Search results for "localization"

showing 10 items of 443 documents

Changes in immunohistochemical levels and subcellular localization after therapy and correlation and colocalization with CD68 suggest a pathogenetic …

2011

In an earlier work, the role of heat shock protein (Hsp60) in the pathogenesis of ulcerative colitis (UC) was suggested by its significant increase in the pathological mucosa parallel with an increase in inflammatory cells. More data in this direction are reported in this work. We analyzed by immunohistochemistry biopsies of colon tissue from 2 groups of patients with UC and treated with either 5-aminosalicylic acid (5-ASA) alone or in combination with a probiotic. We looked for inflammatory markers and Hsp60. Both the treatments were effective in reducing symptoms but the group treated with both 5-ASA and probiotics showed better clinical results. Amelioration of symptoms was associated wi…

Pathologymedicine.medical_specialtyHistologyColonBiopsyAntigens Differentiation MyelomonocyticInflammationBiomarkers PharmacologicalPathology and Forensic MedicinePathogenesisAntigens CDHeat shock proteinmedicineHumansColitisMesalamineInflammationMucous Membranebusiness.industryCD68ProbioticsAnti-Inflammatory Agents Non-SteroidalColocalizationChaperonin 60medicine.diseaseUlcerative colitisImmunohistochemistryMedical Laboratory TechnologyProtein TransportGene Expression RegulationDisease ProgressionImmunohistochemistryColitis Ulcerativemedicine.symptombusinessFollow-Up StudiesApplied immunohistochemistrymolecular morphology : AIMM
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Building a State’s Global Competitive Advantage by Improving Its Finances: A System Dynamic Model Tailored for the Italian State

2014

The present study analyzes and tests a new way to recover economy and public finances in time of crisis. An exclusive focus on State financial short-term stability risks to undermine the economic growth and to erode the social environment, thus it depletes the sources of State finances on the long-term. While a sustainable strategizing focuses on performance drivers that generate these last. Such approach in public strategizing is based on the assumption that State could increase its budgets by improving the organizational and legal framework in which private firms operate, in order to reduce their overhead costs for compliance of rules, and public facilities’ inefficiencies. This improveme…

Performance management delocalization sustainability financial strategy Italy System dynamics
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Understanding the mechanism of non-polar diels-alder reactions. A comparative elf analysis of concerted and stepwise diradical mechanisms

2010

The electron-reorganization along the concerted and stepwise pathways associated with the non-polar Diels-Alder reaction between cyclopentadiene (Cp, 1) and ethylene (2) has been studied using the topological analysis of the electron localization function (ELF) at the B3LYP/6-31G(d) level of theory. ELF results for the concerted mechanism stresses that the electron-reorganization demanded on the diene and ethylene reagents to reach two pseudo-diradical structures is responsible for the high activation energy. A comparative ELF analysis of some relevant points of the non-polar Diels-Alder reaction between Cp and styrene (10) suggests that these concerted mechanisms do not have a pericyclic e…

Pericyclic reactionEthyleneCyclopentadieneDieneDiradicalConcerted reactionStereochemistryOrganic Chemistryrespiratory systemBiochemistryElectron localization functionStyrenechemistry.chemical_compoundchemistryPhysical and Theoretical Chemistry
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Azo-hydrazo conversion via [1,5]-hydrogen shifts. A combined experimental and theoretical study

2012

Abstract Azoalkenes 6e , 6g , 6h , and 8c underwent an easy azo-hydrazo conversion via a [1,5]-hydrogen shift yielding α,β-unsaturated hydrazones. The isomerization products were characterized through spectroscopic and spectrometric techniques. In order to understand the nature of the mechanism of these [1,5]-hydrogen shifts, the transition state structures of the reactions were theoretically studied at the B3LYP/6-31G(d,p) level. Substitution effects in the propenylazo system on the kinetic and thermodynamic parameters were analyzed. An electron localization function (ELF) analysis of the electronic structure of the transition state structure associated with the azo-hydrazo conversion of t…

Pericyclic reactionHydrogenChemistryOrganic Chemistrychemistry.chemical_elementElectronic structureHydrogen atomKinetic energyBiochemistryTransition stateElectron localization functionComputational chemistryDrug DiscoveryIsomerizationTetrahedron
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Comparative Structural Studies of 4-Diazopyrazole Derivatives by X-Ray Diffraction and Theoretical Investigation

2005

The X-Ray crystal and molecular structures of the 4-pyrazol derivatives 3-methyl-4-diazo-5-benzamido-1H-pyrazole (4) and 3-benzamido-5-methyl-1H-pyrazole (3) have been determined. A dimeric structure has been found for the first and polymeric for the second. A comparison of 4 with 1,3-dimethyl-4-diazo-5-benzamido-lH-pyrazole (2) shows differences in the geometrical parameters of the pyrazole ring due to electron delocalization in 2 consequent to the nitrogen negative charge in the latter. Theoretical investigation at the density functional theory (DFT) level shows difference in the molecular electronic distribution of 2 and 4, in agreement with the structural parameters and the IR stretchin…

PharmacologyChemistryOrganic ChemistryElectron delocalizationPyrazoleRing (chemistry)Analytical ChemistryCrystalCrystallographychemistry.chemical_compoundNegative chargeX-ray crystallographyX-Ray crystal molecular structures derivativesDensity functional theory
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When are thin films of metals metallic? Part III

1996

Abstract A large amount of experimental information has indicated that very thin films of metallic elements can exhibit nonmetallic behavior, even on metal substrates. These films undergo a gradual nonmetal to metal transition with increasing film density or thickness. The nonmetallic behavior can be related to electron localization due to strong electron-electron correlation in low dimensional systems, as indicated by the strong enhancement of electron effective mass. The evolution in the electronic structure associated with the nonmetal to metal transition bears a striking resemblance to the behavior observed for free metal clusters. Part I [1], outlined the general concepts of a nonmetal…

Phase transitionMaterials scienceMetal K-edgeMechanical EngineeringElectronic structureCondensed Matter PhysicsElectron localization functionMetalEffective mass (solid-state physics)NonmetalMechanics of MaterialsChemical physicsvisual_artvisual_art.visual_art_mediumGeneral Materials ScienceThin filmMaterials Science and Engineering: A
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Quantum non-Markovianity induced by Anderson localization

2017

As discovered by P. W. Anderson, excitations do not propagate freely in a disordered lattice, but, due to destructive interference, they localise. As a consequence when an atom interacts with a disordered lattice one indeed observes, a non-trivial excitation exchange between atom and lattice. Such non-trivial atomic dynamics will in general be characterised also by a non-trivial quantum information backflow, a clear signature of non-Markovian dynamics. To investigate the above scenario we consider a quantum emitter, or atom, weakly coupled to a uniform coupled-cavity array (CCA). If initially excited, in the absence of disorder, the emitter undergoes a Markovian spontaneous emission by rele…

Physics---Anderson localizationQuantum PhysicsMultidisciplinaryFOS: Physical sciences01 natural sciencesArticleSettore FIS/03 - Fisica Della Materia010305 fluids & plasmasNormal modeExcited stateQuantum mechanics0103 physical sciencesPhenomenological modelAtomSpontaneous emissionQuantum information010306 general physicsQuantum Physics (quant-ph)QuantumScientific Reports
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Level statistics and Anderson delocalization in two-dimensional granular materials

2020

Contrary to the theoretical predictions that all waves in two-dimensional disordered materials are localized, Anderson localization is observed only for sufficiently high frequencies in an isotropically jammed two-dimensional disordered granular packing of photoelastic disks. More specifically, we have performed an experiment in analyzing the level statistics of normal mode vibrations. We observe delocalized modes in the low-frequency boson-peak regime and localized modes in the high frequency regime with the crossover frequency just below the Debye frequency. We find that the level-distance distribution obeys Gaussian-Orthogonal-Ensemble (GOE) statistics, i.e. Wigner-Dyson distribution, in…

PhysicsAnderson localizationFOS: Physical sciences02 engineering and technologyCondensed Matter - Soft Condensed Matter021001 nanoscience & nanotechnologyGranular material01 natural sciencesDebye frequencyDelocalized electronNormal mode0103 physical sciencesStatisticsExponentSoft Condensed Matter (cond-mat.soft)010306 general physics0210 nano-technologyScalingAnderson impurity model
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The phase diagram of the multi-dimensional Anderson localization via analytic determination of Lyapunov exponents

2004

The method proposed by the present authors to deal analytically with the problem of Anderson localization via disorder [J.Phys.: Condens. Matter {\bf 14} (2002) 13777] is generalized for higher spatial dimensions D. In this way the generalized Lyapunov exponents for diagonal correlators of the wave function, $$, can be calculated analytically and exactly. This permits to determine the phase diagram of the system. For all dimensions $D > 2$ one finds intervals in the energy and the disorder where extended and localized states coexist: the metal-insulator transition should thus be interpreted as a first-order transition. The qualitative differences permit to group the systems into two classes…

PhysicsAnderson localizationGroup (mathematics)DiagonalFOS: Physical sciencesLyapunov exponentFunction (mathematics)Disordered Systems and Neural Networks (cond-mat.dis-nn)Condensed Matter - Disordered Systems and Neural NetworksCondensed Matter PhysicsElectronic Optical and Magnetic Materialssymbols.namesakePercolationsymbolsCritical dimensionMathematical physicsPhase diagram
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What is the Right Theory for Anderson Localization of Light? An Experimental Test

2018

Anderson localization of light is traditionally described in analogy to electrons in a random potential. Within this description, the random potential depends on the wavelength of the incident light. For transverse Anderson localization, this leads to the prediction that the distribution of localization lengths---and, hence, its average---strongly depends on the wavelength. In an alternative description, in terms of a spatially fluctuating electric modulus, this is not the case. Here, we report on an experimentum crucis in order to investigate the validity of the two conflicting theories using optical samples exhibiting transverse Anderson localization. We do not find any dependence of the …

PhysicsAnderson localizationPhysics and Astronomy (all); Anderson localization of light; electronsSigma modelGeneral Physics and AstronomyElectronWave equation01 natural sciencesRayExperimentum crucis010309 opticsNonlinear systemWavelengthQuantum mechanics0103 physical sciences010306 general physicsPhysical Review Letters
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