Search results for "liikakasvu"
showing 3 items of 3 documents
Myostatin and related proteins on the control of skeletal muscle mass and capillary density
2013
Skeletal muscle wasting is a feature of many pathological conditions such as muscular dystrophies, cancer and diabetes. Human ageing also results in the progressive loss of muscle mass and strength, a condition known as sarcopenia (or myopenia). Therefore, interventions that can reverse or slow down muscle loss are highly desirable. The TGF-β member myostatin is a well-known inhibitor of skeletal muscle growth, but it may also, if deleted, decrease muscle oxidative capacity. We have used the activin receptor 2B (ActR2B) fused to the Fc region of immunoglobulin G (ActR2B-Fc) as a trap to sequester myostatin and inhibit its activity. We sought to evaluate possible differences between doses an…
Effects of post-workout supplements and resistance training on serum metabolome, muscle strength and muscle hypertrophy
2017
Human metabolism is a complex mixture of different metabolites and metabolic pathways that are interrelated. Compared to standard biomarker assessments, metabolomics gives a broader perspective of the whole ensemble thus deepening the understanding of human physiology and pathophysiology. The aim of this study was to provide a comprehensive overview of the effects of different post-exercise supplementation regimens and different resistance training programs on serum metabolome and resistance training adaptations. 60 healthy men volunteers (mean ± SD: age 32.6±6.7 y; height 1.80±0.1 m; weight 82.8±10.4 kg and BMI 25.5±3.0 kg/m2) were included in the study. All the participants went through a…
Effects of resistance training frequency on muscle strength, activity and mass during a 24-week intervention in the elderly
2016
Elderly populations are increasingly affected by sarcopenia, dynapenia and osteoporosis. They all increase frailty and decrease quality of life and life-expectancy. Resistance training (RT) has been reported extensively as a tool that can prevent, counter and in some cases reverse the course of the abovementioned diseases. Several studies covering RT adaptations in elderly populations have investigated periods between 6 up to 88 weeks with different frequencies, from 1 to 3 trainings / week and a wide range of intensities (30-85% or one repetition maximum) and different volumes. The aim of this study was to investigate the effect of different training frequencies (one, two or three times / …