Search results for "load"
showing 10 items of 1967 documents
Peginterferon alfa-2b plus weight-based ribavirin for 24 weeks in patients with chronic hepatitis C virus genotype 1 with low viral load who achieve …
2011
Summary. In chronic hepatitis C (CHC), treatment duration may be individualized according to time to first undetectable hepatitis C virus (HCV) RNA, with patients who attain undetectable HCV RNA early in treatment being candidates for shorter regimens. The aim of this study was to determine the relapse rate in patients with CHC genotype (G) 1 infection and low baseline viral load who achieved undetectable HCV RNA by week 4 [rapid virologic response (RVR)] when treated for 24 weeks. This was an open-label, multicentre, noninterventional study. Adult patients with G1 CHC infection and baseline viral load <600,000 IU/mL who attained RVR were treated with peginterferon alfa-2b (1.5 μg/kg/week)…
Usefulness and limitations of contractile reserve evaluation in patients with low-flow, low-gradient aortic stenosis eligible for cardiac resynchroni…
2014
Aims In low-flow, low-gradient aortic stenosis (LF/LG AS), the assessment of contractile reserve (CR) by dobutamine stress echocardiography (DSE) is recommended for risk stratification and treatment strategy. However, DSE may show limitations in cases of left ventricular dyssynchrony (LVD). The impact of LVD in LF/LG AS, and the feasibility of CRT in this setting have never been evaluated. We aimed to assess: (i) the proportion of LF/LG AS patients with LVD; (ii) the influence of LVD on CR at DSE; and (iii) the effects of CRT in these patients. Methods and results Thirty consecutive patients with LF/LG AS underwent DSE with study of CR. The operative risk for aortic valve replacement (AVR) …
Effects of workload level on muscle recruitment in cycling
2014
AbstractPurpose. Despite the volume of studies addressing muscle activation during pedaling, it is unclear whether changes in workload level during cycling could dictate motor unit recruitment. The present study investigated the frequency content of lower limb muscle activation during submaximal workloads. Methods. Twelve male competitive cyclists pedaled at three workload levels: (1) maximum aerobic power output (PO
The Impact of the COVID-19 Pandemic on ICU Healthcare Professionals: A Mixed Methods Study
2021
The large numbers of patients admitted to intensive care units due to COVID-19 has had a major impact on healthcare professionals. The incidence of mental health disorders among these professionals has increased considerably and their professional quality of life has suffered during the pandemic. This study aims to explore the impact of the provision of COVID-19 patient care on ICU healthcare professionals. A mixed methods study with an exploratory concurrent design was conducted between June and November 2020 in the Balearic Islands, Spain. Data were collected using a self-report online survey (n = 122) based on three validated questionnaires, and individual semi-structured in-depth online…
Experiences of people with memory disorders and their spouse carers on influencing formal care: “They ask my wife questions that they should ask me”
2021
Background People with memory disorders often need care and help from family carers and health and social care providers. Due to the deterioration of cognitive capacity and language skills, they may be unable to convey their thoughts and care preferences to other people. As a result, their agency may become restricted. We investigated the descriptions provided by people with memory disorders and spousal carers of their influence on care in encounters with formal care providers. Methods Qualitative thematic analysis was used to identify, analyze, and report themes that describe encounters with professionals in different social or healthcare environments. In-depth interview data were gathered…
Differences in cytomegalovirus plasma viral loads measured in allogeneic hematopoietic stem cell transplant recipients using two commercial real-time…
2010
5 páginas, 3 figuras.
Influence of the prosthetic arm length (palatal position) of zygomatic implants upon patient satisfaction
2016
Background: To assess the influence of the prosthetic arm length (palatal position) of zygomatic implants upon patient comfort and stability, speech, functionality and overall satisfaction. Material and Methods: A retrospective clinical study was made of patients subjected to rehabilitation of atrophic maxilla with complete maxillary implant-supported fixed prostheses involving a minimum of two zygomatic implants (one on each side) in conjunction with premaxillary implants, and with 12 months of follow-up after implant loading. Subjects used a VAS to score general satisfaction, comfort and stability, speech and functionality, and the results were analyzed in relation to the prosthetic arm l…
Käsitteellinen ymmärtäminen ja fysiikan oppimiseen liittyvät odotukset lukion mekaniikassa
2018
Aikaisempi tutkimus (Utriainen 2004) ja myöhempi oppimistulosten tarkastelu paljastivat puutteita, jotka koskivat kappaleen liiketilan ja kappaleen vuorovaikutusten välisen yhteyden ymmärrystä. Voimakuvion laadinta ja liikeyhtälön kirjoittaminen tuottivat vaikeuksia. Pakollisella fysiikan kurssilla opiskelijat muodostavat käsityksen, joka koskee fysiikkaa oppiaineena ja sen opiskelua. Saaduilla kokemuksilla voi olla merkitystä fysiikan syventäviin kursseihin kohdistuviin odotuksiin. Opetukselle asetettiin kaksi tavoitetta: piti edistää Newtonin toiseen ja Newtonin kolmanteen lakiin liittyvien tehtävien kvalitatiivista osaamista ja liikeyhtälön kirjoittamista sekä yrittää vaikuttaa opiskelij…
Increased fascicle length but not patellar tendon stiffness after accentuated eccentric-load strength training in already-trained men
2020
Purpose This study examined whether additional external load during the eccentric phase of lower limb strength training exercises led to greater adaptations in knee extensor strength, muscle architecture, and patellar tendon properties than traditional concentric–eccentric training in already-trained men. Methods Twenty-eight men accustomed to strength training were randomized to undertake 10 weeks of supervised traditional (TRAD) or accentuated eccentric loading (AEL) or continue their habitual unsupervised (CON) strength training. TRAD and AEL trained 2∙week−1 with a six-repetition maximum (RM) session and a ten-RM session. TRAD used the same external load in both concentric and eccentric…
Prediction of harmful variants on mitochondrial genes : Test of habitat-dependent and demographic effects in a euryhaline fish
2017
Both effective population size and life history may influence the efficacy of purifying selection, but it remains unclear if the environment affects the accumulation of weakly deleterious nonsynonymous polymorphisms. We hypothesize that the reduced energetic cost of osmoregulation in brackish water habitat may cause relaxation of selective constraints at mitochondrial oxidative phosphorylation (OXPHOS) genes. To test this hypothesis, we analyzed 57 complete mitochondrial genomes of Pungitius pungitius collected from brackish and freshwater habitats. Based on inter- and intraspecific comparisons, we estimated that 84% and 68% of the nonsynonymous polymorphisms in the freshwater and brackish …