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showing 10 items of 1480 documents

Hypertonic fluid resuscitation from subarachnoid hemorrhage in rats: A comparison between small volume resuscitation and mannitol

2005

Abstract Objective Death and severe morbidity after subarachnoid hemorrhage (SAH) are mainly caused by global cerebral ischemia through increased intracranial pressure (ICP) and decreased cerebral blood flow (CBF). We have recently demonstrated neuroprotective effects of small volume resuscitation (7.5% saline in combination with 6% dextran 70) in an animal model of SAH, leading to normalization of increased ICP, reduced morphological damage and improved neurological recovery. In the present study, we compared the concept of small volume resuscitation represented by two clinically licenced hypertonic–hyperoncotic saline solutions with the routinely used hyperosmotic agent–mannitol–and inves…

MaleResuscitationTime FactorsSubarachnoid hemorrhageIntracranial PressureResuscitationmedicine.medical_treatmentHypertonic SolutionsFunctional LateralityRandom AllocationmedicineAnimalsMannitolcardiovascular diseasesRats WistarSalineIntracranial pressureNeurologic Examinationbusiness.industryDextransSubarachnoid Hemorrhagemedicine.diseaseRatsnervous system diseasesDextran 70Hypertonic salineDisease Models AnimalNeurologyCerebral blood flowCerebrovascular CirculationAnesthesiaTonicityNeurology (clinical)businessJournal of the Neurological Sciences
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Where are patients missed in the tuberculosis diagnostic cascade? A prospective cohort study in Ghana.

2020

BackgroundGhana's national prevalence survey showed higher than expected tuberculosis (TB) prevalence, indicating that many people with TB are not identified and treated. This study aimed to identify gaps in the TB diagnostic cascade prior to starting treatment.MethodsA prospective cohort study was conducted in urban and rural health facilities in south-east Ghana. Consecutive patients routinely identified as needing a TB test were followed up for two months to find out if sputum was submitted and/or treatment started. The causal effect of health facility location on submitting sputum was assessed before risk factors were investigated using logistic regression.ResultsA total of 428 persons …

MaleRural PopulationBacterial DiseasesRNA virusesResearch FacilitiesUrban PopulationPhysiologyHIV InfectionsPathology and Laboratory MedicineGhanaCohort StudiesGeographical Locations0302 clinical medicineImmunodeficiency VirusesHealth facilityHealth careOdds RatioMedicine and Health SciencesCoughingProspective Studies030212 general & internal medicineProspective cohort studyMultidisciplinaryRural healthQRMiddle AgedBody FluidsInfectious DiseasesMedical MicrobiologyResearch DesignViral PathogensVirusesTuberculosis Diagnosis and ManagementMedicineFemaleAnatomyPathogensmedicine.symptomResearch LaboratoriesResearch ArticleCohort studyAdultmedicine.medical_specialtyTuberculosisAdolescentScience030231 tropical medicineResearch and Analysis MethodsMicrobiologyYoung Adult03 medical and health sciencesSigns and SymptomsTuberculosis diagnosisDiagnostic MedicineRetrovirusesmedicineHumansTuberculosisMicrobial PathogensAgedbusiness.industryLentivirusSputumOrganismsBiology and Life SciencesHIVTropical Diseasesmedicine.diseaseMucusFamily medicinePeople and PlacesAfricaSputumHealth FacilitiesPhysiological ProcessesbusinessGovernment LaboratoriesPLoS ONE
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The cost of a school based mass treatment of schistosomiasis in Ugu District, KwaZulu Natal, South Africa in 2012.

2020

Introduction The Neglected Tropical Diseases Roadmap of the WHO set targets for potential elimination as a "public health problem" for the period 2012-2020 in multiple countries in Africa, with the aim of global elimination of schistosomiasis as a "public health problem" by 2025. Aim The purpose of the study was to estimate the cost from a provider's perspective of the Department of Health's Schistosomiasis Mass Drug Administration (MDA) in Ugu District, KwaZulu-Natal in 2012, with a view to project the costs for the entire KwaZulu Natal Province. Methods A total of 491 public schools and 16 independent schools in Ugu District, a predominantly rural district in KwaZulu-Natal with a total of…

MaleRural PopulationBudgetsEndemic DiseasesFinancial ManagementTotal costEconomicsSocial SciencesPraziquantelGeographical locationsSouth AfricaFamilies0302 clinical medicineLearning and MemorySociologyMedicine and Health SciencesSchistosomiasisPsychology030212 general & internal medicineSocioeconomicsActivity-based costingChildChildrenAnthelminticsMultidisciplinarySchoolsPharmaceuticsQRHelminth InfectionsNeglected tropical diseasesMedicineMass Drug AdministrationFemaleResearch ArticleNeglected Tropical Diseasesmedicine.medical_specialtyDrug AdministrationAdolescentScience030231 tropical medicineDrug CostsSampling StudiesDirect Service CostsEducation03 medical and health sciencesHuman LearningDrug TherapymedicineParasitic DiseasesCapital costHumansLearningHuman resourcesUnit costCost databaseRetrospective StudiesSchool Health Servicesbusiness.industryPublic healthCognitive PsychologyBiology and Life SciencesTropical DiseasesAge GroupsCapital ExpendituresPeople and PlacesAfricaCognitive SciencePamphletsPopulation GroupingsbusinessVDP::Samfunnsvitenskap: 200::Urbanisme og fysisk planlegging: 230FinanceNeurosciencePloS one
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The financial burden of non-communicable chronic diseases in rural Nigeria: Wealth and gender heterogeneity in health care utilization and health exp…

2016

Objectives Better insights into health care utilization and out-of-pocket expenditures for non-communicable chronic diseases (NCCD) are needed to develop accessible health care and limit the increasing financial burden of NCCDs in Sub-Saharan Africa. Methods A household survey was conducted in rural Kwara State, Nigeria, among 5,761 individuals. Data were obtained using biomedical and socio-economic questionnaires. Health care utilization, NCCD-related health expenditures and distances to health care providers were compared by sex and by wealth quintile, and a Heckman regression model was used to estimate health expenditures taking selection bias in health care utilization into account. Res…

MaleRural PopulationEconomicsHealth Care ProvidersHBSocial Scienceslcsh:MedicineTransportationHealth Services AccessibilityGeographical LocationsHousehold survey0302 clinical medicineCost of IllnessRA0421Surveys and QuestionnairesHealth carePrevalenceMedicine and Health SciencesMedicinePublic and Occupational Health030212 general & internal medicine10. No inequalityChildlcsh:Sciencemedia_commonFamily CharacteristicsMultidisciplinary030503 health policy & services1. No povertyMiddle AgedSocioeconomic Aspects of Health3. Good healthPeer reviewChild PreschoolSDG 1 - No PovertyEngineering and Technology/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemale0305 other medical science/dk/atira/pure/sustainabledevelopmentgoals/no_povertyResearch ArticleAdultFinancing PersonalAdolescentmedia_common.quotation_subjectQuality careNigeria03 medical and health sciencesYoung AdultHealth EconomicsSDG 3 - Good Health and Well-beingHumansAgedSelection biasFinanceConsumption (economics)Health economicsbusiness.industrylcsh:RInfant NewbornInfantTargeted interventionsPatient Acceptance of Health CareHealth CareCross-Sectional StudiesHealth Care FacilitiesChronic DiseasePeople and PlacesAfricalcsh:QHealth ExpendituresbusinessFinanceHealth Insurance
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Overweight, obesity, and thinness among a nationally representative sample of Norwegian adolescents and changes from childhood: Associations with sex…

2021

Objective To estimate the prevalence of overweight, obesity, and thinness among Norwegian 13-year-olds and the changes from childhood (age 8 years) to adolescence (age 13 years); and to explore associations with sex, region, and population density from childhood to adolescence. Design We used longitudinal, anthropometric data collected by school health nurses conducted in Norway. Weight status was classified according to the International Obesity Task Force cut-offs for overweight, obesity, and thinness, and according to mean body mass index (kg/m2). Participants The Norwegian Youth Growth Study, consisting of a nationally representative sample of Norwegian 13-year-olds (n = 1852; 50.7% gi…

MaleRural PopulationPediatric Obesity030309 nutrition & dieteticsPhysiologyOverweightAdolescentsBody Mass IndexGeographical LocationsFamilies0302 clinical medicineOdds RatioPrevalence030212 general & internal medicineLongitudinal StudiesChildChildren0303 health sciencesMultidisciplinarySchoolsNorwayQRAge FactorsEuropePhysiological ParametersVDP::Medisinske Fag: 700::Helsefag: 800CohortlanguageMedicineFemalemedicine.symptomResearch ArticleChildhood ObesityAdolescentScienceNorwegianChildhood obesity03 medical and health sciencesSex FactorsPopulation MetricsThinnessmedicineHumansObesityPopulation DensityPopulation Biologybusiness.industryBody WeightBiology and Life SciencesOdds ratioOverweightmedicine.diseaseObesityConfidence intervallanguage.human_languageCross-Sectional StudiesAge GroupsPeople and PlacesPopulation GroupingsbusinessBody mass indexDemography
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Current status of Schistosoma mansoni infection among previously treated rural communities in the Abbey and Didessa Valleys, Western Ethiopia: Implic…

2021

Background Schistosoma constitutes a major public health problem and developmental challenges in the majority of developing and subtropical regions. The World Health Organization has set guidelines for the control and elimination of schistosomiasis. Ethiopia is providing school-based Mass Drug Administration (MDA) at the study areas of the Abbey and Didessa Valleys of western Ethiopian since 2015. Moreover, mass treatment was already done in the same villages 30 years ago. However, the current Schistosoma mansoni infection status among humans and snails in the study areas is not known. Hence, the present study aims to determine the current status. Methods A community-based cross-sectional …

MaleRural PopulationTopographySchistosoma MansoniSanitationSnailsMarine and Aquatic SciencesGeographical LocationsFeces0302 clinical medicineMedical ConditionsHygienePrevalenceMedicine and Health SciencesSchistosomiasisPublic and Occupational Health030212 general & internal medicineSanitationSocioeconomicsChildEggs per grammedia_commonMultidisciplinarySchoolsbiologyQREukaryotaHygieneGeographyHelminth InfectionsChild PreschoolMass Drug AdministrationSchistosomaMedicineFemaleSchistosoma mansoniEnvironmental HealthResearch ArticleNeglected Tropical DiseasesFreshwater EnvironmentsValleysWet seasonAdultmedicine.medical_specialtyAdolescentmedia_common.quotation_subjectScience030231 tropical medicineEnvironment03 medical and health sciencesYoung AdultRiversSurface WaterHelminthsparasitic diseasesmedicineParasitic DiseasesAnimalsHumansMass drug administrationSchistosomaLandformsPublic healthEcology and Environmental SciencesOrganismsBiology and Life SciencesAquatic EnvironmentsGeomorphologyBodies of Waterbiology.organism_classificationTropical DiseasesInvertebratesSchistosomiasis mansoniVDP::Medical disciplines: 700Health CareCross-Sectional StudiesPeople and PlacesAfricaEarth SciencesEthiopiaHydrologyZoologyPLoS ONE
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Older adults’ activity destinations before and during COVID-19 restrictions: From a variety of activities to mostly physical exercise close to home

2021

The aim was to study various types of older adult's activity destinations (counts, frequency of visitation, and distance from home) in the pre-COVID-19 era, and to study prospectively how COVID-19-related regulations limiting mobility affected these. Using a map-based questionnaire, 75-85-year-old participants reported activity destinations, that is, any destinations for physical exercise, destinations facilitating one's outdoor mobility, and destinations for other activities, which they had visited several times during the past month. At baseline, a variety of activity destinations was reported, but during COVID-19, destinations reported markedly declined in number, they were reported pred…

MaleSelf-assessmentulkoiluSelf-AssessmentaktiivisuusHealth (social science)Coronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Geography Planning and DevelopmentPhysical exerciseWalkingDestinationsliikuntapandemiat03 medical and health sciencesmobility limitation0302 clinical medicineurheiluetäisyysSurveys and QuestionnairesHumansparticipationCognitive Dysfunction030212 general & internal medicineExercise physiologyExerciseRecreationAgedosallistuminenAged 80 and overSpatial Analysis030505 public healthagingkotiPublic Health Environmental and Occupational HealthCorona-virusCOVID-19LimitingGeographyactivity locationikääntyminenFemalerajoitukset0305 other medical scienceactivity-spaceikääntyneetfyysinen aktiivisuusDemographyHealth & Place
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Implicit learning of a repeated segment in continuous tracking: A reappraisal

2006

Several prior studies (e.g., Shea, Wulf, Whitacre, & Park, 2001; Wulf & Schmidt, 1997) have apparently demonstrated implicit learning of a repeated segment in continuous-tracking tasks. In two conceptual replications of these studies, we failed to reproduce the original findings. However, these findings were reproduced in a third experiment, in which we used the same repeated segment as that used in the Wulf et al. studies. Analyses of the velocity and the acceleration of the target suggests that this repeated segment could be easier to track than the random segments serving as control, accounting for the results of Wulf and collaborators. Overall these experiments suggest that lea…

MaleSerial reaction timeTime Factors[ INFO.INFO-TS ] Computer Science [cs]/Signal and Image ProcessingPhysiologySpeech recognition[SHS.PSY]Humanities and Social Sciences/Psychology050109 social psychologyExperimental and Cognitive Psychology[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processingTracking (particle physics)050105 experimental psychologyRandom Allocation[ SHS.PSY ] Humanities and Social Sciences/PsychologyAcceleration[INFO.INFO-TS]Computer Science [cs]/Signal and Image ProcessingPhysiology (medical)Reaction TimeHumansLearningTraitement du signal et de l'imagePsychology0501 psychology and cognitive sciencesStudentsGeneral PsychologyAnalysis of VarianceCommunicationbusiness.industry05 social sciencesSignal and Image processingRetention PsychologyRecognition PsychologyGeneral MedicineImplicit learningNeuropsychology and Physiological PsychologyPsychologieFemalebusinessPsychology[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processingPsychomotor PerformanceTraitement du signal et de l'image (Informatique)
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Two‐dimensional analysis of myocardial protein expression following myocardial ischemia and reperfusion in rabbits

2002

Myocardial ischemia and reperfusion injury (MI/R) can be related to leukocyte activation with subsequent release of cytokines and oxygen derived free radicals. Activation of the complement system has been implicated in the pathogenesis of myocardial ischemia and reperfusion injury. Inflammatory injury will subsequently result in cellular activation and protein synthesis. In the present study we analyzed the myocardial protein expression and its pattern following myocardial ischemia and reperfusion, with and without complement inhibition with the synthetic serine protease inhibitor Futhan/nafamstat mesilate (FUT-175) known to inhibit classical and alternative complement pathway in a rabbit m…

MaleSerine Proteinase InhibitorsNecrosisProteomeNeutrophilsMyocardial IschemiaIschemiaMyocardial Reperfusion InjuryPharmacologyGuanidinesBiochemistrySuperoxide dismutaseNecrosisRandom AllocationComplement inhibitormedicineAnimalsElectrophoresis Gel Two-DimensionalCreatine KinaseMolecular BiologybiologySuperoxide DismutaseChemistryGene Expression ProfilingMyocardiumHemodynamicsProteinsalpha-Crystallin B Chainmedicine.diseaseBenzamidinesComplement systemBiochemistrybiology.proteinAlternative complement pathwayCreatine kinaseRabbitsmedicine.symptomReperfusion injuryPROTEOMICS
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Sex change in plants and animals: a unified perspective

2014

The capacity of organisms to change their sex has evolved independently in several plant and animal lineages. Sex change has been widely studied, but research approaches have differed for plants and animals, and conclusions have often been taxon-specific. Although sex allocation theory provides a unifying framework for the study of sex change, this unity has not always been appreciated, especially in the botanical literature. Here, we review sex change with regard to its representation in relation to taxonomy and other sexual systems, with regard to its suggested adaptive benefits, and to the role of taxon-specific body architecture, such as modularity and gonadal structure. We highlight di…

MaleSex DifferentiationGonadal structureEcologyReproductionfungiFlowersSex Determination ProcessesBiologyBiological EvolutionSex changeEvolutionary biologyAnimalsFemaleHermaphroditic Organismssense organsskin and connective tissue diseasesEcology Evolution Behavior and SystematicsSex allocationJournal of Evolutionary Biology
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