Search results for "miR"
showing 10 items of 1117 documents
A High Throughput, Minimally Invasive, Ultrasound Guided Model for the Study of Catheter Associated Urinary Tract Infections and Device Encrustation …
2014
Purpose Catheter associated urinary tract infections are one of the most common health care associated infections. The condition is frequently complicated by encrustation, which blocks the catheter lumen. Preclinical research is limited by the lack of relevant high throughput and cost-effective animal models. Current models are restricted to female mice, associated with major transurethral loss of catheter materials during micturition, highly invasive and complex. We present an ultrasound guided, minimally invasive model that enables catheter associated urinary tract infection and catheter encrustation studies in each mouse gender. Materials and Methods Catheter segments (4 mm) were implant…
Lower Urinary Tract Symptoms: What's New in Medical Treatment?
2018
Abstract Context Pharmacological treatment is a cornerstone in the management of patients with lower urinary tract symptoms (LUTS). Objective To review emerging evidence in the medical treatment of LUTS. Evidence acquisition An Embase/Pubmed-based literature search was conducted in December 2017, screening for randomized controlled trials (RCTs), prospective and retrospective series, animal model studies, and reviews on medical treatment of LUTS. Evidence synthesis The main medical innovation in recent years in overactive bladder (OAB) has been the approval of the first β 3 -adrenoceptor agonists (mirabegron) and intradetrusor onabotulinum toxin A, while several other drugs such as antiepil…
Role of abdominal obesity for functional outcomes and complications in men treated with radical prostatectomy for prostate cancer: results of the Mul…
2014
Objective. This study aimed to evaluate the impact of abdominal obesity on preoperative features, complications and functional outcomes of men treated with radical prostatectomy (RP) for prostate cancer. Material and methods. In 2006 a multicentre Italian report on RP evaluated the surgical and functional characteristics of prostate cancer and RP outcomes. Age and waist circumference (WC) were recorded. Abdominal obesity was defined as a WC of at least 102 cm. International Index of Erectile Function (IIEF) score, prostate-specific antigen, prostate volume, tumour characteristics, presence/absence of perioperative complications and the number of blood units transfused were recorded. Preoper…
Predicting domain-specific actions in expert table tennis players activates the semantic brain network.
2018
Motor expertise acquired during long-term training in sports enables top athletes to predict the outcomes of domain-specific actions better than nonexperts do. However, whether expert players encode actions, in addition to the concrete sensorimotor level, also at a more abstract, conceptual level, remains unclear. The present study manipulated the congruence between body kinematics and the subsequent ball trajectory in videos of an expert player performing table tennis serves. By using functional magnetic resonance imaging, the brain activity was evaluated in expert and nonexpert table tennis players during their predictions on the fate of the ball trajectory in congruent versus incongruent…
Roles of the Core Components of the Mammalian miRISC in Chromatin Biology
2022
The Argonaute (AGO) and the Trinucleotide Repeat Containing 6 (TNRC6) family proteins are the core components of the mammalian microRNA-induced silencing complex (miRISC), the machinery that mediates microRNA function in the cytoplasm. The cytoplasmic miRISC-mediated post-transcriptional gene repression has been established as the canonical mechanism through which AGO and TNRC6 proteins operate. However, growing evidence points towards an additional mechanism through which AGO and TNRC6 regulate gene expression in the nucleus. While several mechanisms through which miRISC components function in the nucleus have been described, in this review we aim to summarize the major findings that have …
Mantošanas regulas piemērošana, vedot mantojuma lietu pie Latvijas notāra un ar to saistītie problēmjautājumi.
2020
Bakalaura darbā ir pētīta Eiropas Parlamenta un Padomes Regulas (ES) Nr. 650/2012 (2012. gada 4. jūlijs) par jurisdikciju, piemērojamiem tiesību aktiem, nolēmumu atzīšanu un izpildi un publisku aktu akceptēšanu un izpildi mantošanas lietās un par Eiropas mantošanas apliecības izveidi jeb Mantošanas regulas piemērošanas problemātika gadījumos, kad mantojuma lieta tiek vesta pie Latvijas notāra. Darba mērķis ir analizēt Mantošanas regulas būtiskākos jēdzienus, Mantošanas regulas atbilstību tās sākotnējiem mērķiem, kā arī izpētīt ar kādiem izaicinājumiem ir jāsaskaras Mantošanas regulas piemērotājiem Latvijā un sniegt atbilstošus risinājumus, lai atvieglotu Mantošanas regulas piemērošanu. Ņemo…
El conde de Buñol, en seruicio de la ... Duquesa del Infantado, escriuio estos milagros, principio de otros infinitos, hechos por la Madre de Dios y…
1601
Totes les p. orlades Sign.: [ ]2
Il tempo ritrovato di Masha e Orso
2015
L'articolo si colloca all'interno del lavoro di analisi dei cartoni animati rivolti alla prima infanzia nella loro dimensione intermediale.
Robot passes the mirror test by inner speech
2021
Abstract The mirror test is a well-known task in Robotics. The existing strategies are based on kinesthetic-visual matching techniques and manipulate perceptual and motion data. The proposed work attempts to demonstrate that it is possible to implement a robust robotic self-recognition method by the inner speech, i.e. the self-dialogue that enables reasoning on symbolic information. The robot self-talks and conceptually reasons on the symbolic forms of signals, and infers if the robot it sees in the mirror is itself or not. The idea is supported by the existing literature in psychology, where the importance of inner speech in self-reflection and self-concept emergence for solving the mirror…
Zvaigžņotā Debess: 2010, Rudens (209)
2010
Contents: G.Carevsky, I.Daube. Comet Bennett ; E.Fogels. Srinivasa Ramanujan ; M.Krastiņš. Smallest Planet of the Solar System: a Riddle of Centuries (1st part) ; A.Alksnis, Z.Alksne. Hot Jupiters and Their Retrograde Motion ; V.Karitāns. James Webb Space Telescope. What will it Be? ; K.Salmiņš. GFZ CHAMP Laser Tracking Award to SLR Station Riga ; J.Jansons. Vladimir Afanasjev, Officer of the Baikonur Cosmodrom in the 1970s (concluded) ; J.Limansky. International Year of Astronomy 2009 in Philately. Series EUROPA (2nd sequel) ; J.Dambītis. Centenary of Prominent Latvian Mathematician Ernests Fogels (1910-1985) ; J.Klētnieks. Sketches of History of Astronomy (concluded) ; M.Gills. Public Sun…