Search results for "link"

showing 10 items of 1973 documents

An Updated Review on the Synthesis and Antibacterial Activity of Molecular Hybrids and Conjugates Bearing Imidazole Moiety

2020

The rapid growth of serious infections caused by antibiotic resistant bacteria, especially the nosocomial ESKAPE pathogens, has been acknowledged by Governments and scientists and is one of the world’s major health problems. Various strategies have been and are currently investigated and developed to reduce and/or delay the bacterial resistance. One of these strategies regards the design and development of antimicrobial hybrids and conjugates. This unprecedented critical review, in which our continuing interest in the synthesis and evaluation of the bioactivity of imidazole derivatives is testified, aims to summarise and comment on the results obtained from the end of the 1900s until Februa…

imidazoles molecular hybrids molecular conjugates antibacterials antibiotic resistance synthesis bioactivity antibioticsantibiotic resistancesynthesismedicine.drug_classAntibioticsPharmaceutical ScienceReviewMicrobial Sensitivity Tests010402 general chemistry01 natural sciencesantibioticsAnalytical Chemistrylcsh:QD241-441chemistry.chemical_compoundAntibiotic resistancelcsh:Organic chemistryDrug DiscoveryDrug Resistance BacterialmedicineImidazoleMoietyPhysical and Theoretical Chemistryantibacterialsmolecular conjugatesBacteria010405 organic chemistrymolecular hybridsOrganic ChemistryImidazolesSettore CHIM/06 - Chimica OrganicaBacterial InfectionsAntimicrobialCombinatorial chemistrySettore CHIM/08 - Chimica Farmaceutica0104 chemical sciencesAnti-Bacterial AgentschemistryChemistry (miscellaneous)bioactivityMolecular MedicineAntibacterial activityLinkerConjugateMolecules
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Moving RTS/CTS to the frequency domain: an efficient contention scheme for 802.11ax networks

2019

In this paper, we propose a contention mechanism based on the execution of multiple contention rounds in the frequency domain (ReCHo), which is designed to offer high throughput performance and robustness with respect to imperfect carrier sensing. The main idea is using narrow tones as signalling messages for performing channel access contentions and allowing the Access Point (AP) to echo these signals, in order to extend the sensing capabilities to all the stations associated to the AP. In particular, we refer to the emerging IEEE 802.11ax standard, showing how our scheme can boost performance of random access with respect to the current version of IEEE 802.11ax OFDMA Back-Off (OBO), even …

imperfect sensingHidden node problemSettore ING-INF/03 - TelecomunicazioniOrthogonal frequency-division multiplexingComputer sciencebusiness.industryMechanism based020206 networking & telecommunications02 engineering and technologySignallingFrequency-domain signallingRobustness (computer science)020204 information systemsFrequency domainTelecommunications link0202 electrical engineering electronic engineering information engineeringfrequency-domain signalling; IEEE 802.11ax; imperfect sensing; random access contentionrandom access contentionbusinessIEEE 802.11axRandom accessComputer network
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Host Developmental Stage Effects on Parasite Resistance and Tolerance.

2022

Hosts can defend themselves against parasites either by preventing or limiting infections (resistance) or by limiting parasite-induced damage (tolerance). However, it remains underexplored how these defense types vary over host development with shifting patterns of resource allocation priorities. Here, we studied the role played by developmental stage in resistance and tolerance in Atlantic salmon (Salmo salar). This anadromous fish has distinct life stages related to living in freshwater and seawater. We experimentally exposed 1-year-old salmon, either at the freshwater stage or at the stage transitioning to the marine phase, to the trematode Diplostomum pseudospathaceum. Using 56 pedigree…

imumadotFresh WaterparasitismiatlantinlohiresistenssielinkiertoFish DiseasesisäntäeläimetAnimalsParasitesSeawaterTrematodaEcology Evolution Behavior and SystematicssietokykyThe American naturalist
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Evolutionary ecology of complex life cycle parasites : from genotypes to species assemblages

2012

imumadotparasitismpopulation geneticsDiplostomum pseudospathaceummultiple genotype infectionloisyhteisötphenotypic variationparasitismigenotyyppiyhteisinfektiotelinkiertopopulaatiogenetiikkaloisetlife cyclefenotyyppiTrematodacommunity structure
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Metropolin hyvinvointi

2010

innovaatiopolitiikkakaupungitkestävä kehityssosiaaliset innovaatiothyvinvointiseutuyhteistyösuurkaupungitkaupallistamismalliinnovaatiotpalvelurakenneelinkeinopolitiikkapääkaupunkiseutukunnatkumppanuusyhteistoimintayhdyskuntarakennekehitysmetropolialueetHelsinkijulkiset palvelutaluepolitiikkaUusimaa
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Cellular factors promoting efficient baculovirus internalization and gene delivery into human cells

2013

integriinitreseptoritechovirus-1integrinvirus internalizationelinkiertobakuloviruksetendocytosissyndekaanitECHO-viruksetBaculovirusendosytoosiinternalisaatiosyndecan
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History Matters: Colonial‑Based Connectivity and Foreign Headquarter Location Choice

2022

AbstractIn this study, we argue that European countries’ extensive relationships with former colonies represent a location factor that attracts foreign headquarter investments. The strategic role of foreign headquarters as coordinators, opportunity detectors, and global bridgeheads makes the location choice of headquarter activities sensitive to historical-based institutional connections. Drawing on a sample of 2230 foreign headquarter investments in Europe, we find that the stronger the combined effect of historical connections and current economic relationships with former colonies, the higher the probability of attracting headquarter investment projects. We refer to this combined charact…

intermediate headquarterscolonial linksStrategy and Managementforeign direct investmentinstitutionslocation choiceBusiness and International Managementforeign headquartersUNESCO::CIENCIAS ECONOMICAS
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One Dimensional Convolutional Neural Networks for Seizure Onset Detection Using Long-term Scalp and Intracranial EEG

2021

Epileptic seizure detection using scalp electroencephalogram (sEEG) and intracranial electroencephalogram (iEEG) has attracted widespread attention in recent two decades. The accurate and rapid detection of seizures not only reflects the efficiency of the algorithm, but also greatly reduces the burden of manual detection during long-term electroencephalogram (EEG) recording. In this work, a stacked one-dimensional convolutional neural network (1D-CNN) model combined with a random selection and data augmentation (RS-DA) strategy is proposed for seizure onset detection. Firstly, we segmented the long-term EEG signals using 2-sec sliding windows. Then, the 2-sec interictal and ictal segments w…

intracranial electroencephalogram (iEEG)convolutional neural networks (CNN).signaalinkäsittelyscalp electroencephalogram (sEEG)epilepsyseizure detectionsignaalianalyysineuroverkotEEGepilepsia
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Intrinsic spin-orbit interaction in diffusive normal wire Josephson weak links: Supercurrent and density of states

2015

We study the effect of the intrinsic (Rashba or Dresselhaus) spin-orbit interaction in superconductor--nanowire--superconductor (SNS) weak links in the presence of a spin-splitting field that can result either from an intrinsic exchange field or the Zeeman effect of an applied field. We solve the full non-linear Usadel equations numerically and analyze the resulting supercurrent through the weak link and the behavior of the density of states in the center of the wire. We point out how the presence of the spin-orbit interaction gives rise to a long-range spin triplet supercurrent, which remains finite even in the limit of very large exchange fields. In particular, we show how rotating the fi…

intrinsic spin-orbit interactionField (physics)ta221Josephson weak linksFOS: Physical sciences02 engineering and technologysuperconductors01 natural sciencesSuperconductivity (cond-mat.supr-con)symbols.namesakeCondensed Matter::SuperconductivityQuantum mechanics0103 physical sciences010306 general physicssupercurrentSpin-½SuperconductivityPhysicsZeeman effectta114Condensed matter physicsCondensed Matter - SuperconductivitySupercurrentSpin–orbit interactionCondensed Matter::Mesoscopic Systems and Quantum Hall Effect021001 nanoscience & nanotechnologynanowiresPairingDensity of statessymbols0210 nano-technologyPhysical Review B
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Preparation of Polymeric Nanoparticles by Photo-Crosslinking of an Acryloylated Polyaspartamide in w/o Microemulsion

2004

Biodegradable polymeric nanoparticles have been prepared by UV irradiation of an acryloylated water soluble polymer by an inverse microemulsion. The starting polymer was a α,β‐poly(N‐2‐hydroxyethyl)‐D,L‐aspartamide (PHEA) partially functionalized with glycidyl methacrylate (GMA) in order to introduce reactive vinyl groups in the side chain. The PHEA‐GMA copolymer obtained (PHG) was crosslinked by UV irradiation of the inverse microemulsion prepared by mixing an aqueous solution of PHG with propylene carbonate (PC)/ethyl acetate (EtOAc) in the presence of sorbitan trioleate (SPAN 85) as surfactant. Nanoparticles obtained were characterized by FTIR spectrophotometry, transmission electron mic…

inverse microemulsionGlycidyl methacrylatePHGAqueous solutionPolymers and PlasticsChemistryOrganic ChemistryNanoparticleCondensed Matter Physicsacryloylated polyaspartamide inverse microemulsion irradiation nanoparticles PHG photo‐crosslinkingphoto-crosslinkingchemistry.chemical_compoundSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoPolymer chemistryMaterials ChemistryZeta potentialSide chainCopolymernanoparticlesMicroemulsionPhysical and Theoretical ChemistryDrug carrieracryloylated polyaspartamideMacromolecular Chemistry and Physics
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