Search results for "maintenance"

showing 10 items of 392 documents

Manipulating mtDNA in vivo reprograms metabolism via novel response mechanisms.

2019

Mitochondria have been increasingly recognized as a central regulatory nexus for multiple metabolic pathways, in addition to ATP production via oxidative phosphorylation (OXPHOS). Here we show that inducing mitochondrial DNA (mtDNA) stress in Drosophila using a mitochondrially-targeted Type I restriction endonuclease (mtEcoBI) results in unexpected metabolic reprogramming in adult flies, distinct from effects on OXPHOS. Carbohydrate utilization was repressed, with catabolism shifted towards lipid oxidation, accompanied by elevated serine synthesis. Cleavage and translocation, the two modes of mtEcoBI action, repressed carbohydrate rmetabolism via two different mechanisms. DNA cleavage activ…

DYNAMICSLife CyclesSTRESSMITOCHONDRIAL-DNAADN mitocondrialQH426-470BiochemistryOxidative PhosphorylationLarvaeAdenosine TriphosphateTRANSCRIPTIONPost-Translational ModificationEnergy-Producing OrganellesProtein MetabolismOrganic CompoundsDrosophila MelanogasterChemical ReactionsMETHYLATIONEukaryotaAcetylationAnimal ModelsDNA Restriction EnzymesKetonesCellular ReprogrammingMitochondrial DNAMitochondriaTRANSLOCATIONNucleic acidsInsectsChemistryDROSOPHILAExperimental Organism SystemsPhysical SciencesSURVIVALCarbohydrate MetabolismCellular Structures and OrganellesMetabolic Networks and PathwaysResearch ArticlePyruvateArthropodaForms of DNAeducationCarbohydratesBioenergeticsResearch and Analysis MethodsDNA MitochondrialBiokemia solu- ja molekyylibiologia - Biochemistry cell and molecular biologyModel OrganismsGenetiikka kehitysbiologia fysiologia - Genetics developmental biology physiologyGeneticsAnimalsHumansBiology and life sciencesOrganic ChemistryOrganismsChemical CompoundsProteinsDNACell BiologyInvertebratesDELETIONSOxidative StressMetabolismMAINTENANCEDiabetes Mellitus Type 2Animal Studies1182 Biochemistry cell and molecular biologyAcidsDevelopmental BiologyPLoS Genetics
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Condition Monitoring Technologies for Synthetic Fiber Ropes - a Review

2020

This paper presents a review of different condition monitoring technologies for fiber ropes. Specifically, it presents an overview of the articles and patents on the subject, ranging from the early 70’s up until today with the state of the art. Experimental results are also included and discussed in a conditionmonitoring context,where failuremechanisms and changes in physical parameters give improved insight into the degradation process of fiber ropes. From this review, it is found that automatic width measurement has received surprisingly little attention, and might be a future direction for the development of a continuous condition monitoring system for synthetic fiber ropes.

Damage detectionComputer scienceEnergy Engineering and Power TechnologyContext (language use)computer visiondamage detectionSystems engineeringcondition based maintenance (cbm)TA168health monitoringComputer Science (miscellaneous)Degradation processSafety Risk Reliability and QualityCivil and Structural Engineeringvibration analysisx-ray tomographyFiber (mathematics)ultrasoundMechanical EngineeringCondition monitoringelectromagnetic methodTA213-215thermographyEngineering machinery tools and implementsSynthetic fiberSystems engineeringoptical damage sensorsInternational Journal of Prognostics and Health Management
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An empirical study of lean production in ceramic tile industries in Spain

2006

PurposeTo determine the degree of use of some of the most representative lean production (LP) practices in the Spanish ceramic tile industry, their relationship with plant size and their effect on the operational performance of the companies in the sector.Design/methodology/approachA questionnaire was developed for data collection. Findings are presented from 76 companies (79.17 per cent of the total sample) that specialise in single firing ceramics.FindingsIn the sector under study, there is one set of practices that have as yet scarcely been implemented (group technology, kanban, reduction of set‐up time, development of multi‐function employees and visual factory) and another set whose us…

Data collectionPsicologia socialStrategy and Managementmedia_common.quotation_subjectGeneral Decision SciencesKanbanSample (statistics)Total productive maintenanceLean manufacturingManufacturing engineeringEmpirical researchIndústria ceràmicaManagement of Technology and InnovationOperations managementFactoryQuality (business)Businessmedia_common
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Retrieving Open Source Software Licenses

2006

Open Source Software maintenance and reuse require identifying and comprehending the applied software licenses. This paper first characterizes software maintenance, and open source software (OSS) reuse which are particularly relevant in this context. The information needs of maintainers and reusers can be supported by reverse engineering tools at different information retrieval levels. The paper presents an automated license retrieval approach called ASLA. User needs, system architecture, tool features, and tool evaluation are presented. The implemented tool features support identifying source file dependencies and licenses in source files, and adding new license templates for identifying l…

Databasebusiness.industryComputer scienceSoftware developmentComputingMilieux_LEGALASPECTSOFCOMPUTINGStatic program analysisSoftware maintenanceSoftware licensecomputer.software_genreSoftware qualitySoftware constructionBackportingSoftware systembusinesscomputer
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ELECTRE III to dynamically support the decision maker about the periodic replacements configurations for a multi-component system

2013

The problem tackled by the present paper concerns the selection of the elements of a repairable and stochastically deteriorating multi-component system to replace (replacements configuration) during each scheduled and periodical system stop within a finite optimization cycle, by ensuring the simultaneous minimization of both the expected total maintenance cost and the system unavailability. To solve the considered problem, a combined approach between multi-objective optimization problem (MOOP) and multi-criteria decision making (MCDM) resolution techniques is proposed. In particular, the @e constraint method is used to single out the optimal Pareto frontier whereas the ELECTRE III multi-cri…

Decision support systemMathematical optimizationInformation Systems and ManagementOptimization problemComputer sciencePareto principleContext (language use)Multiple-criteria decision analysisMulti-objective optimizationManagement Information SystemsFrontierArts and Humanities (miscellaneous)Multi-objective optimization ELECTRE III periodic maintenance policy Multi-component system Non-homogeneous Poisson processSettore ING-IND/17 - Impianti Industriali MeccaniciDevelopmental and Educational PsychologyELECTRESettore ING-IND/16 - Tecnologie E Sistemi Di LavorazioneInformation SystemsDecision Support Systems
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A Digital Twin predictive maintenance framework of air handling units based on automatic fault detection and diagnostics

2022

The building industry consumes the most energy globally, making it a priority in energy efficiency initiatives. Heating, ventilation, and air conditioning (HVAC) systems create the heart of buildings. Stable air handling unit (AHU) functioning is vital to ensuring high efficiency and extending the life of HVAC systems. This research proposes a Digital Twin predictive maintenance framework of AHU to overcome the limitations of facility maintenance management (FMM) systems now in use in buildings. Digital Twin technology, which is still at an initial stage in the facility management industry, use Building Information Modeling (BIM), Internet of things (IoT) and semantic technologies to create…

Digita twinsDigita twinInternet of thingsAir handling unit performance assessment rulesMechanical EngineeringPredictive maintenanceBuilding and ConstructionVDP::Teknologi: 500Air handling unitAPARFacility managementElectrical and Electronic EngineeringAir handling unitsCivil and Structural Engineering
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Digital Transformation in Maintenance Management

2022

The relationship between technology and maintenance is mutually beneficial since technology is continuously improving with consequent substantial advancements in the field of maintenance. Maintenance management may be effectively modernized through digitalization. Developing advanced technologies promotes indeed the possibility of maintaining a competitive and long-term position in this field. Digitalization is consistently transforming organizations by allowing them to use suitable technologies for collecting data automatically. Various equipment and components are nowadays capable of collecting their operating data over an extended period, which may yield a plethora of intriguing insights…

Digitalisation Maintenance Management Data Collection Decision-Making FCM
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Santa Rosalia, the icon of biodiversity

2010

This article summarizes the results presented in a series of invited contributions which were submitted to celebrate the fiftieth anniversary of publication of the seminal article ‘‘Homage to Santa Rosalia or why are there so many kinds of animals’’ by G.E. Hutchinson. The authors were asked to explore old and new paradigms of biodiversity in aquatic ecosystems. The contributions by Hutchinson in this field are truly landmarks in the history of modern ecological sciences. The authors of the contributed articles, stimulated by one of the most fruitful concept articles in ecology that has appeared over the last half century, have shown that scientific investigation, although still seeking the…

Diversity maintenanceEcologymedia_common.quotation_subjectEcology (disciplines)BiodiversityAssemblage (composition)Environmental ethicsAquatic ScienceBiologyEcosystem servicesAquatic environmentCoexistence Predation Dispersal Competition Spatial heterogeneity Rare speciesIconcomputercomputer.programming_languageDiversity (politics)media_commonHydrobiologia
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Determination of Pareto frontier in multi-objective maintenance optimization

2011

Abstract The objective of a maintenance policy generally is the global maintenance cost minimization that involves not only the direct costs for both the maintenance actions and the spare parts, but also those ones due to the system stop for preventive maintenance and the downtime for failure. For some operating systems, the failure event can be dangerous so that they are asked to operate assuring a very high reliability level between two consecutive fixed stops. The present paper attempts to individuate the set of elements on which performing maintenance actions so that the system can assure the required reliability level until the next fixed stop for maintenance, minimizing both the globa…

DowntimeEngineeringOptimization problemOperations researchbusiness.industryConstrained optimizationPareto principleMulti-objective optimizationPreventive maintenanceIndustrial and Manufacturing EngineeringSpare partMaintenance actionsMaintenance optimization Multi-objective optimization Reliability Series–parallel systemsSafety Risk Reliability and QualitybusinessReliability Engineering & System Safety
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Proactive maintenance of offshore wind turbine blades using knowledge-based force analysis

2013

The operation and maintenance (O&M) costs of wind turbines constitute approximately 10-15% of the lifecycle cost in onshore installations and up to 30% in offshore installations. The O&M costs for offshore wind power plants are higher than the onshore ones due to greater logistical challenges of maintaining and servicing, and the less mature state of offshore wind energy technology. Wind turbine blades suffer from various faults, for example, blade angle asymmetry, icing, and bends. These faults may cause wind turbines to a standstill. Replacement of rotor blades will normally result in a long downtime since the replacement process involves heavy transportation (vessel, crane) and dependenc…

DowntimeWind powerTurbine bladeComputer sciencebusiness.industryTurbineWind engineeringlaw.inventionProactive maintenanceOffshore wind powerlawbusinessMarine engineeringIcingThird International Conference on Innovative Computing Technology (INTECH 2013)
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