Search results for "lcsh:M"
showing 10 items of 4818 documents
Surface Characteristics of Machined Polystyrene with 3D Printed Thermoplastic Tool
2020
An effort is made in this work to appraise the surface characteristics of machined expandable polystyrene (EPS) with a novel 3D printed thermoplastic acrylonitrile-butadiene-styrene (ABS) tool. Linear grooves on EPS were made on a vertical milling machine that was modified to conduct experiments in the laboratory. The tests were designed as per the Taguchi L9 based factorial design of experimentation while varying process parameters such as depth of cut, spindle speed, and feed rate. The machining responses dimensional accuracy and surface roughness of the machined grooves were studied. Furthermore, the surface topography of the machined specimens was considered to investigate the mechanism…
Experimental Research on the Cutting of Metal Materials by Electrical Discharge Machining with Contact Breaking with Metal Band as Transfer Object
2020
The scientific paper presents practical research carried out by a mixed team of Romanian researchers from universities and the business environment. The research consists in applying the process of cutting metallic materials through electrical discharge machining with contact breaking using a metal band as a transfer object. The research was implemented with the help of a specially designed installation in the laboratory and subsequently all the necessary steps were taken to obtain the patent for it. Various metallic materials were cut using this process, but first of all, high alloy steels. In the global research conducted by the authors, active experimental programs and classic experiment…
Using Inverse Reinforcement Learning with Real Trajectories to Get More Trustworthy Pedestrian Simulations
2020
Reinforcement learning is one of the most promising machine learning techniques to get intelligent behaviors for embodied agents in simulations. The output of the classic Temporal Difference family of Reinforcement Learning algorithms adopts the form of a value function expressed as a numeric table or a function approximator. The learned behavior is then derived using a greedy policy with respect to this value function. Nevertheless, sometimes the learned policy does not meet expectations, and the task of authoring is difficult and unsafe because the modification of one value or parameter in the learned value function has unpredictable consequences in the space of the policies it represents…
Me, My Bot and His Other (Robot) Woman? Keeping Your Robot Satisfied in the Age of Artificial Emotion
2018
With a backdrop of action and science fiction movie horrors of the dystopian relationship between humans and robots, surprisingly to date-with the exception of ethical discussions-the relationship aspect of humans and sex robots has seemed relatively unproblematic. The attraction to sex robots perhaps is the promise of unproblematic affectionate and sexual interactions, without the need to consider the other&rsquo
Grading investment diversification options in presence of non-historical financial information
2021
Modern portfolio theory deals with the problem of selecting a portfolio of financial assets such that the expected return is maximized for a given level of risk. The forecast of the expected individual assets’ returns and risk is usually based on their historical returns. In this work, we consider a situation in which the investor has non-historical additional information that is used for the forecast of the expected returns. This implies that there is no obvious statistical risk measure any more, and it poses the problem of selecting an adequate set of diversification constraints to mitigate the risk of the selected portfolio without losing the value of the non-statistical information owne…
PSYCHOLOGICZNE I PRAWNE ASPEKTY MOBBINGU W MIEJSCU PRACY
2018
Przemoc w miejscu pracy pojawia się z coraz większą a zarazem niepokojącą częstotliwością. Mobbing traktowany jest jako przykład patologii obserwowanej w organizacji. Stąd konieczność spojrzenia na mobbing w sposób wieloaspektowy. Celem artykułu jest przybliżenie psychologicznej natury zjawiska mobbingu, a także wskazanie na mobbing w kontekście polskiego prawa pracy. W artykule zwrócono uwagę na dwie przestrzenie, w jakich należy przyjrzeć się przemocy w organizacji. Pierwsza część artykułu poświęcona jest aspektom związanym z psychologią zdrowia i psychologią organizacji. Druga część artykułu poświęcona jest przestrzeni prawa pracy. W pierwszej części artykułu skupiono się na psychologicz…
Estudio descriptivo y comparativo de factores de riesgo cardiovascular y actividad física en pacientes con síndrome coronario agudo
2018
Resumen: Objetivo: Analizar diversos factores de riesgo cardiovascular en función de la actividad física realizada en pacientes con síndrome coronario agudo (SCA). Diseño: Estudio observacional transversal. Emplazamiento: Servicio de prevención cardiovascular hospitalario (Departamento Salud, Valencia, España). Participantes: Un total de 401 sujetos con SCA y alta hospitalaria entre 2 y 3 meses previos a la medición, entre 30 y 80 años; ausencia de contraindicación para realizar actividad física; sin participación previa en programas de rehabilitación cardiaca. Mediciones principales: Se estimó el equivalente metabólico MET (kcal/kg) según el tipo de actividad, frecuencia, duración e intens…
Pediatric Psychology
2021
The attention and the intervention of psychology in the field of pediatrics, especially regarding mothers and childcare, whether in a hospital or not, is extremely longstanding [...]
Next‐Generation Sequencing‐Based RiboMethSeq Protocol for Analysis of tRNA 2′‐O‐Methylation
2017
Analysis of RNA modifications by traditional physico‐chemical approaches is labor intensive, requires substantial amounts of input material and only allows site‐by‐site measurements. The recent development of qualitative and quantitative approaches based on next‐generation sequencing (NGS) opens new perspectives for the analysis of various cellular RNA species. The Illumina sequencing‐based RiboMethSeq protocol was initially developed and successfully applied for mapping of ribosomal RNA (rRNA) 2′‐O‐methylations. This method also gives excellent results in the quantitative analysis of rRNA modifications in different species and under varying growth condi…
Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer
2020
Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies. Sorafenib is the first line molecular targeted therapy for patients in advanced stage of HCC. The present study shows that Sorafenib exerts free radical scavenging properties associated with the downregulation of nuclear factor E2-related factor 2 (Nrf2)-regulated thioredoxin 1 (Trx1) expression in liver cancer cells. The experimental downregulation and/or overexpression strategies showed that Trx1 induced activation of nitric oxide synthase (NOS) type 3 (NOS3) and S-nitrosation (SNO) of CD95 rece…