Search results for "limoni"

showing 10 items of 36 documents

Nimbolide inhibits 2D and 3D prostate cancer cells migration, affects microtubules and angiogenesis and suppresses B-RAF/p.ERK-mediated in vivo tumor…

2021

Abstract Background Prostate cancer (PCa) is the most prominent malignancy among men worldwide. PCa cells have a high tendency to metastasize to various distant organs, and this activity is the main cause of PCa mortality. Nimbolide is a promising phytochemical constituent of neem Azadirachta indica (Meliaceae). Previous studies showed that nimbolide exhibited potent anticancer activity however, its role against PCa tumorigenesis has not been fully elucidated. Purpose Our work aims to explore the role of nimbolide in regulating the essential tumor-associated processes involved in the metastatic cascade in PCa cells. Study design Cytotoxicity assay, wound healing and spheroid invasion assays…

LimoninsMaleAngiogenesisPharmaceutical Sciencemedicine.disease_causeMicrotubulesMiceDU145In vivoCell Line TumorDrug DiscoverymedicineAnimalsHumansCytotoxicityCell ProliferationPharmacologyTube formationChemistryProstatic NeoplasmsBlotComplementary and alternative medicineCell cultureCancer researchMolecular MedicineCarcinogenesisPhytomedicine
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Cytotoxicity of botanicals and isolated phytochemicals from Araliopsis soyauxii Engl. (Rutaceae) towards a panel of human cancer cells.

2020

Abstract Ethnopharmacological relevance Araliopsis soyauxii Engl. (Rutaceae) is a Cameroonian medicinal plant traditionally used to treat lung diseases, malaria, and gonorrhea. It has been demonstrated that infectious disease contribute to about 20% of all human tumours. Aims of the study (1) To perform a phytochemical investigation of the dichloromethane-methanol 1:1 extracts of the bark (ASB), roots (ASR), and leaves (ASL) from Araliopsis soyauxii; (2) to evaluate the cytotoxicity of extracts and isolated compounds; (3) to determine the mode of induction of apoptosis of ASB and kihadanin B (12). Materials and methods Fourteen constituents of the crude extracts were isolated by column chro…

LimoninsPhytochemicalsApoptosisFlow cytometry03 medical and health sciencesInhibitory Concentration 500302 clinical medicineAnnexinNeoplasmsDrug DiscoverymedicineCytotoxic T cellBenzoxepinsHumansCytotoxicityRutaceae030304 developmental biologyPharmacologychemistry.chemical_classificationMembrane Potential Mitochondrial0303 health sciencesReactive oxygen speciesmedicine.diagnostic_testDose-Response Relationship DrugChemistryPlant ExtractsCell Cycle CheckpointsHep G2 CellsCell cycleHCT116 CellsMolecular biologyAntineoplastic Agents PhytogenicMitochondriaOxidative StressPhytochemicalApoptosis030220 oncology & carcinogenesisApoptosis Regulatory ProteinsReactive Oxygen SpeciesSignal TransductionJournal of ethnopharmacology
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Taxonomic complexity in the halophyte Limonium vulgare and related taxa (Plumbaginaceae): insights from analysis of morphological, reproductive and k…

2014

Part of a special issue on halophytes and saline adaptations Background and Aims Limonium is awell-known example of a group of plants that is taxonomically complex due to certain biological characteristics that hamper species’ delineation. The closely related polyploid species Limonium vulgare Mill., L. humile Mill. and L. narbonense Mill. are defined species and can be used for studying patterns of morphological and reproductive variation. The first two taxa are usually found in Atlantic Europe and the third in the Mediterranean region, but a numberof intermediate morphological formsmay be present alongside typical examples of these species. This study attempts to elucidate morphological, …

LimoniumBiodiversityPlant ScienceLimonium humileLimonium humileLimonium vulgaretaxonomyPlumbaginaceaePolyploidpollen-stigma dimorphismHeterostylyPhylogenypolyploidyPortugalbiologyEcologyReproductionLimonium narbonenseGenetic VariationSpecies diversitySalt-Tolerant PlantsArticlesBiodiversitybiology.organism_classificationBiological Evolutionkaryological polymorphismsTaxonSpainEvolutionary biologyhalophyteTaxonomy (biology)Limonium maritimumheterostylymorphometryAnnals of Botany
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A new polyploid species of Limonium (Plumbaginaceae) from the Western Mediterranean basin

2015

A new species of Plumbaginaceae, Limonium irtaensis, is described and illustrated from the Western Mediterranean basin (Iberian Peninsula). The new species is triploid (2n = 26) and shows a papillate stigma and pollen with a fine reticulate exine (B type). A detailed morphological description is given, and its main diagnostic characters are compared with the related species. Conservation status has been assessed according to the IUCN protocol.

LimoniumPlant ScienceBiologymedicine.disease_causebiology.organism_classificationMediterranean BasinPlumbaginaceaeReticulatePollenBotanymedicineIUCN Red ListConservation statusEudicotsEcology Evolution Behavior and SystematicsPhytotaxa
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Assessing Effects of Temperature Change on Four Limonium Species from Threatened Mediterranean Salt-Affected Habitats

2018

[EN] Evaluation of tolerance to temperatures in the germination stage is an important tool to foresee the possible effect of global warming. Moreover, establishing germination protocols for endemic and threatened species is most interesting for restoration and management plans that focus on habitat conservation. Seed germination was analysed in four species of the genus Limonium (L. virgatum, L. narbonense, L. girardianum and L. santapolense) growing in two saline habitats on the eastern coast of the Iberian Peninsula. The study aim was to compare responses of seed germination to different temperature regimes. Seeds were collected in two protected areas, `L¿Albufera de Valencia¿ (province o…

Salt marshes0106 biological sciencesMediterranean climateLimoniumRange (biology)BOTANICASoil characteristicsPlant ScienceHorticulture01 natural sciencesHalophytesHalophyteBotanyEndemismbiologyEndemicsEDAFOLOGIA Y QUIMICA AGRICOLA04 agricultural and veterinary sciencesSeed germinationbiology.organism_classificationHorticultureHabitatGerminationThreatened species040103 agronomy & agriculture0401 agriculture forestry and fisheriesAgronomy and Crop Science010606 plant biology & botanyNotulae Botanicae Horti Agrobotanici Cluj-Napoca
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Osservazioni sulle strategie riproduttive dei taxa appartenenti al gruppo di Limonium articulatum (Plumbaginaceae)

2014

Limonium articulatum (Plumbaginaceae) e le specie affini costituiscono un gruppo tassonomico riconosciuto da diversi autori che si rinviene lungo le coste della Corsica, Sardegna e dell’Arcipelago Toscano. In concomitanza con indagini morfometriche, sono state condotte osservazioni sulla biologia riproduttiva di queste specie su materiale d’erbario. Nelle specie a più ampia distribuzione, L. articulatum e L. contortirameum, si sono osservate solo combinazioni autoincompatibili. Lo stesso in L. caprarie, L. corsicum, L. strictissimum e L. tarcoense. In L. coralliforme, L. dolcheri, L. florentinum, L. tibulatium e L. ursanum sono state osservate combinazioni autofertili. Non si sono verificat…

Settore BIO/02 - Botanica SistematicaSettore BIO/03 - Botanica Ambientale E ApplicataLimonium Sistematica Impollinazione
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Typification of <em>Statice dichotoma</em> Cav. (Plumbaginaceae)

2013

A lectotype and an epitype are here designated for Statice dichotoma Cav. (Plumbaginaceae), an endemic taxon from the central part of the Iberian Peninsula, which is currently named Limonium dichotomum (Cav.) Kuntze

TaxonbiologyTypificationZoologyLimonium dichotomumPlant Sciencebiology.organism_classificationEcology Evolution Behavior and SystematicsPlumbaginaceaeAnales del Jardín Botánico de Madrid
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Plumbaginaceae – P. 131 in: GREUTER W., RAAB-STRAUBE VON E. (EDS.), Euro+Med Notulae, 5.

2011

6 new combiantions in Limonium are here proposed. A name is lectotypified.

Taxonomy Nomenclature Limonium Statice
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1240 Scogliere con vegetazione delle coste mediterranee con Limonium spp. endemici

2016

VegetazioneLimoniumDirettiva HabitatHabitat Natura 2000 Monitoring ItalySettore BIO/03 - Botanica Ambientale E Applicata
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Anticancer effect of citrus limonoids: review of the available evidence.

2012

antioxidant compuonds limonin anticancerSettore AGR/15 - Scienze E Tecnologie Alimentari
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