Search results for "medium"

showing 10 items of 3746 documents

Tungsten(VI)-gluconic acid complexes: Polarimetric and13C-N.m.r. Studies in an excess of tungsten(VI)

1986

A polarimetric study of the tungsten (VI)-gluconic acid system in an excess of metal reveals the formation of four stable complexes: two monomers with 1 : 2 and 2: 1 stoichiometries and two dimers of 2:2 composition. The pH ranges of these species, the amount of acid equivalents their formation requires, and their conditional stability constants have also been calculated.

StereochemistryInorganic chemistryMetals and Alloyschemistry.chemical_elementTungstenCatalysisInorganic ChemistryMetalchemistry.chemical_compoundchemistryStability constants of complexesvisual_artAldonic acidMaterials Chemistryvisual_art.visual_art_mediumGluconic acidStoichiometryOrganometallic chemistryTransition Metal Chemistry
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Synthesis, characterization, X-ray crystallography, and antimicrobial activities of Ni(II) and Cu(II) complexes with a salicylaldehyde-based thiosemi…

2014

A new salicylaldehyde-based ‘ONS’ tridentate salicylaldehyde-N(4)-diethylthiosemicarbazone (H2SANEt2) has been synthesized and characterized by elemental analyses, mass, IR, and 1H NMR spectral parameters. The coordination mode of the synthesized ligand is reported by solid state isolation and physico-chemical identification of Ni(II) and Cu(II) complexes, [Ni(SANEt2)]2 (1) and [Cu(SANEt2)]2 (2). Both complexes are neutral and oxygen-bridged dinuclear species. The ligand is bideprotonated ‘ONS’ tridentate in both complexes. IR spectral data indicate that coordination of each metal of the two complexes occurs through phenolic oxygen, azomethine nitrogen, and thiolato sulfur. X-ray crystallog…

StereochemistryLigandChemistryCrystal structureMetalCrystallographychemistry.chemical_compoundSalicylaldehydevisual_artX-ray crystallographyMaterials Chemistryvisual_art.visual_art_mediumProton NMRPhysical and Theoretical ChemistrySemicarbazoneMonoclinic crystal systemJournal of Coordination Chemistry
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Coordination properties of imino(2-pyridyl)methylpalladium(II) compounds. Preparation and thermal rearrangement of binuclear adducts with palladium(I…

1988

Abstract The imino(2-pyridyl)methylpalladium(II) compound py-2-C(R′)NR (R = C 6 H 4 OMe-p, R′ = trans-PdCl(PPh 3 ) 2 ) reacts with [PdCl 2 (CH 2 CHPh)] 2 , [PdCl 2 - (NCMe) 2 ], and K[PtCl 3 (CH 2 CH 2 )] to give binuclear complexes [MCl 2 {py-2- C(R′)NR}] (M = Pd, Pt), in which the α-diimino group acts as a chelating bidentate ligand. In hot 1,2-dichloroethane, these complexes undergo a PPh 3 and chloride ligand exchange at rates which depend markedly on the metal M (Pd ⪢ Pt), to yield the new derivatives [MCl(PPh 3 ){py-2-C(cis-PdCl 2 (PPh 3 ))NR}]. The ligand exchange is followed by a much slower decomposition to [MCl 2 (PPh 3 ) 2 ]. Labile intermediates of the same type, [MCl(PPh …

StereochemistryLigandOrganic ChemistryThermal decompositionchemistry.chemical_elementBiochemistryMedicinal chemistryAdductInorganic ChemistryMetalchemistryvisual_artYield (chemistry)Materials Chemistryvisual_art.visual_art_mediumChelationPhysical and Theoretical ChemistryPlatinumPalladiumJournal of Organometallic Chemistry
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Synthesis of a Linear Assembly Consisting of a Central Ru(Phen)32+ Derivative and Two Peripheral Porphyrins

2002

A ruthenium(II) precursor complex containing a bis-phenanthroline ligand, leading to a controlled helical structure around the metal centre, and a third phenanthroline-type ligand has been prepared. The spatial arrangement of the system is such that two chemical groups are disposed trans to one another on an axis running through the Ru centre. By appropriate functional group transformation, these two groups can be attached to monosubstituted zinc(II) porphyrins (PZn) to afford a linear array consisting of a central ruthenium(II) complex and two peripheral PZn motifs. (© Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002)

StereochemistryLigandOrganic Chemistrychemistry.chemical_elementZincLinear arrayRutheniumMetalchemistry.chemical_compoundCrystallographychemistryvisual_artFunctional groupChemical groupsvisual_art.visual_art_mediumPhysical and Theoretical ChemistryDerivative (chemistry)European Journal of Organic Chemistry
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Conformations and coordination schemes of carboxylate and carbamoyl derivatives of the tetraazamacrocycles cyclen and cyclam, and the relation to the…

1998

Abstract This paper discusses and rationalizes the metal coordination pattern of 12- and 14-membered tetraazamacrocyclic carboxylate and carbamoyl ligands based on the cyclen and cyclam framework in light of their acido–basic properties. Structural and protonation data are reviewed in order to illustrate the influence of the free ligand's protonation state and of the pH conditions during the complexation reaction on the final coordination mode of the metallic cations.

StereochemistryLigandProtonationInorganic ChemistryMetalchemistry.chemical_compoundCrystallographychemistryCyclenvisual_artCyclamMaterials Chemistryvisual_art.visual_art_mediumCarboxylatePhysical and Theoretical ChemistryCoordination Chemistry Reviews
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Triplet of cysteines – Coordinational riddle?

2020

Polythiol binding of metal ions plays crucial role in the proper functioning of cysteine-rich proteins that are responsible for metal homeostasis and defending processes against metal toxicity (including heavy metals detoxification). The coordination properties of cysteine residues involved in specific sequencional patterns in proteins (like those present in e.g. metallothioneins) are interesting not only from a chemical point of view but may also lead to a better understanding of the purpose and allocation of metal ions in various biomolecules. In this study, the interaction of Zn2+, Cd2+ and Ni2+ ions with four peptides containing cysteine triplet motif were studied by potentiometric and …

StereochemistryMetal ions in aqueous solutionMetal toxicity010402 general chemistry01 natural sciencesBiochemistryInorganic ChemistryMetalResidue (chemistry)chemistry.chemical_compoundCoordination ComplexesNickelAmideHumansCysteinechemistry.chemical_classification010405 organic chemistryBiomoleculePeptide Fragments0104 chemical sciencesZincchemistryvisual_artThiolvisual_art.visual_art_mediumMetallothioneinCadmiumCysteineJournal of Inorganic Biochemistry
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Bimetallic Complexes from Amphoteric Group 13/15 Ligands: Syntheses and X-ray Crystal Structures

2002

Bimetallic, pentel-bridged complexes of the type [(dmap)Me 2 -M-E(SiMe 3 ) 2 -M'(CO) n ] (M = Al, Ga; E=P, As, Sb; M'=Cr, Fe, Ni; DMAP= 4-(dimethylamino)pyridine) are formed by reactions of DMAP-coordinated monomeric Group 13/15 compounds [(dmap)Me 2 M-E(SiMe 3 ) 2 ] with the transition metal complexes [(Me 3 N)Cr-(CO) 5 ], [Fe 3 (CO) 1 2 ], and [Ni(CO) 4 ]. For the first time, this reaction offers a general pathway to compounds containing a Group 13 metal and a transition metal bridged by a pentel atom. Complexes prepared in this way were characterized by IR and multinuclear NMR spectroscopy and by single-crystal X-ray structure analysis. Their electronic and structural properties are disc…

StereochemistryOrganic ChemistryGeneral ChemistryCrystal structureNuclear magnetic resonance spectroscopyCatalysisMetalCrystallographychemistry.chemical_compoundMonomerMain group elementchemistryTransition metalvisual_artPyridinevisual_art.visual_art_mediumBimetallic stripChemistry - A European Journal
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Aerobic epoxidation of olefins catalysed by square-planar cobalt(III) complexes of bis-N,N′-disubstituted oxamides and related ligands

1997

The new square-planar nickel(II) complexes of o-phenylenebis(N′-methyloxamidate) and related ligands catalyse the aerobic epoxidation of olefins with co-oxidation of pivalaldehyde; the modulation of catalytic activity by substituents along this series of metal complexes points out the role of high-valent nicke(IV)-oxo species as the putative intermediate in these oxygen atom transfer reactions.

StereochemistryOrganic Chemistrychemistry.chemical_elementBiochemistryMedicinal chemistryCatalysisMetalNickelOxygen atomchemistryvisual_artDrug Discoveryvisual_art.visual_art_mediumCobaltTetrahedron Letters
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Furoquinolines and dihydrooxazole alkaloids with cytotoxic activity from the stem bark of Araliopsis soyauxii.

2018

Abstract Two new furoquinoline alkaloids, maculine B (1) and kokusaginine B (2) and one new dihydrooxazole alkaloid, veprisazole (3), along with four known compounds namely, N13-methyl-3-methoxyrutaecarpine (4), flindersiamine (5), skimmianine (6) and tilianin (7) were isolated from the methanol extract of the stem bark of Araliopsis soyauxii Engl. by various chromatographic methods. Their structures were determined using spectrometry and spectroscopic techniques including NMR and MS. The cytotoxicity of the new compounds compared to that of doxorubicin, the reference anticancer compound, was determined on a panel of nine cancer cell lines including sensitive and drug resistant phenotypes. …

StereochemistryPhytochemicalsDioxoles01 natural sciencesAlkaloidsCell Line TumorDrug DiscoverymedicineCytotoxic T cellHumansDoxorubicinCameroonGlycosidesMedicinal plantsCytotoxicityFuransIC50RutaceaePharmacologyFlavonoidsMolecular Structure010405 organic chemistryChemistryAlkaloidGeneral MedicineAntineoplastic Agents PhytogenicDrug Resistance Multiple0104 chemical sciences010404 medicinal & biomolecular chemistryCell cultureDrug Resistance Neoplasmvisual_artvisual_art.visual_art_mediumPlant BarkQuinolinesBarkmedicine.drugFitoterapia
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Rotenoids, Flavonoids, and Chalcones from the Root Bark of Millettia usaramensis.

2015

Five new compounds, 4-O-geranylisoliquiritigenin (1), 12-dihydrousararotenoid B (2), 12-dihydrousararotenoid C (3), 4'-O-geranyl-7-hydroxyflavanone (4), and 4'-O-geranyl-7-hydroxydihydroflavanol (5), along with 12 known natural products (6-17) were isolated from the CH2Cl2/MeOH (1:1) extract of the root bark of Millettia usaramensis ssp. usaramensis by chromatographic separation. The purified metabolites were identified by NMR spectroscopic and mass spectrometric analyses, whereas their absolute configurations were established on the basis of chiroptical data and in some cases also by X-ray crystallography. The crude extract was moderately active (IC50 = 11.63 μg/mL) against the ER-negative…

StereochemistryPlasmodium falciparumMolecular ConformationPharmaceutical Scienceroot barkCrystallography X-Ray01 natural sciencesMillettiaAnalytical ChemistryMillettia usaramensischemistry.chemical_compoundAntimalarialsChalconesDrug DiscoveryPlant BarkHumansta116IC50Nuclear Magnetic Resonance Biomolecularta317metabolitesPharmacologyFlavonoidsChromatographyNatural productbiologyMolecular Structure010405 organic chemistryChemistryPlant ExtractsOrganic ChemistryPlasmodium falciparumChloroquinebiology.organism_classification0104 chemical sciencesMillettia010404 medicinal & biomolecular chemistryChromatographic separationHEK293 CellsComplementary and alternative medicinevisual_artFlavanonesvisual_art.visual_art_mediumPlant BarkMolecular MedicineBarkrotenoidsJournal of natural products
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