Search results for "loop"
showing 10 items of 608 documents
High levels of HIF-2α highlight an immature neural crest-like neuroblastoma cell cohort located in a perivascular niche
2007
High HIF-2alpha protein levels in the sympathetic nervous system-derived childhood tumour neuroblastoma as well as immature phenotype correlate to unfavourable outcome. Here we show that a small subset of perivascularly located, strongly HIF-2alpha-positive tumour cells (MYCN amplified) lacks expression of differentiation markers, but expresses neural crest and early sympathetic progenitor marker genes such as Notch-1, HES-1, c-Kit, dHAND, and vimentin. HIF-2alpha- and CD68-positive tumour-associated macrophages were frequently found close to the immature and HIF-2alpha-positive neuroblastoma cells and as VEGF levels are high in the perivascular niche, we hypothesize that neuroblastoma neur…
Systematic classification of two-loop realizations of the Weinberg operator
2015
We systematically analyze the $d=5$ Weinberg operator at 2-loop order. Using a diagrammatic approach, we identify two different interesting categories of neutrino mass models: (i) Genuine 2-loop models for which both, tree-level and 1-loop contributions, are guaranteed to be absent. And (ii) finite 2-loop diagrams, which correspond to the 1-loop generation of some particular vertex appearing in a given 1-loop neutrino mass model, thus being effectively 2-loop. From the large list of all possible 2-loop diagrams, the vast majority are infinite corrections to lower order neutrino mass models and only a moderately small number of diagrams fall into these two interesting classes. Moreover, all …
Validation of Loop-Mediated Isothermal Amplification (LAMP) Field Tool for Rapid and Sensitive Diagnosis of Contagious Agalactia in Small Ruminants
2020
Simple Summary Contagious agalactia (CA) is an infectious disease of small ruminants endemic in the Mediterranean countries, causing significant socioeconomic impacts predominantly on small-scale farmers who still subsist on marginal lands. Mycoplasma agalactiae is historically considered the principal etiological agent of CA, especially in sheep. Clinical signs are characterised by mastitis, arthritis, keratoconjunctivitis and occasionally, abortion. Rapid, accurate and cost-effective field tests are urgently needed for effective control of M. agalactiae mastitis. Our study illustrated the validation of a Loop-Mediated Isothermal Amplification (LAMP) test for the detection of M. agalactiae…
NO formation tendency characterization for solid fuels in fluidized beds
2013
Abstract Usually the standard fuel analysis is not enough to allow for accurate NO emission predictions in large scale fluidized bed combustion. This paper presents NO formation tendency characterization results from novel laboratory measurements in a small-scale fluidized bed combustor. With the special two-stage oxidation method it is possible to eliminate the observed problems of unstable test conditions during rapid pyrolysis of high-volatile fuels in batch combustion. Experimental results of the conversion of fuel nitrogen to NO are presented for wide range of fuels, ranging from coal-type fuels to peat, biomasses and wastes. A NO formation tendency database is formed based on the resu…
Structure of longitudinal chromomagnetic fields in high energy collisions
2014
We compute expectation values of spatial Wilson loops in the forward light cone of high-energy collisions. We consider ensembles of gauge field configurations generated from a classical Gaussian effective action as well as solutions of high-energy renormalization group evolution with fixed and running coupling. The initial fields correspond to a color field condensate exhibiting domain-like structure over distance scales of order the saturation scale. At later times universal scaling emerges at large distances for all ensembles, with a nontrivial critical exponent. Finally, we compare the results for the Wilson loop to the two-point correlator of magnetic fields.
Modeling an X-ray Flare on Proxima Centauri: evidence of two flaring loop components and of two heating mechanisms at work
2003
We model in detail a flare observed on Proxima Centauri with the EPIC-PN on board XMM-Newton at high statistics and high time resolution and coverage. Time-dependent hydrodynamic loop modeling is used to describe the rise and peak of the light curve, and a large fraction of the decay, including its change of slope and a secondary maximum, over a duration of more than 2 hours. The light curve, the emission measure and the temperature derived from the data allow us to constrain the loop morphology and the heating function and to show that this flare can be described with two components: a major one triggered by an intense heat pulse injected in a single flaring loop with half-length ~1.0 10^{…
Contribution of mode coupling and phase-mixing of Alfv\'en waves to coronal heating
2017
This research has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (grant agreement No. 647214) and from the UK Science and Technology Facilities Council. This work used the DiRAC Data Centric system at Durham University, operated by the Institute for Computational Cosmology on behalf of the STFC DiRAC HPC Facility (www.dirac.ac.uk. This equipment was funded by a BIS National E-infrastructure capital grant ST/K00042X/1, STFC capital grant ST/K00087X/1, DiRAC Operations grant ST/K003267/1 and Durham University. Context. Phase-mixing of Alfvén waves in the solar corona has been identified as one possible candid…
Experiments and predictions of the transition of the flow pattern with impeller clearance in stirred tanks
2001
In the present work, the double- to single-loop flow pattern transition in a stirred vessel equipped with a Rushton turbine is investigated by Laser Doppler anemometry (LDA). In particular, the clearance at which such transition occurs is assessed by comparing axial velocity profiles underneath the impeller. Computational fluid dynamics (CFD) simulations of the same system are carried out, by employing the 'inner-outer' fully predictive computation strategy. The comparison of predicted results with the experimental data collected shows that the transition is well reproduced by simulations. A good agreement on the mean velocities is also observed but for the impeller discharge stream angle t…
Effect of different aqueous solutions of pure salts and salt mixtures in reverse electrodialysis systems for closed-loop applications
2018
Abstract Reverse Electrodialysis (RED) in a closed-loop arrangement is a viable way to convert low-grade heat into electric power. The present work experimentally investigates the use of pure salt- and equimolar two salts-water solutions as feeds in a lab-scale RED unit. RED performances were analysed in terms of Open Circuit Voltage (OCV), stack resistance and corrected power density. The pure salts and the mixtures employed were chosen via a computational analysis. Effect of feed solution velocity and concentration was investigated. Results concerning the pure salt-water experiments show that NH4Cl is the most performing salt in the concentration range probed, while higher power density v…
Integrable Systems and Factorization Problems
2002
The present lectures were prepared for the Faro International Summer School on Factorization and Integrable Systems in September 2000. They were intended for participants with the background in Analysis and Operator Theory but without special knowledge of Geometry and Lie Groups. In order to make the main ideas reasonably clear, I tried to use only matrix algebras such as $\frak{gl}(n)$ and its natural subalgebras; Lie groups used are either GL(n) and its subgroups, or loop groups consisting of matrix-valued functions on the circle (possibly admitting an extension to parts of the Riemann sphere). I hope this makes the environment sufficiently easy to live in for an analyst. The main goal is…