Search results for "lobo"

Segregation and co-occurrence of larval cestodes in freshwater fishes in the Bothnian Bay, Finland

1992

SUMMARYTwo autogenic (Triaenophorus crassus and T. nodulosus) and four allogenic (Diphyllobothrium latum, D. dendriticum, D. ditremum and Schistocephalus solidus) larval cestode species were found in 13 out of 31 fish species studied from the Bothnian Bay, NE Baltic. Gasterosteus aculeatus was the most heavily infected fish with 4 larval cestode species; for two of them (D. ditremum and S. solidus) the three-spined stickleback was found to be the required fish intermediate host. Among allogenic cestode species, those restricted to different definitive host species segregated their larval population in relation to the fish host, while, for example, D. ditremum and S. solidus, both maturing i…

Tantas caperucitas como lobos

2007

Caperucita Roja es un cuento que se origina como relato oral en Francia mucho antes de que Perrault lo normalizara en su libro Contes de Ma Mere L'Oye publicado en 1697. A través de su evolución en el tiempo Caperucita invade otros géneros además del literario. El cine, la fotografía, la ilustración, reinterpretan la relación entre la joven y el lobo desde el impresionismo al psicoanálisis pasando por las relaciones de estructura social, etc. En ocasiones los textos originales requieren de una posterior lectura al encontrar en la imagen pictórica y/o fotográfica nuevas interpretaciones.

La construcción de la imagen de la mujer en el humor gráfico del semanario de humor Hermano Lobo (1972 - 1976)

2014

La construcción de la imagen de la mujer en el humor gráfico del semanario de humor Hermano Lobo (1972 - 1976)

Fabry Disease, a Complex Pathology Not Easy to Diagnose

2015

Fabry disease is a multisystemic lysosomal storage disorder, inherited in an X-linked manner. It is a defect of metabolism of the glycosphingolipids, due to the reduction or absence of the activity of lysosomal enzyme α-galactosidase A. This reduction of activity causes the storage of globotriaosylceramide and derivatives in the lysosomes, triggering a cascade of cellular events, mainly in vascular endothelium. These events are the responsible for the systemic clinical manifestations and the renal, cardiac and cerebrovascular complications, or a combination of them. The symptomatology can lead to the premature death of patient between the fourth or fifth decade of life. The first symptoms c…

A classical phenotype of Anderson-Fabry disease in a female patient with intronic mutations of the GLA gene: a case report

2012

Abstract Background Fabry disease (FD) is a hereditary metabolic disorder caused by the partial or total inactivation of a lysosomal hydrolase, the enzyme α-galactosidase A (GLA). This inactivation is responsible for the storage of undegraded glycosphingolipids in the lysosomes with subsequent cellular and microvascular dysfunction. The incidence of disease is estimated at 1:40,000 in the general population, although neonatal screening initiatives have found an unexpectedly high prevalence of genetic alterations, up to 1:3,100, in newborns in Italy, and have identified a surprisingly high frequency of newborn males with genetic alterations (about 1:1,500) in Taiwan. Case presentation We des…

Downregulation of alpha-galactosidase A upregulates CD77: functional impact for Fabry nephropathy.

2009

Anderson-Fabry disease, an inherited deficiency in the lysosomal enzyme alpha-galactosidase A, is characterized by the progressive accumulation of globotriaosylceramide (Gb3), also known as CD77. We sought to clarify the pathogenesis of Fabry disease by establishing a cell model of this disorder. The expression of alpha-galactosidase A was transiently silenced by RNA interference in HK2 and primary human renal epithelial cells and stably silenced in HK2 cells by retroviral transfection with small hairpin RNA. All of the silenced cells had histological similarities to cells of patients with Fabry disease. The cells had reduced viability, significant accumulation of intracellular Gb3, and a m…

Effects of enzyme replacement therapy with agalsidase alfa on glomerular filtration rate in patients with Fabry disease: preliminary data

2007

Progressive deposition of globotriaosylceramide results in severe complications involving the kidney, heart and brain in both hemizygous male and heterozygous female patients with Fabry disease. Analysis of renal data from FOS - the Fabry Outcome Survey - suggests that enzyme replacement therapy with agalsidase alfa can significantly improve renal function in patients with Fabry disease, at least in those with a mild decrease in glomerular filtration rate, and may also be able to slow down the natural decline in renal function in patients with a moderate reduction in glomerular filtration rate. Conclusion: Initial results from the large cohort of patients within FOS indicate that treatment …

Oral findings in Midline Syndrome: a case report and literature review

2010

We describe a female patient with a midline syndrome. The patient presents agenesis of the corpus callosum, encephalocele, iris coloboma, hypertelorism, submucosal cleft palate and dental anomalies. Despite being very characteristic, her phenotypical traits do not coincide exactly with those reported to date in the literature. The karyotype and the molecular cytogenetic study do not show mutations. We identify the presence of dental anomalies in the mother and other family members, not being identified MSX1 and PAX9 mutations that could the related with their etiology. Despite the fact that dental agenesis has been related to a large number of other malformation syndromes and congenital con…

A study of plasma and urinary sediment globotriaosylceramide levels in females with Fabry disease

2007

La caracterización de Fadrique (Fadrique Furio Ceriol) en la Philosophia Antigua Poética de Alonso López Pinciano

2021

Abordamos en este trabajo la caracterización del personaje de Fadrique en la Philosophia Antigua Poetica y su identificación con el humanista valenciano Fadrique Furio Ceriol. A través de esta caracterización nos aproximaremos a los rasgos personales y vitales, sus actividades y participación en algún círculo literario en los últimos 10 años de su vida. In this work we address the characterization of the character of Fadrique in the Philosophia Antigua Poetica and his identification with the Valencian humanist Fadrique Furio Ceriol. Through this characterization we will approach his personal and vital traits, his activities and his proximity to a literary circle in the last 10 years of his …