Search results for "mening"

showing 10 items of 254 documents

Relevance of gamma interferon, tumor necrosis factor alpha, and interleukin-10 gene polymorphisms to susceptibility to Mediterranean spotted fever.

2009

Several studies have demonstrated that cellular immunity plays a critical role in the protective immune response against Rickettsia conorii. Immune CD4+ and CD8+ T cells are both involved in the control of rickettsial infection (38). Perivascular infiltrated CD4+ and CD8+ T lymphocytes, macrophages, and natural killer cells produce chemokines and cytokines that activate endothelial rickettsicidal activities. Infected human cells, including endothelial cells, hepatocytes, and macrophages, activated by gamma interferon (IFN-γ), tumor necrosis factor alpha (TNF-α), and interleukin-1β (IL-1β), kill intracellular rickettsiae by one or a combination of three mechanisms, involving nitric oxide syn…

AdultMaleMicrobiology (medical)Meningitidesgene polymorphismgene polymorphisms; mediterranean spotted fevermedicine.medical_treatmentClinical BiochemistryImmunologyBiologyBoutonneuse FeverPolymorphism Single NucleotideInterferon-gammaImmune systemInterferonmedicineHumansImmunology and AllergyCytotoxic T cellSicilyTumor Necrosis Factor-alphaMiddle AgedInterleukin-10mediterranean spotted feverInterleukin 10CytokineImmunologyFemaleTumor necrosis factor alphaDisease SusceptibilityMicrobial ImmunologyCD8medicine.drug
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Do spinal meningiomas penetrate the pial layer? Correlation between magnetic resonance imaging and microsurgical findings and intracranial tumor inte…

1997

OBJECTIVE: To study the relationships between spinal dura-arachnoid and tumor-cord interfaces in spinal meningiomas and to investigate whether a disruption of the pial layer and penetration of the tumor in the spinal cord occurs. METHODS: Fifteen patients with histologically proven meningiomas underwent magnetic resonance imaging (MRI) preoperatively. All patients underwent microsurgery. The histological characteristics of the tumors were compared with MRI and microsurgical findings. RESULTS: At surgery, the peritumoral hypointense rim revealed by MRI in 10 of 15 patients corresponded to a well-defined cerebrospinal fluid-containing space confined between the outer arachnoidal layer and the…

AdultMaleMicrosurgeryPathologymedicine.medical_specialtyDura materBrain tumorMeningiomaMeningeal NeoplasmsmedicineHumansNeoplasm InvasivenessSpinal Meningesbusiness.industrySettore MED/27 - NeurochirurgiaLeptomeningesSpinal meningiomas tumor interfacesAnatomyMiddle AgedSpinal cordmedicine.diseaseMagnetic Resonance Imagingnervous system diseasesmedicine.anatomical_structureArachnoid materPia MaterFemaleSurgeryNeurology (clinical)ArachnoidSubarachnoid spaceMeningiomabusiness
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Giant olfactory groove meningiomas: extent of frontal lobes damage and long-term outcome after the pterional approach.

2010

The treatment of giant olfactory groove meningiomas (OGMs; maximum diameter ≥ 6 cm) poses special problems and represents a surgical challenge. We discuss the long-term results in a series of 18 patients with giant OGMs and report our experience on a global strategy encompassing the pterional approach to manage the lesion and an extended transbasal approach to treat recurrences.Between February 1991 and December 2007, 18 patients with giant OGMs were surgically managed via a pterional craniotomy. Postoperative follow-up imaging was obtained at one, six, and 12 months and then yearly. In preoperative images, data from tumor volume were assessed. The volume of the residual right frontal poren…

AdultMaleMicrosurgerymedicine.medical_specialtymedicine.medical_treatmentFluid-attenuated inversion recoveryNeurosurgical ProceduresMeningiomaOlfactory groovePterional approachLesionMeningiomaPostoperative ComplicationsOlfactory Groove MeningiomamedicineHumansOlfactory GrooveAgedmedicine.diagnostic_testbusiness.industryMagnetic resonance imagingOlfactory PathwaysMiddle AgedMicrosurgeryNeurovascular bundlemedicine.diseaseLong-Term CareMagnetic Resonance ImagingFrontal LobeSurgeryTreatment OutcomeFemaleSurgeryNeurology (clinical)medicine.symptomMeningiomaTomography X-Ray ComputedbusinessFollow-Up Studies
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Radiofrequency electromagnetic fields emitted from base stations of DECT cordless phones and the risk of glioma and meningioma (Interphone Study Grou…

2006

The objective of this study was to test the hypothesis that exposure to continuous low-level radiofrequency electromagnetic fields (RF EMFs) increases the risk of glioma and meningioma. Participants in a population-based case-control study in Germany on the risk of brain tumors in relation to cellular phone use were 747 incident brain tumor cases between the ages of 30 and 69 years and 1494 matched controls. The exposure measure of this analysis was the location of a base station of a DECT (Digital Enhanced Cordless Telecommunications) cordless phone close to the bed, which was used as a proxy for continuous low-level exposure to RF EMFs during the night. Estimated odds ratios were 0.82 (95…

AdultMaleNeoplasms Radiation-InducedPopulationBiophysicsRisk AssessmentMeningiomaBase stationElectromagnetic FieldsRisk FactorsGliomaGermanyCordless phoneMedicineHumansRadiology Nuclear Medicine and imagingeducationMicrowavesAgedProportional Hazards Modelseducation.field_of_studyRadiationbusiness.industryBrain NeoplasmsIncidenceDigital Enhanced Cordless TelecommunicationsEnvironmental ExposureGliomaMiddle Agedmedicine.diseaseCase-Control StudiesFemaleCell PhonesbusinessNuclear medicineMeningiomaCell Phone
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Medical exposure to ionising radiation and the risk of brain tumours: Interphone study group, Germany

2007

Abstract Background The role of exposure to low doses of ionising radiation in the aetiology of brain tumours has yet to be clarified. The objective of this study was to investigate the association between medically or occupationally related exposure to ionising radiation and brain tumours. Methods We used self-reported medical and occupational data collected during the German part of a multinational case–control study on mobile phone use and the risk of brain tumours (Interphone study) for the analyses. Results For any exposure to medical ionising radiation we found odds ratios (ORs) of 0.63 (95% confidence interval (CI) = 0.48–0.83), 1.08 (95% CI = 0.80–1.45) and 0.97 (95% CI = 0.54–1.75)…

AdultMaleOncologyCancer Researchmedicine.medical_specialtyNeoplasms Radiation-Inducedaetiologymedicine.medical_treatmentcase-control studyAcoustic neuromaMeningiomaElectromagnetic FieldsGermanyOccupational ExposureRadiation IonizingInternal medicineGliomaEpidemiologyotorhinolaryngologic diseasesmedicineHumansrisk factorsRisk factorAgedBrain Neoplasmsbusiness.industryionising radiationbrain tumoursCase-control studyOdds ratioMiddle Agedmedicine.diseaseRadiation therapyOncologyCase-Control StudiesFemaleepidemiologybusinessNuclear medicineCell Phone
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Cellular Phones, Cordless Phones, and the Risks of Glioma and Meningioma (Interphone Study Group, Germany)

2006

The widespread use of cellular telephones has generated concern about possible adverse health effects, particularly brain tumors. In this population-based case-control study carried out in three regions of Germany, all incident cases of glioma and meningioma among patients aged 30–69 years were ascertained during 2000–2003. Controls matched on age, gender, and region were randomly drawn from population registries. In total, 366 glioma cases, 381 meningioma cases, and 1,494 controls were interviewed. Overall use of a cellular phone was not associated with brain tumor risk; the respective odds ratios were 0.98 (95% confidence interval (CI): 0.74, 1.29) for glioma and 0.84 (95% CI: 0.62, 1.13)…

AdultMaleOncologymedicine.medical_specialtyEpidemiologyPopulationBrain tumorRisk AssessmentInterviews as TopicMeningiomaElectromagnetic FieldsRisk FactorsGermanyGliomaInternal medicineCordless phonemedicineHumansRegistriesRisk factoreducationneoplasmsAgededucation.field_of_studyBrain Neoplasmsbusiness.industryIncidenceCase-control studyEnvironmental ExposureGliomaOdds ratioMiddle Agedmedicine.diseasenervous system diseasesSurgerycellular phoneCase-Control StudiestelephoneFemaleMeningiomaRisk assessmentbusinessCell PhoneAmerican Journal of Epidemiology
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Antimeningococcal and antipneumococcal vaccination determinants: A European systematic literature review

2015

Background. ESCULAPIO is a multicenter project, funded by the Italian Centre for Disease Prevention and Control, aimed at implementing communication strategies to improve vaccination knowledge and attitudes among different target populations. Objective. The objective of the Sicilian research unit was, in the first phase, to identify, through systematic literature revision, which vaccination determinants play a role in the uptake of recommended vaccines included in the Italian Vaccination Plan. Design. A systematic literature review was carried out on studies describing the determinants underlying pneumococcal and meningococcal vaccination uptake. The analysis was limited to papers published…

AdultMaleParentsHealth Knowledge Attitudes PracticeAdolescentMeningococcal VaccinesSettore MED/42 - Igiene Generale E ApplicataVulnerable PopulationsHealth Services AccessibilityPneumococcal InfectionsPneumococcal VaccinesVaccination RefusalMeningococcal vaccination; Pneumococcal vaccination; Systematic literature review; Epidemiology; Public Health Environmental and Occupational HealthHumanssystematic literature review meningococcal vaccination pneumococcal vaccinationChildAgedAged 80 and overVaccinationAge FactorsInfantEuropeMeningococcal InfectionsSocioeconomic FactorsChild PreschoolCosts and Cost AnalysisFemale
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Electrophysiological and MRI findings in 2 patients with Listeria rhombencephalitis.

1997

AdultMalePathologymedicine.medical_specialtyElectrodiagnosisMeningitis Listeriamedicine.disease_causeCentral nervous system diseaseListeria monocytogenesmedicineEvoked Potentials Auditory Brain StemHumansListeriosismedicine.diagnostic_testbiologyBlinkingReflex Abnormalbusiness.industrymedicine.diseasebiology.organism_classificationPrognosisMagnetic Resonance ImagingElectrophysiologyNeurologyListeriaEncephalitisFemaleNeurology (clinical)businessMri findingsEncephalitisBrain StemEuropean neurology
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Eosinophilic Meningitis due toAngiostrongylus cantonensisin Germany

2009

We report a case of eosinophilic meningitis due to Angiostrongylus cantonensis in a patient who returned from Thailand. The presence of a compatible epidemiologic history and eosinophilia in cerebrospinal fluid (CSF) lead to the diagnosis, which was confirmed by detection of specific antibodies. After treatment with albendazole and corticosteroids he recovered completely.

AdultMalePathologymedicine.medical_specialtyEosinophilic MeningitisBlotting WesternAlbendazoleAlbendazoleCerebrospinal fluidAdrenal Cortex HormonesGermanyEosinophiliamedicineAnimalsHumansEosinophiliaHelminthsMeningitisCerebrospinal FluidStrongylida InfectionsAnthelminticsTravelbiologybusiness.industryAngiostrongylus cantonensisGeneral MedicineThailandbiology.organism_classificationmedicine.diseaseAngiostrongylus cantonensisSpecific antibodyImmunologymedicine.symptombusinessMeningitismedicine.drugJournal of Travel Medicine
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The spontaneous burst activity of peripheral blood monocytes in patients with acute polyradiculoneuritis, lymphocytic meningoencephalitis, and multip…

1986

Abstract The course of the spontaneous burst activity (BA) of peripheral blood monocytes was examined in patients with acute polyradiculoneuritis (PN), lymphocytic meningoencephalitis (LE), and multiple sclerosis (MS) and the BA was compared with the clinical course. In 4 patients with postinfectious acute PN the BA was significantly increased up to values around 60000 counts/10 s. The BA and the clinical course were closely correlated in these patients (mean of r = 0.83). In 4 patients with lymphocytic LE the BA initially was moderately increased to values between 4000 and 5000 counts/10 s and showed again a very close correlation with the clinical course (mean of r = 0.99) In 13 MS patien…

AdultMalePathologymedicine.medical_specialtyMultiple SclerosisAdolescentPolyradiculoneuropathySigns and symptomsMonocytesMeningoencephalitisHumansMedicineIn patientLymphocytesbusiness.industryMultiple sclerosisClinical courseMiddle Agedmedicine.diseasePeripheral bloodLymphocytic meningoencephalitisNeurologyAcute DiseaseLuminescent MeasurementsFemaleNeurology (clinical)businessJournal of the Neurological Sciences
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