Search results for "methods"
showing 10 items of 4526 documents
A mathematical model for the therapy of the HIV infection
2005
In this paper we consider the evolution of the HIV infection under a highly effective treatment based on a combination of RTI and/or PI drugs. This is usually modelled with a set of ODEs where the drug efficacy is a constant. In this paper we consider the treatment efficacy as a dynamic variable which evolves during the treatment. To model the dynamics of the drug efficacy we use an evolutive type assumption. The resulting set of ODEs are able to reproduce the typical pattern of the illness evolution under treatment: a period of remission, which can last several years, followed by a progressive recrudescence and a viral rebound.
Effects of different lower-limb sensory stimulation strategies on postural regulation-a Systematic review and metaanalysis
2017
Systematic reviews of balance control have tended to only focus on the effects of single lower-limb stimulation strategies, and a current limitation is the lack of comparison between different relevant stimulation strategies. The aim of this systematic review and meta-analysis was to examine evidence of effects of different lower-limb sensory stimulation strategies on postural regulation and stability. Moderate- to high-pooled effect sizes (Unbiased (Hedges' g) standardized mean differences (SMD) = 0.31-0.66) were observed with the addition of noise in a Stochastic Resonance Stimulation Strategy (SRSS), in three populations (i.e., healthy young adults, older adults, and individuals with low…
EDGE: explorer of diffuse emission and gamma-ray burst explosions
2009
How structures on various scales formed and evolved from the early Universe up to present time is a fundamental question of astrophysical cosmology. EDGE will trace the cosmic history of the baryons from the early generations of massive star by Gamma-Ray Burst (GRB) explosions, through the period of cluster formation, down to very low redshifts, when between a third and one half of the baryons are expected to reside in cosmic filaments undergoing gravitational collapse by dark matter (Warm Hot Intragalactic Medium: WHIM). In addition EDGE, with its unprecedented observational capabilities, will provide key results on several other topics. The science is feasible with a medium class mission …
The contribution of human migration to tourism: The VFR travel between the EU28 member states
2017
This study explores the correlation between human migration and that part of tourism due to people visiting friends and relatives in a foreign country. We first compared the network structure of migration stocks and tourism flows between the 28 member countries of the European Union over the period 2000–2012. Then, we performed several econometric analyses to study the main tourism determinants and the correlations between migration to tourism. The paper derives from the discussion of the results an estimate of the contribution to the overall tourism phenomenon due to visiting friends and relatives. Complex network analysis and gravity models were the investigation methods preferred.
Cybertext Challenge
2007
This article discusses the changing role of literature in the contemporary media landscape. Literary scholarship may well maintain its importance in the digitalizing world, but this requires it to engage in an open dialogue with cultural and media studies. It is important that more attention is paid to contemporary literature as well as to new media offering significant pedagogical possibilities, which should be better acknowledged. The article's main focus is on the emerging field of digital literature. Cybertextuality, especially, is fundamentally changing our notions of the integrity of a literary work, reading, writing and interpretation. I attempt to describe and put into context one …
Changes in visual function and retinal structure in the progression of Alzheimer's disease
2019
Background Alzheimer's Disease (AD) can cause degeneration in the retina and optic nerve either directly, as a result of amyloid beta deposits, or secondarily, as a result of the degradation of the visual cortex. These effects raise the possibility that tracking ophthalmologic changes in the retina can be used to assess neurodegeneration in AD. This study aimed to detect retinal changes and associated functional changes in three groups of patients consisting of AD patients with mild disease, AD patients with moderate disease and healthy controls by using non-invasive psychophysical ophthalmological tests and optical coherence tomography (OCT). Methods We included 39 patients with mild AD, 2…
Attempt to Construct a Scale for the Measurement of the Effect of Suggestion on Perception1
1975
A scale based on experimental methods has been prepared for measuring the effects of indirect suggestion upon perception. Three categories are included: (1) distorting the interpretation of presented stimuli, (2) inducing sense-impressions in the absence of adequate stimuli, and (3) producing insensitivity to stimuli that are objectively present. Test situations were designed for tactual, auditory, and visual perception. The scale was tested on a sample of 112 students from the 11th and 12th grades of a large city high school (58 girls and 54 boys). Most of the item intercorrelations were positive and many significantly so. Eliminating the 9 lowest items of 21 left 12 for a reduced matrix,…
Fillets:Cues for connections in Focus+Context views of graph-like diagrams
2003
We apply fillets-smoothing of sharp angles at the joints-between the connections and nodes of graph-like diagrams. In situations where the graph layout is constrained, e.g. Focus+Context views or views where the coordinates of the nodes are informative, fillets can clarify the relationships considerably without altering the layout. A visual search experiment supports our hypothesis that with fillets it is considerably easier to perceive node-connection structures. We discuss algorithms with different tradeoffs for flexibility and performance for rendering these connections in a single pass using OpenGL.
CheS-Mapper 2.0 for visual validation of (Q)SAR models
2014
Abstract Background Sound statistical validation is important to evaluate and compare the overall performance of (Q)SAR models. However, classical validation does not support the user in better understanding the properties of the model or the underlying data. Even though, a number of visualization tools for analyzing (Q)SAR information in small molecule datasets exist, integrated visualization methods that allow the investigation of model validation results are still lacking. Results We propose visual validation, as an approach for the graphical inspection of (Q)SAR model validation results. The approach applies the 3D viewer CheS-Mapper, an open-source application for the exploration of sm…
Visualizations for Decision Support in Scenario-based Multiobjective Optimization
2021
Reproducibility artifacts for: Babooshka Shavazipour, Manuel López-Ibáñez, and Kaisa Miettinen. Visualizations for Decision Support in Scenario-based Multiobjective Optimization. Information Sciences, 2021. doi:10.1016/j.ins.2021.07.025. Abstract: We address challenges of decision problems when managers need to optimize several conflicting objectives simultaneously under uncertainty. We propose visualization tools to support the solution of such scenario-based multiobjective optimization problems. Suitable graphical visualizations are necessary to support managers in understanding, evaluating, and comparing the performances of management decisions according to all objec…