Search results for "miR"

Almodóvar, una población de la Cora de Tudmir sepultada en las dunas de Gardamar de Segura

1985

Nemirstības fenomens: ķīniešu tradicionālā ģeomantija (fenšui) un tās iezīmes Ķīnas pirmā imperatora Cjiņ Šihuan kapeņu celtniecībā

2021

Maģistra darba tēma ir „Nemirstības fenomens: ķīniešu tradicionālā ģeomantija (fenšui) un tās iezīmes Ķīnas pirmā imperatora Cjiņ Šihuan kapeņu celtniecībā”. Cjiņ Šihuan ievērojamākais celtniecības projekts bija kapenes un terakotas armija, kas speciāli tika veidotas, lai sasniegtu nemirstību. Fenšui sākotnēji izmantoja tieši ideālās kapa vietas atrašanai. Tas bija uzmanīgi glabāts noslēpums un sākotnēji pieejams tikai valdošajai elitei. Fenšui jēdziens mūsdienās ir ļoti izplatīts visā pasaulē, bet tas tiek lietots pārāk plaši un nekonkrēti. Līdz ar to Rietumos cilvēkiem bieži vien pat nav pareizas izpratnes, ko tas īsti nozīmē, vai kāda bijusi tā sākotnējā nozīme Ķīnā. Tāpēc ir svarīgi par…

Pseudocomplements in sum-ordered partial semirings

2007

We study a particular way of introducing pseudocomplementation in ordered semigroups with zero, and characterise the class of those pseudocomplemented semigroups, termed g-semigroups here, that admit a Glivenko type theorem (the pseudocomplements form a Boolean algebra). Some further results are obtained for g-semirings – those sum-ordered partially additive semirings whose multiplicative part is a g-semigroup. In particular, we introduce the notion of a partial Stone semiring and show that several well-known elementary characteristics of Stone algebras have analogues for such semirings.

Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation.

2014

Autism Spectrum Disorders (ASDs) are childhood neurodevelopmental disorders with complex genetic origins. Previous studies have investigated the role of de novo Copy Number Variants (CNVs) and microRNAs as important but distinct etiological factors in ASD. We developed a novel computational procedure to assess the potential pathogenic role of microRNA genes overlapping de novo CNVs in ASD patients. Here we show that for chromosomes # 1, 2 and 22 the actual number of miRNA loci affected by de novo CNVs in patients was found significantly higher than that estimated by Monte Carlo simulation of random CNV events. Out of 24 miRNA genes over-represented in CNVs from these three chromosomes only …

Narcissistic Tendencies Among Actors

2014

Building on a two-dimensional reconceptualization of grandiose narcissism, we investigated how narcissistic admiration (the tendency toward agentic self-promotion) and rivalry (the tendency toward other derogation) are related to acting. Study 1 ( N = 583) showed that acting students scored higher on narcissistic admiration than students with other majors, but at the same time, the acting students scored lower on rivalry. In Study 2 ( N = 283), we compared improvisational theater actors with a comparison group and found the same pattern: Admiration was higher, but rivalry was lower among the actors (across both self-reports and informant reports). Effects persisted when we controlled for s…

Mirror neurons : physiological requirement for emotional empathy and social and moral behaviour of human and nonhuman primates

2018

Fil: Claramonte Sanz, Vicente. Universitat de València. Departament de Filosofia. Área de Lògica i Filosofia de la Ciència; España. Claramonte Sanz, V. (2018). Las neuronas espejo: presupuesto fisiológico de la empatía emocional y de las conductas sociales y morales en primates humanos y no humanos. Metatheoria, 8(2), 15-22. A partir de la evidencia científica y los análisis debidos a los estudios de investigadores como Rizzolatti, Sinigaglia, Galle-se, Goldman, Iacoboni, etc., este artículo argumenta que el vínculo entre neuronas espejo y empatía emocional resulta corroborado por los estudios de Neurociencia sobre la actividad perceptiva y las reacciones emocionales. En particular, con las…

The Potential Role of miRNAs in Cognitive Frailty.

2021

Frailty is an aging related condition, which has been defined as a state of enhanced vulnerability to stressors, leading to a limited capacity to meet homeostatic demands. Cognitive impairment is also frequent in older people, often accompanying frailty. Age is the main independent risk factor for both frailty and cognitive impairment, and compelling evidence suggests that similar age-associated mechanisms could underlie both clinical conditions. Accordingly, it has been suggested that frailty and cognitive impairment share common pathways, and some authors proposed “cognitive frailty” as a single complex phenotype. Nevertheless, so far, no clear common underlying pathways have been discove…

The function of mirror neurons in the learning process

2017

In the last years, Neurosciences have developed very much, being elaborated many important theories scientific research in the field. The main goal of neuroscience is to understand how groups of neurons interact to create the behavior. Neuroscientists studying the action of molecules, genes and cells. It also explores the complex interactions involved in motion perception, thoughts, emotions and learning. Brick fundamental nervous system is the nerve cell, neuron. Neurons exchange information by sending electrical signals and chemical through connections called synapses. Discovered by a group of Italian researchers from the University of Parma, neurons - mirror are a special class of nerve …

A multi-domain approach for smoothed particle hydrodynamics simulations of highly complex flows

2018

Abstract An efficient and accurate method is proposed to solve the incompressible flow momentum and continuity equations in computational domains partitioned into subdomains in the framework of the smoothed particle hydrodynamics method. The procedure does not require any overlap of the subdomains, which would result in the increase of the computational effort. Perfectly matching solutions are obtained at the surfaces separating neighboring blocks. The block interfaces can be both planar and curved surfaces allowing to easily decompose even geometrically complex domains. The smoothing length of the kernel function is maintained constant in each subdomain, while changing between blocks where…

Predicting perceived visual complexity of abstract patterns using computational measures: The influence of mirror symmetry on complexity perception

2017

Visual complexity is relevant for many areas ranging from improving usability of technical displays or websites up to understanding aesthetic experiences. Therefore, many attempts have been made to relate objective properties of images to perceived complexity in artworks and other images. It has been argued that visual complexity is a multidimensional construct mainly consisting of two dimensions: A quantitative dimension that increases complexity through number of elements, and a structural dimension representing order negatively related to complexity. The objective of this work is to study human perception of visual complexity utilizing two large independent sets of abstract patterns. A w…