Search results for "magic"
showing 10 items of 160 documents
Delivery and therapeutic potential of human granzyme B
2010
Summary: Granzyme B (GzmB) is used by cytotoxic lymphocytes as a molecular weapon for the defense against virus-infected and malignantly transformed host cells. It belongs to a family of small serine proteases that are stored in secretory vesicles of killer cells. After secretion of these cytolytic granules during killer cell attack, GzmB is translocated into the cytosol of target cells with the help of the pore-forming protein perforin. GzmB has adopted similar protease specificity as caspase-8, and once delivered, it activates major executioner apoptosis pathways. Since GzmB is very effective in killing human tumor cell lines that are otherwise resistant against many cytotoxic drugs and …
Palladium Supported on Cross-Linked Imidazolium Network on Silica as Highly Sustainable Catalysts for the Suzuki Reaction under Flow Conditions
2013
Highly cross-linked imidazolium-based materials, obtained by radical oligomerization of bis-vinylimidazolium salts in the presence of 3-mercaptopropyl-modified silica gel, were used as supports for palladium catalysts. Thanks to the high imidazolium loading these materials were able to support a high amount of the metal (10 wt%). Such materials were characterized by several techniques (13C magic angle spinning nuclear magnetic resonance, the Brunauer-Emmett-Teller technique, X-ray photoelectron spectroscopy, and transmission electron microscopy). The palladium catalysts displayed good activity allowing the synthesis of several biphenyl compounds in high yields working with only 0.1 mol% of …
Amantadine for chronic hepatitis C: a magic bullet or yet another dead duck?
2001
Towards Hybrid Aesthetics
1998
In order to avoid limiting hybridity to sterile ‘racial’ considerations, it needs to be placed firmly in its cultural context. Cultures and civilisations have often been taken as synonyms. For E.B. Tylor in Primitive Culture, words such as ‘culture’ or ‘civilization’ refer to the body of sciences, arts, beliefs, moral principles, laws, customs, in short all the habits and faculties acquired by human beings as part of their social life. Tylor draws a distinction between three stages in the evolution of societies: the savage, the barbarian and the civilised. He thus reintroduces a hierarchy between ‘civilisation’, which is reserved for the highest point on his evolutionary scale, and ‘culture…
La caiguda de Felicià Piquer, bruixot processat per la Inquisició de València (1669-1673)
2019
Resum: Felicià Piquer és un modest bruixot de la ciutat de València, amb no merescuda fama de sacatesoros; com tots aquests, té algun coneixement de màgia i sobretot molta xerrameca i poca vergonya, tot i que la seua característica personal és que empra les seues operacions màgiques per a abusar sexualment de dones, cosa que acabarà portant-lo a la presó reial i finalment als calabossos del sant Ofici; al seu procés inquisitorial, entre els anys 1669 i 1673 es descriuen les seues darreres aventures, habilitats, tècniques i instruments i modus operandi, així com la seua trista fi, delatat fins i tot pels seus companys de presó.
 
 Paraules clau: Inquisició, bruixeria, processos in…
Màgia i fantasia al servei de les nobles nissagues: el cas de Nofra-dona Dolcina en la novel·la històrica de Vicent Josep Escartí
2019
Resum: Dos dels elements més identificables en la novel·la històrica de Vicent Josep Escartí són, per una banda, el component màgic i fantàstic i, per una altra, l’existència de dues nobles nissagues: els Roger i els Arcàngel de Sant Esteve. De fet, la primera ja s’apuntà subtilment en «El fill de Gepa» i es desenvolupà en «Epistolari del Comte de l’Hortxà», primer i segon relat de Barroca mort (1988). Posteriorment, s’estengué a Dies d’ira (1992) ?Days of Wrath (2013)?, Els cabells d’Absalom (1996), Nomdedéu (2002), Naumàquia (2004) i El mas de les ànimes (2019). Amb Espècies perdudes (1997) sorgí el segon llinatge, que continuà en L’abellerol mort (2009), en les quals els Roger també s’en…
Magnetic Resonance Microscopy Contribution to Interpret High-Resolution Magic Angle Spinning Metabolomic Data of Human Tumor Tissue
2010
[EN] HRMAS NMR is considered a valuable technique to obtain detailed metabolic profile of unprocessed tissues. To properly interpret the HRMAS metabolomic results, detailed information of the actual state of the sample inside the rotor is needed. MRM (Magnetic Resonance Microscopy) was applied for obtaining structural and spatially localized metabolic information of the samples inside the HRMAS rotors. The tissue was observed stuck to the rotor wall under the effect of HRMAS spinning. MRM spectroscopy showed a transference of metabolites from the tissue to the medium. The sample shape and the metabolite transfer after HRMAS indicated that tissue had undergone alterations and it can not be s…
Determination of metabolite concentrations in human brain tumour biopsy samples using HR-MAS and ERETIC measurements.
2009
Accurate determination of the concentration of the metabolites contained in intact human biopsies of 10 glioblastoma multiforme samples was achieved using one-dimensional 1H high-resolution magic angle spinning (HR-MAS) NMR combined with ERETIC™ (electronic reference to in vivo concentrations) measurements. The amount of sample used ranged from 6.8 to 12.9 mg. Metabolite concentrations were measured in each sample using two methods: with DSS (2,2-dimethyl-2-silapentane-5-sulfonate sodium salt) as an internal reference and with ERETIC™ as an external electronically generated reference. The ERETIC™ signal was shown to be highly reproducible and did not affect the spectral quality. The concent…
Dowsing from the Late Middle Ages to the Twentieth Century: The Practices, Uses and Interpretations of an Element of European Magic
2012
Dowsing was an element of European folk magic. With the help of simple wooden rods persons with special magical abilities were supposed to be able to find hidden objects, from buried treasures to subterranean springs. The rise of dowsing can be traced to its use in the emerging mining centres of Central Europe around 1500. However, dowsers soon claimed nearly universal magical knowledge. Even though dowsing encountered strong scepticism, a number of early modern scholars and scientists tried to explain the alleged efficacy of the rod in a number of different ways, ranging from demonological arguments to the atom theory, and the idea of an all-encompassing world spirit. From the eighteenth …
Los géneros literarios y la etnografía del habla
2019
Este artículo se ocupa de los géneros literarios desde un punto de vista etnolingüístico. Los acercamientos habituales a este problema consideran los géneros literarios como modalidades de la literatura en las que se evidencian determinadas actitudes de los participantes: así, la poesía destacaría la contribución del hablante, el drama la del oyente y la narrativa aspiraría a reflejar el mundo exterior. Está muy extendida la idea de que estas tres modalidades son características de la cultura occidental, en tanto que las culturas más "primitivas" sólo conocerían la poesía, o incluso el drama (es lo que sucede en China y en el Japón), pero nunca la narrativa, el género más complejo y tardío.…