Search results for "m.m.f."
showing 10 items of 60 documents
Application of entropic approach to estimate the mean flow velocity and Manning roughness coefficient in a high-curvature flume
2016
The entropy-based approach allows the estimation of the mean flow velocity in open channel flow by using the maximum flow velocity. The linear relationship between the mean velocity, umax, and the mean flow velocity, um, through the dimensionless parameter Φ(M), has been verified both in natural rivers and in laboratory channels. Recently, the authors of this study investigated the reliability of the entropy-based formula in a straight channel and under different bed and side-walls' roughness conditions. The present study aims to further validate the entropy-based approach and to explore the effectiveness of entropy-based formula in high curvature channels. Results show that as the effect o…
Antibacterial and Antifungal Activities of Acetonic Extract from Paullinia cupana Mart Seeds
2013
The antibacterial and antifungal activities of the acetone extract from Paullinia cupana var. sorbilis Mart. (Sapindaceae) seeds, commonly called guarana, were assessed against selected bacterial and fungal strains. We tested the extract against both standard American Type Culture Collection (ATCC) and clinically isolated (CI) bacterial strains and three fungal strains. Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values for bacteria and MIC and minimum fungicidal concentration for fungi were determined. The extract showed an activity against the nine bacterial strains tested, both CI and ATCC strains (MIC comprised between 32 and 128 μm/mL and MBC bet…
In vitro antifungal properties of mouthrinses containing antimicrobial agents
1997
The purpose of this study was to investigate the in vitro antifungal properties of seven commercial mouthrinses containing antimicrobial agents. These included cetylpyridinium chloride (CPC), chlorhexidine digluconate (CHX), hexetidine (HEX), sanguinarine (SNG), and triclosan (TRN). The minimum fungicidal concentration (MFC) against six species of yeasts was determined by a broth macrodilution method. The kill-time of mouthrinses at half the concentration of the commercial formulations was also determined. MFCs were achieved with each mouthrinse, except the SNG-containing mouthrinse, against all the organisms being tested. However, the CPC-containing mouthrinse appeared more active than the…
Mapping the network of pathways of CO diffusion in myoglobin.
2010
The pathways of diffusion of a CO molecule inside a myoglobin protein and toward the solvent are investigated. Specifically, the three-dimensional potential of mean force (PMF or free energy) of the CO molecule position inside the protein is calculated by using the single-sweep method in concert with fully resolved atomistic simulations in explicit solvent. The results are interpreted under the assumption that the diffusion of the ligand can be modeled as a navigation on the PMF in which the ligand hops between the PMF local minima following the minimum free energy paths (MFEPs) with rates set by the free energy barriers that need to be crossed. Here, all the local minima of the PMF, the MF…
Conversion of levulinic acid to γ-valerolactone over Zr-containing metal-organic frameworks: Evidencing the role of Lewis and Brønsted acid sites
2021
Zr-containing UiO-66 and MOF-808 are evaluated for converting levulinic acid (LA) into γ-valerolactone (GVL) through various routes: (i) Step-wise esterification of LA to n-butyl levulinate (nBuL) and Meerwein-Ponndorf-Verley (MPV) reduction to GVL; (ii) One-pot two-steps esterification with n-butanol followed by MPV reduction with sec-butanol; and (iii) direct conversion of LA into GVL through a tandem reaction. Selection of this multistep complex reaction evidences the participation of the different acid sites (Lewis or Brønsted) of the material in each individual step: Brønsted-induced acid sites catalyze esterification reaction efficiently, while Lewis acid sites are the preferred sites…
Metal NHC Complexes with Naphthalimide Ligands as DNA-Interacting Antiproliferative Agents
2017
Naphthalimide-based N-heterocyclic carbene (NHC) complexes of the type [(1,5-cyclooctadiene)(NHC)RhCl)] (4 a-c), [(p-cymene)(NHC)RuCl2 )] (5 a-c), and [(NHC)CuBr] (6 a-c) were synthesized and investigated as antiproliferative agents that target DNA. The cytotoxic effects were largely driven by the naphthalimide structure, which is a DNA-intercalating moiety. Regarding the metal center, the highest activities were observed with the rhodium complexes, and cytotoxic activity was significantly lower for the ruthenium derivatives. The stable coordination of the NHC ligands of selected complexes 4 b and 5 b in solution was confirmed, and their DNA binding properties were studied by UV/Vis spectro…
MIS 5.5 highstand and future sea level flooding at 2100 and 2300 in tectonically stable areas of central mediterranean sea: Sardinia and the pontina …
2021
Areas of the Mediterranean Sea are dynamic habitats in which human activities have been conducted for centuries and which feature micro-tidal environments with about 0.40 m of range. For this reason, human settlements are still concentrated along a narrow coastline strip, where any change in the sea level and coastal dynamics may impact anthropic activities. We analyzed light detection and ranging (LiDAR) and Copernicus Earth observation data. The aim of this research is to provide estimates and detailed maps (in three coastal plain of Sardinia (Italy) and in the Pontina Plain (southern Latium, Italy) of: (i) the past marine transgression occurred during MIS 5.5 highstand 119 kyrss BP
Aplicación del binomio Apodemus sylvaticus /helminto como bioindicador de la regeneración del Parc Natural de la Serra Calderona (Comunitat Valencian…
2015
El estudio del binomio Apodemus sylvaticus/helminto ha sido propuesto como un bioindicador del proceso de regeneración postincendio en ecosistemas mediterráneos. El presente trabajo, enmarcado en un proyecto multidisciplinar que lleva por título “Procesos de Recuperación de Ecosistemas Perturbados por el Fuego a través del modelo Helmintos/Micromamíferos” y que fue iniciado por el grupo Parasites & Fire, del Departamento de Parasitología de la Universidad de Farmacia de la Universidad de Valencia, ofrece nuevos resultados que avalan su validación en el Parc Natural de la Serra Calderona (Comunitat Valenciana, España), la cual sufrió un devastador incendio forestal en 1992. Durante 21 años (…
The Late Miocene and Early Pliocene micromammal faunas from the Alcoy and Cabriel basins
2015
Objetivos El objetivo principal de este trabajo ha sido el muestreo y estudio de los niveles fosilíferos encontrados en el Barranco del Gormaget, en la Cuenca de Alcoy. Una vez estuvo clara la taxonomía de los abundantes restos de micromamíferos procedentes de estos yacimientos, intentamos alcanzar objetivos más específicos, tales como: - Datación relativa de las distintas localidades en virtud de su contenido faunístico. - Propuesta de una biozonación local para los yacimientos del Barranco del Gormaget. - Interpretación de la paleoecología de los yacimientos estudiados, basada en las proporciones relativas de los taxones encontrados en cada uno de ellos. Además, en esta tesis se presentan…
Los mamíferos del Mioceno Inferior de la Cuenca de Ribesalbes-Alcora (Castelló, España)
2017
Objetivos El propósito principal de esta tesis es el estudio taxonómico, paleoecológico y bioestratigráfico de los mamíferos fósiles del Neógeno continental de Araia d’Alcora, en la Cuenca de Ribesalbes-Alcora (Castelló, España), a partir de la prospección de diversas secciones y del muestreo de los yacimientos de mayor interés. Los principales objetivos planteados en esta tesis han sido: • La obtención de un registro lo más completo posible de las faunas de mamíferos del área de estudio, mediante la identificación de niveles fosilíferos y la toma de muestras suficientemente grandes para obtener colecciones de fósiles representativas. • Determinación taxonómica de los grupos de mamíferos ha…