Search results for "load"

showing 10 items of 1967 documents

Early neutralizing and glycoprotein B (gB)-specific antibody responses to human cytomegalovirus (HCMV) in immunocompetent individuals with distinct c…

2000

Abstract Background: Antibodies with functional anti-Human Cytomegalovirus (HCMV) activity are likely to be involved in preventing virus dissemination and thus may contribute to minimize the clinical manifestations of infection. Objectives: To investigate the role of humoral immunity in modulating the clinical expression of primary Human Cytomegalovirus (HCMV) infection in immunocompetent persons. Study design: Neutralizing (NA) and glycoprotein B (gB)-specific antibodies were quantitated in acute-phase and late-convalescence phase sera from 19 individuals who developed either HCMV mononucleosis (12) or oligosymptomatic hepatitis (seven). Results: The levels of NA in sera drawn early after …

AdultMaleHuman cytomegalovirusAdolescentHepatitis Viral HumanMononucleosisvirusesAntibody AffinityCongenital cytomegalovirus infectionBiologyAntibodies ViralViral Envelope ProteinsNeutralization TestsVirologymedicineHumansAvidityInfectious MononucleosisChildmedicine.diseaseVirologyInfectious DiseasesChild PreschoolImmunoglobulin GCytomegalovirus InfectionsDNA ViralHumoral immunityImmunologybiology.proteinFemaleAntibodyViral hepatitisImmunocompetenceViral loadJournal of Clinical Virology
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Antibody response to human cytomegalovirus (HCMV) glycoprotein B (gB) in AIDS patients with HCMV end-organ disease

1998

Human cytomegalovirus (HCMV)-specific antibody responses in HIV-1 infected individuals either with or without HCMV end-organ disease were examined to determine the whether development of HCMV disease was associated with a particular deficit in the antibody response. Antiwhole HCMV, anti-glycoprotein B (gB), and neutralizing antibody levels were higher in HIV-1 infected individuals than in healthy immunocompetent subjects, particularly in patients with AIDS either with or without HCMV-associated disease. Irrespective of location and spread of HCMV disease, patients who had received anti-HCMV therapy prior to sampling exhibited significantly higher anti-gB and neutralizing antibody titers tha…

AdultMaleHuman cytomegalovirusAdolescentvirusesCytomegalovirusBiologyAntibodies ViralAntiviral AgentsViral Envelope ProteinsNeutralization TestsBetaherpesvirinaeVirologyImmunopathologymedicineHumansViremiaFluorescent Antibody Technique IndirectNeutralizing antibodyAcquired Immunodeficiency SyndromeAIDS-Related Opportunistic InfectionsAntibody titervirus diseasesbiochemical phenomena metabolism and nutritionmedicine.diseasebiology.organism_classificationVirologyCD4 Lymphocyte CountInfectious DiseasesImmunoglobulin GCytomegalovirus InfectionsImmunologyHIV-1biology.proteinFemaleViral diseaseAntibodyViral loadJournal of Medical Virology
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The facilitative effect of gestures on the neural processing of semantic complexity in a continuous narrative

2019

© 2019 Elsevier Inc. Gestures are elemental components of social communication and aid comprehension of verbal messages; however, little is known about the potential role of gestures in facilitating processing of semantic complexity in an ecologically valid setting. The goal of this study was to investigate whether cognitive load, as indexed by semantic complexity, is modulated by the presentation of gestures accompanying speech. Twenty healthy participants watched 16 video clips of a short narrative while instructed to carefully listen to and watch the narrator while functional magnetic resonance imaging (fMRI) data were acquired. The videos contained passages with and without various co-s…

AdultMaleIdea densityComputer scienceCognitive Neuroscience050105 experimental psychology03 medical and health sciencesYoung Adult0302 clinical medicineDiscourse perceptionmedicineSemantic memoryHumansPsychology0501 psychology and cognitive sciencesNarrativeSemantic complexityDefault mode networkTemporal cortexmedicine.diagnostic_testGestures05 social sciencesNeurosciencesBrainMagnetic Resonance ImagingSemanticsNeurologySpeech PerceptionDefault mode networkFemaleFunctional magnetic resonance imagingComprehension030217 neurology & neurosurgeryCognitive loadCognitive psychologyGestureCo-speech gestures
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Maintenance of marginal bone support and soft tissue esthetics at immediately provisionalized OsseoSpeed implants placed into extraction sites: 2-yea…

2012

Background Placement of implants into extraction sockets targets the maintenance of peri-implant hard and soft tissue structures and the support of a natural and esthetic contour. The main advantages of immediate implant insertion in comparison with delayed implant placement protocols are as follows: a reduced treatment time, less number of sessions, and, thus, the less invasive procedure. This study examines the clinical performance (survival rate, marginal bone levels and Pink Esthetic Score [PES]) of OsseoSpeed™ implants placed into extraction sockets with immediate provisionalization in the anterior maxilla after a follow-up of at least 12 months. Methods Twenty patients received a tota…

AdultMaleImmediate Dental Implant LoadingFacial boneEstheticsmedicine.medical_treatmentAlveolar Bone LossDentistryProsthesisDental Implants Single-ToothAlveolar ProcessMedicineHumansProspective StudiesTooth SocketSurvival rateAgedbusiness.industryAlveolar processClinical performanceSoft tissueMiddle AgedImmediate provisionalizationmedicine.anatomical_structureTreatment OutcomeDental Prosthesis DesignFemaleImplantOral SurgerybusinessClinical oral implants research
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Clinical and esthetic outcome with immediate insertion and provisionalization with or without connective tissue grafting in presence of mucogingival …

2017

Background Recessions following immediate implant insertion are frequently reported in the literature. Data regarding implant installation in presence of mucogingival recessions are rare. Purpose This study observes soft tissue level changes following immediate implant insertion and provisionalization of implants with or without connective tissue grafts in the anterior maxilla in patients with initial mucogingival recession within a follow-up period between one and eight years. Materials and methods Twenty-six patients with marginal gingival recessions, which were designated for extraction and immediate implant insertion in the anterior zone of the maxilla (13-23), were included. Out of a l…

AdultMaleImmediate Dental Implant LoadingFacial boneGingivaDentistryConnective tissueEsthetics DentalTransplantation AutologousYoung Adult03 medical and health sciencesDental Implants Single-Tooth0302 clinical medicineGermanyMaxillaRetrospective analysisHumansPeriodontal PocketMedicineGingival RecessionGeneral DentistryAgedRetrospective StudiesDental ImplantsBone Transplantationbusiness.industrySoft tissue030206 dentistrySingle toothCone-Beam Computed TomographyMiddle AgedAutologous boneIncisorTreatment Outcomemedicine.anatomical_structureDental Prosthesis DesignConnective Tissue030220 oncology & carcinogenesisMaxillaTooth ExtractionFemaleDental Prosthesis Implant-SupportedImplantOral SurgerybusinessFollow-Up StudiesClinical Implant Dentistry and Related Research
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Immediately provisionalized OsseoSpeed(™) Profile implants inserted into extraction sockets: 3-year results.

2015

Objectives A sloped shoulder might improve the congruence between extraction socket and dental implant and may add to a better circumferential support of the peri-implant structures. Therefore, this study evaluates the 3-year clinical outcome (survival and success rates, marginal bone levels, and Pink Esthetic Score (PES)) of immediately inserted and provisionalized OsseoSpeed(™) Profile implants in the anterior maxilla. Material and methods Twenty-one implants were inserted in 16 patients. All implants were immediately placed into extraction sites with and without facial bone deficiencies. A flapless procedure was utilized, and the implants were provisionalized immediately. Facial gaps wer…

AdultMaleImmediate Dental Implant LoadingFacial boneRadiographymedicine.medical_treatmentAnterior maxilla0206 medical engineeringDentistry02 engineering and technologyMandibleBone grafting03 medical and health sciences0302 clinical medicinemedicineHumansProspective StudiesAutogenous boneTooth SocketDental implantAgedDental ImplantsBone Transplantationbusiness.industrySoft tissue030206 dentistryMiddle Aged020601 biomedical engineeringTreatment OutcomeDental Prosthesis DesignFemaleImplantOral SurgerybusinessClinical oral implants research
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Survival rates and bone loss after immediate loading of implants in fresh extraction sockets (single gaps). A clinical prospective study with 4 year …

2016

Background The aim of this prospective study was to report the outcome of treatment with implants inserted after tooth extraction and immediately loaded. Material and Methods Fifty-six patients with single tooth loss were treated with 116 IPX Galimplant® implants with internal connections and a sandblasted, acid-etched surface. All implants were placed after tooth extraction using a flapless approach without bone regeneration, and they were then immediately loaded with cemented acrylic prostheses. After a period of three months, definitive cemented ceramic prostheses were placed. Patients were examined throughout a total of 4 years of follow-up. Marginal bone loss and survival rates were ev…

AdultMaleImmediate Dental Implant LoadingTime FactorsAlveolar Bone LossDentistry03 medical and health sciencesDental Implants Single-Tooth0302 clinical medicinemedicineHumansDental Restoration FailureProspective Studies030212 general & internal medicineTooth SocketProspective cohort studyBone regenerationGeneral DentistryDental alveolusPeriodontitisbusiness.industryResearchMandible030206 dentistrySingle toothMiddle Aged:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseTreatment OutcomeOtorhinolaryngologyMaxillaUNESCO::CIENCIAS MÉDICASTooth ExtractionFemaleSurgeryImplantOral SurgerybusinessFollow-Up StudiesMedicina Oral Patología Oral y Cirugia Bucal
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Optimized threshold for serum HCV RNA to predict treatment outcomes in hepatitis C patients receiving peginterferon alfa-2a/ribavirin

2012

It is unclear whether the current threshold for 'high' hepatitis C virus (HCV) RNA level (800,000 IU/mL) is optimal for predicting sustained virological response (SVR). We retrospectively analysed pretreatment HCV RNA levels and SVR rates in 1529 mono-infected and 176 HIV-HCV co-infected patients treated with peginterferon alfa-2a (40 kD) plus ribavirin. We improved the threshold for differentiating low and high viral load by fitting semiparametric generalized additive logistic regression models to the data and constructing receiver operating characteristics curves. Among HCV genotype 1 mono-infected patients, the difference in SVR rates between those with low and high baseline HCV RNA leve…

AdultMaleInterferon-alphaAlanine TransaminaseHepacivirusMiddle AgedViral LoadAntiviral AgentsHepatitis CRecombinant ProteinsPolyethylene GlycolsLogistic ModelsTreatment OutcomeROC CurveRibavirinHumansRNA ViralDrug Therapy CombinationFemalehepatitis CRetrospective Studies
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Perceived collective burnout: a multilevel explanation of burnout

2011

Building up on the socially induced model of burnout and the job demands-resources model, we examine how burnout can transfer without direct contagion or close contact among employees. Based on the social information processing approach and the conservation of resources theory, we propose that perceived collective burnout emerges as an organizational-level construct (employees' shared perceptions about how burned out are their colleagues) and that it predicts individual burnout over and above indicators of demands and resources. Data were gathered during the first term and again during the last term of the academic year among 555 teachers from 100 schools. The core dimensions of burnout, ex…

AdultMaleInterprofessional RelationsApplied psychologyWorkloadBurnoutJob SatisfactionSocial information processingCynicismArts and Humanities (miscellaneous)Surveys and QuestionnairesDevelopmental and Educational PsychologyHumansWorkplaceBurnout ProfessionalSocial perceptionMultilevel modelSocial SupportWorkloadMiddle AgedFacultyPsychiatry and Mental healthClinical PsychologySocial PerceptionAbsenteeismFemaleJob satisfactionPsychologyAttitude to HealthSocial psychologyAnxiety, Stress & Coping
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MR imaging technique for the diagnosis of pituitary iron overload in patients with transfusion-dependent beta-thalassemia major

1998

To identify the optimal MR imaging technique for diagnosing pituitary iron overload, we compared spin-echo and gradient-echo MR imaging with measurements of pituitary T2 relaxation times in 30 patients with secondary hemochromatosis due to transfusion-dependent beta-thalassemia major and in 10 healthy volunteers. We found that the optimal MR imaging technique to evaluate pituitary iron overload is the gradient-echo T2*-weighted technique, as it best demonstrated signal reduction in the anterior lobe of the pituitary gland.

AdultMaleIron OverloadAdolescentPituitary Glandbeta-ThalassemiaJournal ArticleHumansTransfusion ReactionBlood TransfusionFemaleMagnetic Resonance ImagingHuman
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