Search results for "male infertility"
showing 10 items of 54 documents
Obesity and assisted reproductive technology outcomes.
2006
Obesity is a rising health problem in Western societies. It has been related to increased morbidity and mortality rates due to several pathologies. In the field of gynaecology and reproduction, obesity is associated with menstrual disorders, hirsutism, infertility, miscarriage and obstetric complications. It is known to impair human reproduction through different mechanisms such as insulin resistance, hyperandrogenism and elevated leptin levels. Weight management and dietary intervention can reverse this situation and improve reproductive function. Obesity can also impair the outcome of assisted reproductive technologies. The lower probability of a healthy live birth described in obese wome…
Reproductive System Outcome Among Patients with Polycystic Ovarian Syndrome.
2015
Polycystic ovarian syndrome (PCOS) may present with different clinical patterns and the anovulatory phenotype may not be the most common. Data suggest that anovulation in PCOS is not the consequence of increased androgen ovarian secretion but rather of a severe derangement of early follicle development. Other mechanisms may be operative in subgroups of patients and may contribute to the arrest of follicle growth and anovulation. At least 50% of anovulatory patients with PCOS become ovulatory in their late reproductive age. There is also evidence that menopause may occur later in women with PCOS. Finally, a strategy for treatment of infertility in PCOS is presented.
Ovarian stimulation for ovulation induction and in vitro fertilization in patients with systemic lupus erythematosus and antiphospholipid syndrome.
2008
Objective To review the current evidence regarding the relationship between systemic lupus erythematosus (SLE) and antiphospholipid syndrome and female infertility, as well as the risks associated with ovarian stimulation for ovulation induction and IVF. To establish, based on this information, guidelines for safe and successful assisted reproductive technology (ART). Design A MEDLINE computer search was performed to identify relevant articles. Result(s) Systemic lupus erythematosus and antiphospholipid syndrome are not related to infertility, except for cases of amenorrhea accompanying severe flares, renal insufficiency-related hypofertility, and ovarian failure secondary to cyclophosphami…
INFLAMMATORY BOWEL DISEASE AND INFGERTILITY: ANALYSIS OF LITERATURE AND FUTURE PERSPECTIVES
2021
Background: inflammatory bowel diseases (IBD) are chronic disorders that affect the gastrointestinal tract but which also present extraintestinal manifestations. One of the problems related to IBD is the presence of bothfemale and male infertility. Aim: determine the correlation between IBD and male and female infertility by analyzing the literature. Material and method: studies carried out in the last twenty years have been selected through the PubMed search engine. Only studies were selected that in their conclusions showed a real correlation between IBD and infertility. Results: the first cause of infetility in both sexes is related to the surgical interventions that patients have to fac…
Influencia de los distintos tipos y parámetros del ejercicio físico sobre la calidad seminal: una revisión sistemática de la literatura
2019
Es de sobra conocida la importancia positiva de la actividad fisica correctamente prescrita en terminos de intensidad y volumen sobre diferentes alteraciones metabolicas, osteomusculares, cognitivas, etc. La infertilidad es una patologia cuya epidemiologia esta al alza por los cambios en los habitos de nuestra vida cotidiana, como la dieta inadecuada o la radiacion de las nuevas generaciones de aparatos electricos. No existen demasiadas evidencias divulgativas sobre sus causas y efectos, asi como tampoco del papel del ejercicio en la reversion de sus sintomas. Con la finalidad de obtener y sintetizar la informacion mas relevante sobre la influencia de los diferentes tipos y parametros del e…
Body mass index and impact on semen quality of men attending an infertility clinic
2019
Background: The reproductive consequences of lifestyle factors in men are still controversial. In this prospective study, we verified the impact of body mass index alterations on semen parameters of patients who attended an infertility clinic. Materials and Methods: Semen samples from 156 subjects aged 22 to 53 years were analyzed. Smokers were categorized as mild (≤ 10 cigarettes/day), moderate (10-20 cigarettes/day”) and heavy smokers (> 20 cigarettes/day”). Men were grouped based upon calculated body mass index values (underweight, <18.5 Kg/m2; normal, 18.5-24.9 Kg/m2; overweight, 25-29.9 Kg/m2; obese, ≥ 30 Kg/m2). The data collected included patient height and weight, semen volume…
Clinical Pocketbook of Melatonin and CoQ10 in Male Infertility
2023
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The possible association of clusterin fucosylation changes with male fertility disorders
2021
AbstractIn the seminal plasma (n = 118) and serum (n = 90) clusterin (CLU) the fucosylation and the expression of selected fucosyltransferases (FUTs) were analyzed. Samples from infertile men were divided into groups based on the results of the standard semen analysis: normozoospermic (N), teratozoospermic (T), asthenoteratozoospermic (AT) and oligoasthenoteratozoospermic (OAT). The CLU fucosylation was analyzed using lectin-ELISAs with biotinylated lectins specific to α1,3-, α1,2-linked antennary fucose, and α1,6-linked core fucose (LTA, UEA, and LCA, respectively). The concentrations of FUT3 and FUT4, reflecting the expression of Le oligosaccharide structures, were measured using ELISA te…
Telomeres as a molecular marker of male infertility
2018
In recent years, male infertility has become a growing social problem. Standard diagnostic procedures, based on assessing seminological parameters, are often insufficient to explain the causes of male infertility. Because of this, new markers with better clinical application are being sought. One of the promising markers seems to be an assessment of telomere length of sperm. Sperm telomeres, in contrast to somatic cells, are elongated as men age. The results of some studies suggest that telomere length may be relevant in the case of fertilization and normal embryo development. Literature reports indicate that there is a correlation between telomere length of sperm and abnormal sperm paramet…
Nandrolone decanoate interferes with testosterone biosynthesis altering blood-testis barrier components
2017
Abstract The aim of this study was to investigate whether nandrolone decanoate (ND) use affects testosterone production and testicular morphology in a model of trained and sedentary mice. A group of mice underwent endurance training while another set led a sedentary lifestyle and were freely mobile within cages. All experimental groups were treated with either ND or peanut oil at different doses for 6 weeks. Testosterone serum levels were measured via liquid chromatography–mass spectrometry. Western blot analysis and quantitative real‐time PCR were utilized to determine gene and protein expression levels of the primary enzymes implicated in testosterone biosynthesis and gene expression leve…