Search results for "lesion"

showing 10 items of 1094 documents

Preliminary experience with the application of Gadolinium-DTPA before MR imaging-guided laser-induced interstitial thermotherapy of brain tumors

1997

The purpose of this study was to investigate the potential value of i.v. gadolinium-diethylenetriamine penta-acetic acid (Gd-DTPA) applied before MRI-guided laser-induced interstitial thermotherapy (LITT) of brain tumors without original enhancement, especially in defining total lesion size during therapy. MRI-guided LITT was performed on two patients with astrocytoma WHO II. For both patients, Gd-DTPA was administered intravenously after a first irradiation period and LITT was continued after pulling back the light guide to coagulate the upper parts of the tumor. In both patients, the whole irreversible damaged zone of the second irradiation period after Gd-DTPA showed an intense increase …

AdultGadolinium DTPAMalePathologymedicine.medical_specialtySpatial expansionGadoliniumchemistry.chemical_elementAstrocytomaDrug Administration ScheduleLesionGadolinium DTPAOrganometallic CompoundsmedicineHumansRadiology Nuclear Medicine and imagingBrain Neoplasmsbusiness.industryAstrocytomaLight guideHyperthermia InducedPentetic AcidImage Enhancementmedicine.diseaseMagnetic Resonance ImagingMr imagingchemistryFemaleLaser TherapySignal intensitymedicine.symptomNuclear medicinebusinessFollow-Up StudiesJournal of Magnetic Resonance Imaging
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Multiple renal aspergillus abscesses in an AIDS patient: contrast-enhanced helical CT and MRI findings.

1999

Renal insufficiency or allergic reactions for X-ray contrast agents are frequent limitations in immunocompromised hosts such as neutropenic or AIDS patients. Due to a better tolerance of contrast agents in MRI, this technique is well suited for investigation of parenchymal organs. We demonstrate an allergic AIDS patient who presented with fever and flank pain. At sonography, anechoic renal lesions were supposed to be non-complicated cysts; however, on T2-weighted MRI, the center was of high signal. Dynamic contrast-enhanced MRI of the kidneys demonstrated an enhancing rim with ill-defined margins. The lesions were supposed to be multiple bilateral abscesses. Due to the multiple dynamic cont…

AdultGadolinium DTPAmedicine.medical_specialtyPathologyBiopsyIohexolContrast MediaAspergillosisAspergillus fumigatusLesionDiagnosis DifferentialFatal OutcomeParenchymaBiopsymedicineAspergillosisHumansRadiology Nuclear Medicine and imagingNeuroradiologyKidneybiologymedicine.diagnostic_testAIDS-Related Opportunistic InfectionsPyelonephritisbusiness.industryAspergillus fumigatusInterventional radiologyGeneral Medicinebiology.organism_classificationmedicine.diseaseMagnetic Resonance ImagingAbscessmedicine.anatomical_structureFemaleRadiologymedicine.symptombusinessTomography X-Ray ComputedFollow-Up StudiesEuropean radiology
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The phenotype of gastric mucosa coexisting with Barrett's oesophagus.

2001

Barrett's oesophagus complicates the gastro-oesophageal acid reflux. Helicobacter pylori infection, particularly with cagA positive strains, induces inflammatory/atrophic lesions of the gastric mucosa, which may impair acid output. No systematic study has investigated the phenotype of the gastric mucosa coexisting with Barrett's oesophagus. This study was designed to identify the phenotype of gastric mucosa associated with Barrett's oesophagus.In this retrospective case control study, the phenotype of the gastric mucosa was histologically characterised in 53 consecutive patients with Barrett's oesophagus and in 53 (sex and age matched) non-ulcer dyspeptic controls. Both patients and control…

AdultGastritis AtrophicMalemedicine.medical_specialtyPathologyAtrophic gastritisBiopsySpirillaceaeBarrett's oesophagus gastritis in Barrett's oesophagus Barrett's oesophagus and gastric precancerous lesionsdigestive systemGastroenterologyHelicobacter InfectionsPathology and Forensic MedicineBarrett's oesophagus and gastric precancerous lesionsBarrett EsophagusInternal medicineotorhinolaryngologic diseasesGastric mucosamedicineHumansCagAAgedRetrospective StudiesAged 80 and overHelicobacter pyloribiologybusiness.industrygastritis in Barrett's oesophagusStomachdigestive oral and skin physiologyIntestinal metaplasiaGeneral MedicineMiddle AgedHelicobacter pyloribiology.organism_classificationmedicine.diseasedigestive system diseasesBarrett's oesophagussurgical procedures operativePhenotypemedicine.anatomical_structureGastric MucosaCase-Control StudiesPapersFemaleGastritismedicine.symptombusiness
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Multifocal choroiditis: Indocyanine green angiographic features

2001

The aim of this study is to retrospectively evaluate the indocyanine green (ICG) angiographic features in 13 patients affected by multifocal choroiditis. We identified two clinical and angiographic patterns. The ‘active’ pattern showed hypofluorescence up to the late phases and more extensive choroidal involvement than presumed by ophthalmoscopy and fluorescein angiography. In the ‘inactive’ pattern, ICG angiography showed hypofluorescence during all the phases: no increase in lesion number was observed between early and late phases. Choroidal neovascularization was present in 10 patients, and it was bilateral in 2 of these: it occurred only in the inactive stage. The appearance of choroida…

AdultIndocyanine Greenmedicine.medical_specialtyPathologyChoroiditisFundus OculiEye diseaseOcular inflammationLesion NumberOphthalmoscopychemistry.chemical_compoundOphthalmologymedicineHumansFluorescein AngiographyIndocyanine green angiographyRetrospective Studiesmedicine.diagnostic_testbusiness.industrySettore MED/30 - Malattie Apparato VisivoGeneral MedicineMiddle Agedmedicine.diseaseFluorescein angiographyMultifocal choroiditisChoroidal Neovascularizationeye diseasesSensory SystemsOphthalmoscopyOphthalmologyChoroidal neovascularizationchemistryAngiographyFemalesense organsmedicine.symptombusinessIndocyanine greenRetinopathy
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MAGIC-5: an Italian mammographic database of digitised images for research

2008

The implementation of a database of digitised mammograms is discussed. The digitised images were collected beginning in 1999 by a community of physicists in collaboration with radiologists in several Italian hospitals as a first step in developing and implementing a computer-aided detection (CAD) system. All 3,369 mammograms were collected from 967 patients and classified according to lesion type and morphology, breast tissue and pathology type. A dedicated graphical user interface was developed to visualise and process mammograms to support the medical diagnosis directly on a high-resolution screen. The database has been the starting point for developing other medical imaging applications,…

AdultLesion typeDatabases Factualmammographic databaseBreast NeoplasmsCADcomputer.software_genreSensitivity and SpecificityDatabaseMedical imagingHumansMedicineMammographyRadiology Nuclear Medicine and imagingGridMedical image processingMedical diagnosisAgedRetrospective StudiesGraphical user interfacecomputer assisted detectionDatabasePoint (typography)medicine.diagnostic_testbusiness.industryMagic (programming)General MedicineMiddle Agedimage processingRadiographic Image EnhancementItalyRadiographic Image Interpretation Computer-AssistedFemaleTomography X-Ray Computedbusinessdatabase; mammography; medical image processing; gridcomputerMammographyLa radiologia medica
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Focal lesions in cirrhotic liver: what else beyond hepatocellular carcinoma?

2014

Detection and characterization of focal lesions in the cirrhotic liver may pose a diagnostic dilemma. Several benign and malignant lesions may be found in a cirrhotic liver along with hepatocellular carcinoma (HCC), and may exhibit typical or atypical imaging features. In this pictorial essay, we illustrate computed tomography and magnetic resonance imaging findings of lesions such as simple bile duct cysts, hemangioma, focal nodular hyperplasia-like nodules, peribiliary cysts, intrahepatic cholangiocarcinoma, lymphoma, and metastases, all of which occur in cirrhotic livers with varying prevalences. Pseudolesions, such as perfusion anomalies, focal confluent fibrosis, and segmental hyperpla…

AdultLiver CirrhosisMalePathologymedicine.medical_specialtyCirrhosisCarcinoma HepatocellularLymphomaBile Duct DiseasesHemangiomaCholangiocarcinomaFibrosismedicineCarcinomaPrevalenceHumansRadiology Nuclear Medicine and imagingAbdominal ImagingNeoplasm MetastasisIntrahepatic CholangiocarcinomaAgedFocal liver lesions CT MRImedicine.diagnostic_testbusiness.industryCystsLiver DiseasesLiver NeoplasmsMagnetic resonance imagingHyperplasiaMiddle Agedmedicine.diseaseMagnetic Resonance ImagingBile Ducts IntrahepaticBile Duct NeoplasmsLiverFocal Nodular HyperplasiaHepatocellular carcinomaFemaleRadiologyCardiology and Cardiovascular MedicinebusinessHemangiomaTomography X-Ray Computed
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Hepatocellular carcinoma in cirrhotic patients at multidetector CT: hepatic venous phase versus delayed phase for the detection of tumour washout.

2011

OBJECTIVES: Our aim was to compare retrospectively hepatic venous and delayed phase images for the detection of tumour washout during multiphasic multidetector row CT (MDCT) of the liver in patients with hepatocellular carcinoma (HCC). METHODS: 30 cirrhotic patients underwent multiphasic MDCT in the 90 days before liver transplantation. MDCT was performed before contrast medium administration and during hepatic arterial hepatic venous and delayed phases, images were obtained at 12, 55 and 120 s after trigger threshold. Two radiologists qualitatively evaluated images for lesion attenuation. Tumour washout was evaluated subjectively and objectively. Tumour-to-liver contrast (TLC) was measured…

AdultLiver CirrhosisMalemedicine.medical_specialtyCarcinoma Hepatocellularmedicine.medical_treatmentLiver transplantationLesionmedicineHumansRadiology Nuclear Medicine and imagingAgedRetrospective StudiesFull Paperbusiness.industryLiver NeoplasmsLiver CT HCCWashoutVenous phaseGeneral MedicineDelayed phaseMiddle AgedHCCSmedicine.diseasedigestive system diseasesLiver TransplantationContrast mediumHepatocellular carcinomaFemaleRadiologymedicine.symptomSettore MED/36 - Diagnostica Per Immagini E RadioterapiaTomography X-Ray Computedbusiness
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Analysis of different contrast enhancement patterns after microbubble-based contrast agent injection in liver hemangiomas with atypical appearance on…

2006

BACKGROUND: We describe different possible enhancement patterns in liver hemangiomas with atypical appearance on baseline ultrasound after microbubble-based contrast agent injection. METHODS: From a series of 253 consecutive lesions that were indeterminate on baseline ultrasound and then scanned after injection of air-filled microbubble contrast agent, 65 focal liver lesions were retrospectively selected on the basis of a diagnosis of liver hemangioma on multiphase contrast-enhanced computed tomography (n = 23), magnetic resonance imaging (n = 27), or histology (n = 15). Each lesion was scanned during arterial phase (30 s after microbubble injection) and late phase (5 min after injection). …

AdultLiver CirrhosisMalemedicine.medical_specialtyUrologyLiver CirrhosiContrast MediaLesionAngiomaPolysaccharidesInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingAgedUltrasonographyMicrobubblesRadiological and Ultrasound Technologymedicine.diagnostic_testbusiness.industryLiver NeoplasmsUltrasoundGastroenterologyMagnetic resonance imagingHistologyGeneral MedicineultrasonographyMiddle AgedHepatologymedicine.diseaseImage EnhancementHemangioma; ultrasonography; Image Enhancement; Liver Cirrhosis; Liver Neoplasms; MicrobubblesLiver NeoplasmLiver HemangiomaMicrobubblesFemaleRadiologymedicine.symptombusinessNuclear medicineHemangioma
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HRCT and scleroderma: semiquantitative evaluation of lung damage and functional abnormalities.

2007

This study sought to validate the Warrick score in the assessment of lung involvement in systemic sclerosis (SSc) and correlate the results with functional abnormalities. In addition, we propose the use of high resolution computed tomography (HRCT) indices of alveolitis and fibrosis to discriminate between different stages of the disease.Thirty-one patients with SSc (16 with the diffuse form and 15 with the limited form) underwent functional and HRCT evaluations of the lung. The semiquantitative evaluation of radiological involvement, as proposed by Warrick, provides a score for each lesion based on the severity and the extent of the pulmonary damage. In addition to the total score, indices…

AdultLung DiseasesMalemedicine.medical_specialtyHigh-resolution computed tomographyGastroenterologySensitivity and SpecificitySeverity of Illness IndexLesionFibrosisDLCOScleroderma LimitedInternal medicineForced Expiratory VolumePulmonary fibrosisSeverity of illnessmedicineHumansRadiology Nuclear Medicine and imagingLung volumesAgedLungScleroderma Systemicmedicine.diagnostic_testbusiness.industryTotal Lung CapacityGeneral Medicinerespiratory systemMiddle Agedmedicine.diseaseFibrosisrespiratory tract diseasesRespiratory Function TestsPulmonary Alveolimedicine.anatomical_structureScleroderma DiffuseFemalemedicine.symptomlung scleroderma HRCTNuclear medicinebusinessTomography X-Ray ComputedLa Radiologia medica
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Metastatic Anterior Chamber Non-Hodgkin Lymphoma in a Patient With Acquired Immunodeficiency Syndrome

1997

Purpose To alert ophthalmologists to the possibility of metastatic anterior chamber intraocular non-Hodgkin lymphoma in patients with acquired immunodeficiency syndrome (AIDS). Methods We examined a 19-year-old man with AIDS who had an anterior uveitis with pseudohypopyon and a history of 2 months of malaise. A specimen of the lesion was obtained with a 25-gauge needle for pathologic examination. RESULTS: Systemic exploration showed hepatomegaly. Abdominal computed tomography showed multiple lesions in the liver and spleen. Fine-needle aspiration disclosed a high-grade non-Hodgkin lymphoma. The result of a fine-needle aspiration obtained from a lesion in the anterior chamber was consistent …

AdultMaleAcquired Immunodeficiency SyndromePathologymedicine.medical_specialtyAnterior Chamberbusiness.industryEye NeoplasmsLymphoma Non-HodgkinEye diseaseBiopsy Needlemedicine.diseaseLymphomaMetastasisMalaiseLesionOphthalmologyImmunopathologymedicineHumansmedicine.symptombusinessComplicationUveitisAmerican Journal of Ophthalmology
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