Search results for "method"

Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy

2015

ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.

Effect of RNS60 in amyotrophic lateral sclerosis: a phase II multicentre, randomized, double-blind, placebo-controlled trial

2022

Background and purpose: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with limited treatment options. RNS60 is an immunomodulatory and neuroprotective investigational product that has shown efficacy in animal models of ALS and other neurodegenerative diseases. Its administration has been safe and well tolerated in ALS subjects in previous early phase trials. Methods: This was a phase II, multicentre, randomized, double-blind, placebo-controlled, parallel-group trial. Participants diagnosed with definite, probable or probable laboratory-supported ALS were assigned to receive RNS60 or placebo administered for 24 weeks intravenously (375 ml) once a week and via nebul…

Analyzing of main trends of STEM-education in Ukraine using stemua.science statistics

2020

t. STEM-education is a modern effective approach that nowadays can be interpreted in very different ways and it even has some modification (STEM/STEAM/STREAM). Anyway, the “New Ukrainian school” concept includes approaches similar to STEM-education. However, there wasn’t analyzed the current state of STEM-education in Ukraine. We propose to analyses it by using SEO analysis of one of the most popular STEM-oriented cloud environment in Ukraine stemua.science. It is proposed to use the cycle for cloud-based educational environments (publishing/SEO analysis/team’s brainstorm/prediction/creation of further plan) to improve their efficiency. It is found, that STEM-based and traditional publicati…

Nowa szkolna polonistyka czy powrót do źródeł? Rozważania o kształceniu literackim we współczesnej szkole

2018

Pytanie o „starą" i „nową" polonistykę szkolną jest wciąż aktualne. Pojawia się w wielu dyskusjach na temat polonistycznego kształcenia. Namysł nad nim prowadzi do kilku spostrzeżeń: uczenie literatury, uczenie odbioru tekstu zasadza się na wartościach stałych i niezbywalnych; jest procesem; stwarza czytelnika, ale przede wszystkim człowieka. Cele formacyjne są ważne i nie da się ich zastąpić modnymi hasłami, tak jak nie da się odejść od rozumnego czytania, odbioru tekstu. Można wykorzystywać jedynie metody bliższe uczniowi, „nowe" lub "przenicowane", dostosowane do danego czasu. Polonistyczny warsztat może być wzbogacony o nowe narzędzia. Jednak podstawowy „korpus" ma charakter ponadczasow…

Language teacher identities as socio-politically situated construction : Finnish and Brazilian student teachers’ visualisations of their professional…

2021

The process of envisioning the future is central to teachers’ identity construction, but different environments create distinct sociocultural conditions for the process. This qualitative study drawing on visual-textual methods compares Finnish and Brazilian student teachers’ desired and feared professional futures. Two different perspectives on future identities were detected: a desire for status and a desire for meaningfulness. The results revealed the radically different social status of teaching in the two countries and the role this played in the envisioned identities. The study highlights the importance of awareness of the socio-political nature of identity construction in developing t…

The Effects of Consumer Demographics and Payment Method Preference on Product Return Frequency and Reasons in Online Shopping

2021

In online shopping, product returns are very common. In order to reduce them, one must first understand who are making them and why are they being made. In this study, we aim to address these questions by examining product return behaviour from a consumer-centric rather than the more traditional product-centric, retailer-centric, and order-centric perspectives. More specifically, we focus on the effects of four demographic characteristics of consumers (i.e., gender, age, education, and income) as well as their payment method preference on their product return frequency and product return reasons. As the data, we use the responses from 560 Finnish online consumers, which were collected with …

Test-retest reliability of selected items of Health Behaviour in School-aged Children (HBSC) survey questionnaire in Beijing, China

2010

Abstract Background Children's health and health behaviour are essential for their development and it is important to obtain abundant and accurate information to understand young people's health and health behaviour. The Health Behaviour in School-aged Children (HBSC) study is among the first large-scale international surveys on adolescent health through self-report questionnaires. So far, more than 40 countries in Europe and North America have been involved in the HBSC study. The purpose of this study is to assess the test-retest reliability of selected items in the Chinese version of the HBSC survey questionnaire in a sample of adolescents in Beijing, China. Methods A sample of 95 male an…

Bacterial nitrogen fixation in boreal mosses

2013

Kokemuksellisuus työelämässä organisaatioestetiikan viitekehyksessä : työntekijöiden subjektiiviset konstruktiot tehokkuudesta

2014

Search for photons with energies above 1018 eV using the hybrid detector of the Pierre Auger Observatory

2017

A search for ultra-high energy photons with energies above 1 EeV is performed using nine years of data collected by the Pierre Auger Observatory in hybrid operation mode. An unprecedented separation power between photon and hadron primaries is achieved by combining measurements of the longitudinal air-shower development with the particle content at ground measured by the fluorescence and surface detectors, respectively. Only three photon candidates at energies 1-2 EeV are found, which is compatible with the expected hadron-induced background. Upper limits on the integral flux of ultra-high energy photons of 0.027, 0.009, 0.008, 0.008 and 0.007 km-2 sr-1 yr-1 are derived at 95% C.L. for ener…