Search results for "location"
showing 10 items of 1480 documents
Thermodynamics-based gradient plasticity theories with an application to interface models
2008
AbstractIn the framework of small deformations, the so-called residual-based gradient plasticity theory is reconsidered and improved. Using the notion of moving geometrically necessary dislocations (GNDs), suitable micromechanics interpretations are heuristically given for the higher order boundary conditions and the long distance particle interactions. Also, a comparison is made between this theory and the analogous virtual work principle (VWP)-based one, whereby their respective conceptual and methodological features are pointed out. The conditions under which the two theories lead to a same constitutive model are investigated, showing that, correspondingly, a certain indeterminacy exhibi…
Reciprocal vs nonreciprocal trade agreements: Which have been best to promote exports?
2019
The Doha Development Agenda recognizes the central role that international trade can play in the promotion of economic development. In fact, the increase of exports from developing countries to developed nations' markets has been considered a key element for developing countries to realize the potential benefits of globalization. Over the last decades, developed countries have provided preferential access to their markets to developing countries through nonreciprocal trade agreements. Moreover, developing countries have also participated in reciprocal trade agreements. This paper re-examines comparatively the effect of both kinds of trade agreements on exports from developing countries but …
The Chinese Bittersweet Cake in Orbea’s Internationalization
2017
Orbea is the oldest and biggest bicycle manufacturer in Spain and one of the most recognized bike brands in the world. With more than 175 years in the market, in the year 2007 Orbea decided to set up its third manufacturing plant in the Industrial park of Kunshan. After 8 years with activity there, in 2015 the company decided to close down the factory and reallocated its resources closer to the Headquarters. Some of the reasons that influenced its entry and exit decisions had their origin in the specific context of investment (place): China and the country-of-origin (COO) cluster in Kunshan. Other reasons of the reshoring and backshoring were related with the evolution of the sector, public…
AI for Resource Allocation and Resource Allocation for AI: a two-fold paradigm at the network edge
2022
5G-and-beyond and Internet of Things (IoT) technologies are pushing a shift from the classic cloud-centric view of the network to a new edge-centric vision. In such a perspective, the computation, communication and storage resources are moved closer to the user, to the benefit of network responsiveness/latency, and of an improved context-awareness, that is, the ability to tailor the network services to the live user's experience. However, these improvements do not come for free: edge networks are highly constrained, and do not match the resource abundance of their cloud counterparts. In such a perspective, the proper management of the few available resources is of crucial importance to impr…
Chronic exposure to ammonia induces isoform-selective alterations in the intracellular distribution and NMDA receptor-mediated translocation of prote…
2004
Hyperammonemia is responsible for most neurological alterations in patients with hepatic encephalopathy by mechanisms that remain unclear. Hyperammonemia alters phosphorylation of neuronal protein kinase C (PKC) substrates and impairs NMDA receptor-associated signal transduction. The aim of this work was to analyse the effects of hyperammonemia on the amount and intracellular distribution of PKC isoforms and on translocation of each isoform induced by NMDA receptor activation in cerebellar neurons. Chronic hyperammonemia alters differentially the intracellular distribution of PKC isoforms. The amount of all isoforms (except PKC zeta) was reduced (17-50%) in the particulate fraction. The con…
Objective Bayesian point and region estimation in location-scale models.
2007
Point and region estimation may both be described as specific decision problems. In point estimation, the action space is the set of possible values of the quantity on interest; in region estimation, the action space is the set of its possible credible regions. Foundations dictate that the solution to these decision problems must depend on both the utility function and the prior distribution. Estimators intended for general use should surely be invariant under one-to-one transformations, and this requires the use of an invariant loss function; moreover, an objective solution requires the use of a prior which does not introduce subjective elements. The combined use of an invariant informatio…
Development of a Low-Cost IoT System for Lightning Strike Detection and Location
2019
Lightning and thunder are some of the most violent natural phenomena. They generate a great deal of expenditure and economic loss, especially when they strike in cities. The identification of the concrete geographic area where they strike is of critical importance for emergency services in order to enhance their effectiveness by doing an intensive coverage of the affected area. To achieve this purpose at the city scale, this paper proposes the design, prototype, and validation of a distributed network of Internet of Things (IoT) devices. The IoT devices are empowered with lightning detection capabilities and are synchronized with the other devices in the sensor network. All of them cooperat…
Spatial mismatch through local public employment agencies Answers from a French quasi-experiment Spatial Mismatch through Local Public Employment Age…
2015
Using the unanticipated creation of a new agency in the French region of Lyon as a quasi-natural experiment, we question whether distance to local public employment agencies (LPEAs) is a new channel for spatial mismatch. Contrary to past evidence based on aggregated data and consistently with the spatial mismatch literature, we find no evidence of a worker/agency spatial mismatch, which pleads for a resizing of the French LPEA network. However, echoing with the literature on the institutional determinants of the local public employment agencies' efficiency, we do find detrimental institutional transitory effects.
Productivity analysis of Latvian companies using ORBIS database
2021
International audience; This research study uses ORBIS microdata at the company level to analyse productivity of 167 thousand economically active Latvian companies over 2011-2018. The aim of the study is twofold-to find factors consistently associated with productivity at the company level; and to recommend possible criteria for companies to receive a state support (from the view of enhancing aggregate productivity in the long term). Our research results show that productivity of Latvian companies is positively related to their size, age, as well as location closer to Riga and other big cities. However, there is a substantial within-group variation in productivity between companies. Multiva…
Cytogenetic characterization of HB2 epithelial cells from the human breast.
2014
HB2 is a cell line originated by subcloning of MTSV1-7 mammary luminal epithelial cells isolated from human milk and immortalization via introduction of the gene encoding simian virus 40 (SV40) large T antigen. Despite its wide utilization as non-neoplastic counterpart in assays aimed to elucidating various biochemical and genetical aspects of normal and tumoral breast cells, to our knowledge no literature data have so far appeared concerning the chromosomal characterization of the HB2 cells. Here, we report the cytogenetic characterization of the karyotype of HB2 cells, which puts in evidence the occurrence of changes in chromosomal number and structure and the presence of unidentified chr…