedMedicineHumansCraniofacialChildSkull Basebusiness.industryHyoid BoneReproducibility of ResultsVertical DimensionAnatomyrespiratory systemCone-Beam Computed TomographyCross-Sectional StudiesMalocclusion Angle Class IIIOtorhinolaryngologyPharynxSurgeryFemaleOral SurgeryAnatomic LandmarksPalate SoftbusinessAirwayMalocclusionJournal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
researchProduct

Shape change in the atlas with congenital midline non-union of its posterior arch: a morphometric geometric study.

2017

Background Context The congenital midline non-union of the posterior arch of the atlas is a developmental variant present at a frequency ranging from 0.7% to 3.9%. Most of the reported cases correspond to incidental findings during routine medical examination. In cases of posterior non-union, hypertrophy of the anterior arch and cortical bone thickening of the posterior arches have been observed and interpreted as adaptive responses of the atlas to increased mechanical stress. Purpose We sought to determine if the congenital non-union of the posterior arch results in a change in the shape of the atlas. Study Design/Setting This study is an analysis of the first cervical vertebrae from osteo…

AdultMaleShape change03 medical and health sciencesLandmarkYoung Adult0302 clinical medicineImaging Three-DimensionalAtlas (anatomy)Congenital non-unionmedicineSuperimpositionHumansOrthopedics and Sports Medicine030212 general & internal medicinePosterior archArchCervical AtlasAgedAged 80 and overGeometric morphometricsbusiness.industryAnatomyMiddle AgedPosterior archSemilandmarkVertebramedicine.anatomical_structureShape changeSurgeryCortical boneFemaleNeurology (clinical)AtlasbusinessTomography X-Ray Computed030217 neurology & neurosurgeryCervical vertebraeThe spine journal : official journal of the North American Spine Society
researchProduct

Predictive role of ankle MRI for tendon graft choice and surgical reconstruction.

2020

Purpose: Tendon transfers have become a common surgical procedure around the ankle. In this study, we sought to evaluate the existence of a correlation between specific anthropometric parameters and the size of some ankle tendons measured on MRI, in particular those mostly used as graft in ankle surgery. Methods: We recorded gender, height, weight, and body mass index (BMI) of 113 patients (57 females; mean age: 42 ± 18) who underwent ankle MRI. MRI measurements performed by a radiologist were: axial shortest diameter of Achilles (AT), posterior tibialis (PTT), flexor digitorum longus (FDLT), flexor hallucis longus (FHLT), peroneus longus (PLT), and anterior tibialis (ATT) tendons, intermal…

AdultMaleTendon TransferPatient Care Planning030218 nuclear medicine & medical imagingGraft03 medical and health sciences0302 clinical medicinePredictive Value of TestsStatistical significancePreoperative CaremedicinePeroneus longusHumansRadiology Nuclear Medicine and imagingTendon graftTendonbusiness.industryGeneral MedicineMagnetic Resonance ImagingTendonmedicine.anatomical_structure030220 oncology & carcinogenesisFlexor Digitorum LongusMann–Whitney U testSurgeryFemaleAnkleAnatomic LandmarksAnkleNuclear medicinebusinessBody mass indexLa Radiologia medica
researchProduct

Visuospatial processing in schizophrenia: Does it share common mechanisms with pseudoneglect?

2011

International audience; ''Schizophrenia patients demonstrate behavioural and cerebral lateralised anomalies, prompting some authors to suggest they exhibit a mild form of right unilateral neglect. To better describe and understand lateralised visuospatial anomalies in schizophrenia, three experiments were run using tasks often utilised to study visuospatial processing in healthy individuals and in neglect patients: the Behavioural Inattention Test (BIT), the manual line bisection task with and without a local cueing paradigm, the landmark task (or line bisection judgement), and the number bisection task. Although the schizophrenia patients did not exhibit the full-blown neglect syndrome, th…

AdultMaleendocrine systemSchizophrenia (object-oriented programming)Behavioural inattention testBisectionmedia_common.quotation_subjectSPATIAL ATTENTIONMENTAL NUMBER LINEHANDbehavioral disciplines and activities050105 experimental psychologyTask (project management)NeglectPerceptual DisordersBRAIN-DAMAGEYoung Adult03 medical and health sciencesLANDMARK TASK0302 clinical medicineArts and Humanities (miscellaneous)PerceptionHumans0501 psychology and cognitive sciencesMild formGeneral Psychologymedia_common[SCCO.NEUR]Cognitive science/Neuroscience05 social sciencesGeneral MedicinePERFORMANCEUNILATERAL NEGLECT''MENTAL NUMBER LINEHEMISPATIAL NEGLECTHAND''Unilateral neglectSpace Perception[ SCCO.NEUR ] Cognitive science/NeuroscienceSchizophreniaVisual PerceptionFemaleSchizophrenic PsychologyHEMISPHERIC-ASYMMETRYPsychologyPhotic StimulationBISECTION JUDGMENTSpsychological phenomena and processes030217 neurology & neurosurgeryCognitive psychologyLaterality: Asymmetries of Body, Brain and Cognition
researchProduct