Search results for "mesoangioblasti"
showing 5 items of 5 documents
Metalloproteasi nella biologia dei mesoangioblasti di topo
2011
Meccanismo di rilascio di Hsp70 tramite vescicole di membrana e suo ruolo nella migrazione di cellule staminali di topo
2014
Mouse mesoangioblast are vessel-derived stem cells which are able to differentiate in most mesodermal tissues, and have also the ability to migrate and cross the endothelial barrier. In our previous work we have demonstrated that these cells release in the extracellular medium membrane vesicles containing matrix metalloproteinases MMP-2 and MMP-9. We have also demonstrated that they express Hsp70 under basal growth condition. According to literature data, the aim of this study was to investigate the possible role of Hsp70 on MMPs regulation. To do this we compared mesoangioblasts A6 cell clone with two other cell clones: NM3, partially knockdown for Hsp70 expression and a cell clone overexp…