Search results for "lasi"

showing 10 items of 1298 documents

A case of atypical sporadic hemiplegic migraine associated with PFO and hypoplasia of vertebro-basilar system.

2009

We describe the case of a patient with atypical hemiplegic migraine and associated basilar symptoms, where a large patent foramen ovale (PFO) and hypoplasia of basilar artery were found. The longer period of 4-year remission of the headache attacks was coincident with the percutaneous PFO closure. When 5 years after, hemiplegic migraine attacks relapsed, with more relevant basilar symptoms, a mild re-opening of PFO was found. The atypical presentation of attacks with basilar symptoms and prolonged hemiplegia does not strictly fit the diagnostic criteria of ICHD-II.

AdultMalemedicine.medical_specialtyAuraMigraine with AuraClinical NeurologyForamen Ovale PatentHemiplegiaCase ReportNeurological disorderHemiplegic migraineRecurrencePFOmedicine.arteryBasilar arteryVertebrobasilar InsufficiencyMedicineHumansCardiac Surgical ProceduresBasilar type migrainebusiness.industryBasilar-Type MigraineAnticoagulantsBrainGeneral Medicinemedicine.diseaseMagnetic Resonance ImagingHypoplasiaMigraine with auraSurgeryAnesthesiology and Pain MedicineTreatment OutcomeVertebro-basilar system hypoplasiaMigraineBasilar ArteryPatent foramen ovalecardiovascular systemNeurology (clinical)sense organsmedicine.symptombusinessTomography X-Ray ComputedMagnetic Resonance AngiographyThe journal of headache and pain
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Screening for congenital renovascular hypoplasia and renal artery stenosis by acute converting enzyme inhibition.

1993

To evaluate the usefulness of the captopril test for identifying renal artery stenosis (RAS) and renovascular hypoplasia (RAH), we studied 48 hypertensive patients. In 20 hypertensives with screening procedures indicating renovascular disease and in 28 essential hypertensives (EH), the plasma renin activity (PRA) responses to an oral test dose of captopril (50 mg) were studied. A 60-min post-captopril PRA increase of 150% (or 400% if baseline PRA < or = 3 ng/ml/h) was considered as positive. Renal angiography was performed in all cases. Among the 20 renovascular hypertensive patients, RAH in 9 and RAS in 11 subjects were proved by angiography. The captopril test in all patients with RAH res…

AdultMalemedicine.medical_specialtyCaptoprilAdolescentUrologyAdministration OralAngiotensin-Converting Enzyme Inhibitorsurologic and male genital diseasesRenal artery stenosisKidneyRenal Artery ObstructionPlasma renin activityDiagnosis DifferentialRenin-Angiotensin SystemInternal medicinemedicine.arteryReninmedicineHumansRenal arteryScreening proceduresAgedKidneybusiness.industryKidney metabolismCaptoprilMiddle Agedmedicine.diseasefemale genital diseases and pregnancy complicationsHypoplasiaRadiographymedicine.anatomical_structureEndocrinologyHypertension RenovascularFemaleKidney Diseasesbusinesshormones hormone substitutes and hormone antagonistscirculatory and respiratory physiologymedicine.drugNephron
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Evaluation of esophagogastric junction relaxation by 4-second Integrated Relaxation Pressure in achalasia using High Resolution Manometry with water-…

2014

Background Relaxation of the esophagogastric junction (EGJ) is now evaluated calculating 4-second integrated relaxation pressure (4-s IRP) by high resolution manometry (HREPT). Solid-state catheters have been used to define abnormal values. Our aim was to evaluate 4-s IRP in esophageal achalasia using HREPT with perfused catheters. Methods From June 2009 to June 2013, 936 HREPT studies have been performed in our unit. Of these, 194 patients having treated achalasia were excluded. Control group was constituted by 695 patients without achalasia, and 47 patients with untreated achalasia constituted the study group. HREPT was performed with water-perfused catheters. To establish the cut-off val…

AdultMalemedicine.medical_specialtyCathetersAdolescentManometryPhysiologyMuscle RelaxationAchalasiaGastroenterologyYoung AdultReference ValuesInternal medicinePressuremedicineotorhinolaryngologic diseasesHumanssclerodermaEsophagogastric junctionHigh resolution manometryAgedAged 80 and overReceiver operating characteristicEndocrine and Autonomic Systemsbusiness.industryhigh resolution manometryGastroenterologyArea under the curveWaterMuscle SmoothMiddle Agedlower esophageal sphincter relaxationmedicine.diseaseEsophageal Achalasiaachalasiaesophageal manometryROC CurveArea Under Curveesophagogastric junction relaxationFemaleEsophagogastric JunctionNuclear medicinebusiness
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A functional study of the esophagus in patients with non-cardiac chest pain and dysphagia.

2015

Background/Aims: Nutcracker esophagus and non-specific motility disorders are the main causes of non-cardiac chest pain (NCCP), with gastroesophageal reflux in 60% of cases. Achalasia and diffuse esophageal spasm are the most frequent anomalies described in patients with dysphagia. The goal of this study was to evaluate the occurrence of esophageal body and lower esophageal sphincter motor abnormalities in patients with dysphagia, NCCP, or both. Materials and Methods: This study is a retrospective analysis of 716 patients with NCCP and/or dysphagia tested between January 1994 and December 2010. 1023 functional studies were performed, 707 of which were esophageal manometries, 225 esophageal …

AdultMalemedicine.medical_specialtyChest PainManometryAchalasiaChest painEsophaguGastroenterologyEsophageal Sphincter LowerEsophagusRetrospective StudieInternal medicineotorhinolaryngologic diseasesmedicineHumansIn patientEsophagusDeglutition DisorderNon-cardiac chest painAgedRetrospective StudiesSettore MED/12 - Gastroenterologiabusiness.industryMedicine (all)Esophageal dyskinesiaDysphagia; Esophageal dyskinesia; Gastroesophageal reflux; Non-cardiac chest pain; Adult; Aged; Chest Pain; Deglutition Disorders; Esophageal Achalasia; Esophageal Sphincter Lower; Esophageal Sphincter Upper; Esophagus; Female; Gastroesophageal Reflux; Humans; Hydrogen-Ion Concentration; Male; Manometry; Middle Aged; Retrospective Studies; Gastroenterology; Medicine (all)RefluxGastroenterologyNutcracker esophagusDysphagiaHydrogen-Ion ConcentrationMiddle Agedmedicine.diseaseEsophageal Sphincter UpperDysphagiaSurgeryEsophageal AchalasiaSettore MED/18 - Chirurgia Generalemedicine.anatomical_structureGastroesophageal RefluxEsophageal spasmFemalemedicine.symptombusinessDeglutition DisordersHumanThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
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Correction of Constricted Ear

1995

We present a case of moderate constricted ear corrected using a modified Tanzer's technique for the helical deformity and lengthening the lower third of the pinna with a cutaneous transposition flap from the retroauricular area. The operation begins with a rapid intraoperative expansion of the retroauricular skin. Then an incision is made on the posteromedial ear aspect and the ear is degloved using a subperichondral plane. The upper pole of the cartilage is expanded and rearranged by an anteriorly pedicled helical flap and a cartilaginous graft is taken from the constricted part of the concha. The lower third of the pinna is lengthened by a cutaneous transposition flap from the retroauricu…

AdultMalemedicine.medical_specialtyConstricted earSurgical FlapsmedicineDeformityHumansLocal anesthesiaEar ExternalSurgery PlasticSurgical Flapsbiologybusiness.industryCartilagePinnaAnatomybiology.organism_classificationmedicine.diseaseHypoplasiaSurgeryPlastic surgerymedicine.anatomical_structureSurgeryEar Cartilagemedicine.symptombusinessAnnals of Plastic Surgery
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Single versus double femtosecond laser pass for incomplete laser in situ keratomileusis flap in contralateral eyes: Visual and optical outcomes

2011

Purpose To evaluate visual acuity, refractive outcomes, and anterior corneal higher-order aberrations (HOAs) after myopic laser in situ keratomileusis (LASIK) with uneventful single femtosecond laser pass versus double pass performed for intraoperative suction loss. Setting Private refractive surgery center, Valencia, Spain. Design Cohort study. Methods After the LASIK flap was created with a single pass of an Intralase femtosecond laser in 1 eye and a double pass in the fellow eye, the ablation was performed with a Visx S2 laser. At 12 months, the refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, and anterior corneal HOAs were measured with 4.0 mm and 6.0 mm pup…

AdultMalemedicine.medical_specialtyCorneal Wavefront AberrationVisual acuitygenetic structuresCorneal Stromamedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityKeratomileusisRefraction OcularSurgical Flapslaw.inventionCohort StudiesYoung AdultlawRefractive surgeryOphthalmologyMyopiamedicineHumansDioptreRetrospective Studiesbusiness.industryLASIKMiddle AgedLaserAblationeye diseasesSensory SystemsSurgeryOphthalmologyTreatment OutcomeFemtosecondFemaleLasers ExcimerSurgerysense organsmedicine.symptombusinessJournal of Cataract and Refractive Surgery
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Clinical characteristics and determinants of the phenotype in TMEM43 arrhythmogenic right ventricular cardiomyopathy type 5.

2020

Arrhythmogenic right ventricular cardiomyopathy type V (ARVC-5) is the most aggressive heterozygous form of ARVC. It is predominantly caused by a fully penetrant mutation (p.S358L) in the nondesmosomal gene TMEM43-endemic to Newfoundland, Canada. To date, all familial cases reported worldwide share a common ancestral haplotype. It is unknown whether the p.S358L mutation by itself causes ARVC-5 or whether the disease is influenced by genetic or environmental factors. The purpose of this study was to examine the phenotype, clinical course, and the impact of exercise on patients with p.S358L ARVC-5 without the Newfoundland genetic background. We studied 62 affected individuals and 73 noncarrie…

AdultMalemedicine.medical_specialtyDNA Mutational AnalysisMutation MissenseDisease030204 cardiovascular system & hematologyVentricular Function LeftRight ventricular cardiomyopathySudden cardiac deathElectrocardiography03 medical and health sciences0302 clinical medicinePhysiology (medical)Internal medicinemedicineGeneticsHumans030212 general & internal medicineExerciseArrhythmogenic Right Ventricular DysplasiaEjection fractionTMEM43business.industryIncidence (epidemiology)HaplotypeMembrane ProteinsStroke VolumeDNAmedicine.diseasePhenotypePedigree3. Good healthPhenotypeMutation (genetic algorithm)CardiologyFemaleCardiology and Cardiovascular MedicinebusinessArrhythmogenic right ventricular cardiomyopathyArrhythmia
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Circadian gastric acidity in Helicobacter pylori positive ulcer patients with and without gastric metaplasia in the duodenum.

1996

BACKGROUND: The presence of gastric metaplasia allows helicobacter pylori to colonise the duodenum and this condition is thought to be acquired as a response to acid hypersecretion. This functional disorder, however, is present only in a subgroup of duodenal ulcer patients and, in addition, surface gastric metaplasia has been frequently found in the proximal duodenum of normal subjects and patients with non-ulcer dyspepsia, who cannot be certainly considered as acid hypersecretors. AIMS: To clarify the role of acid in inducing gastric type epithelium in the duodenum. This study aimed at assessing whether the pattern of circadian gastric acidity differs between H pylori positive duodenal ulc…

AdultMalemedicine.medical_specialtyDuodenumSpirillaceaeGastroenterologyEpitheliumHelicobacter InfectionsGastric AcidInternal medicineMetaplasiaBiopsymedicineHumansAntrumMonitoring PhysiologicAnalysis of VarianceMetaplasiabiologymedicine.diagnostic_testHelicobacter pyloribusiness.industrydigestive oral and skin physiologyStomachGastroenterologyHistologyHelicobacter pyloriHydrogen-Ion ConcentrationMiddle Agedbiology.organism_classificationdigestive system diseasesCircadian Rhythmmedicine.anatomical_structureGastric MucosaDuodenal UlcerDuodenumFemaleGastritismedicine.symptombusinessResearch Article
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Comparison of methylene blue-directed biopsies and four-quadrant biopsies in the detection of high-grade intraepithelial neoplasia and early cancer i…

2006

Background. Barrett’s oesophagus embodies the risk of malignant transformation. High-grade intraepithelial neoplasia and early cancer in Barrett’s oesophagus are often discrete or macroscopically occult lesions and show a patchy distribution and therefore, directed biopsies in combination with four-quadrant random biopsies are the gold standard for surveillance. Aims. The aim of this prospective study was to compare methylene blue staining and random biopsies in patients with early Barrett’s neoplasia. Patients and methods. Eighty-six patients (mean age 65 ± 8 years) with histologically proven but macroscopically in evident high-grade intraepithelial neoplasia (n = 17) or early cancer in Ba…

AdultMalemedicine.medical_specialtyEsophageal NeoplasmsBiopsyGastroenterologyStainChromoendoscopyBarrett Esophaguschemistry.chemical_compoundInternal medicinemedicineHumansProspective StudiesProspective cohort studyAgedAged 80 and overIntraepithelial neoplasiaHepatologymedicine.diagnostic_testbusiness.industryGastroenterologyMiddle AgedStainingEndoscopyMethylene BluechemistryHigh Grade Intraepithelial NeoplasiaFemalebusinessCarcinoma in SituMethylene blueDigestive and Liver Disease
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Survival study of leukoplakia malignant transformation in a region of northern Spain

2017

Background Oral leukoplakia is the most common potentially malignant disorder (PMD) of the oral cavity. The objectives of this study are to determine the clinicopathologic features in a group of patients with oral leukoplakia of Northern Spain (Galicia), determining the factors associated to clinical risk and analyzing the malignant transformation of these patients. Material and Methods We included 85 patients. We recorded sex and age, habits like alcohol and tobacco, size, clinical appearance, site, number of lesions, and presence or absence of dysplasia. We assess the association between risk factors and transformation and developed a logistic regression analysis. Finally we used the Kapl…

AdultMalemedicine.medical_specialtyGastroenterologyMalignant transformationYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineOral and maxillofacial pathologyCarcinomaHumansMedicineRisk factorGeneral DentistrySurvival rateSurvival analysisAgedLeukoplakiaAged 80 and overOral Medicine and Pathologybusiness.industryResearch030206 dentistryMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseSurvival Ratestomatognathic diseasesCell Transformation NeoplasticOtorhinolaryngologySpainDysplasia030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASFemaleSurgeryLeukoplakia OralbusinessMedicina Oral Patología Oral y Cirugia Bucal
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