Search results for "miR"

EPA-0703 – Performance of the hamilton depression rating subscales to predict antidepressant treatment response in the early course of treatment

2014

Early improvement ( EI ), i.e. a symptom reduction from baseline of at least 20% after 2 weeks, has been proven to be a clinically useful predictor for later treatment outcome. In most studies EI is identified by using the sum score of the Hamilton Depression Rating Scale (HAMD). Several unidimensional subscales of the HAMD exist, which have proven to be an economic measure of treatment change. Their ability to detect onset of improvement in comparison to the full HAMD has not been researched yet. The present study investigated in patients with major depression (MD) (1) whether the HAMD subscales are a valid and economic option to predict antidepressant treatment response in the early cours…

Mirror imaging of impacted and supernumerary teeth in dizygotic twins: A case report

2015

Background: Mesiodens is the most common type of supernumerary tooth found in the premaxilla. It might be discovered during the clinical examination as a casual finding on a radiograph or as the cause of an unerupted maxillary central incisor. The genetic transmission of supernumerary and impacted teeth is poorly understood. Mirror imaging in twins has been reported frequently in relation to several unilateral dental anomalies including mesiodens. This phenomenon is the appearance of an asymmetrical feature or anomaly occurring on the right side of one twin but on the left side of the other twin. The event of mesiodens mirror imaging in monozygotic twins has been described in literature. Re…

Human Behavior in the Execution of Tasks: Influencing Factors of Decision-Making

2016

Making mistakes is part of general human behavior. This chapter gives an insight into the processes of the human brain and explains why and how we think and behave. Specific forms of human behavior are the reasons why specific methods of process management have developed.

Homeopathic remedies and mass advertising in Spain: 1880-1910

2020

La homeopatía se introdujo en España en la década de 1830, pero vivió su época dorada a finales del siglo XIX. Tradicionalmente se había dicho que la causa era la buena respuesta de los remedios homeopáticos frente a las epidemias de cólera que sobrevinieron en las décadas de 1880 y 1890. Aquí se demuestra que la publicidad de masas actuó a gran escala para legitimar los productos homeopáticos. En primer lugar, apareció la publicidad vinculada a empresas norteamericanas que pretendían abrir un mercado global. A continuación, fue una publicidad impulsada por farmacéuticos locales convertidos en fabricantes de producos homeopáticos. A través de estas dos fases, la publicidad de masas alteró l…

Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation

2015

Infectious agents develop intricate mechanisms to interact with host cell pathways and hijack their genetic and epigenetic machinery to change host cell phenotypic states. Among the Apicomplexa phylum of obligate intracellular parasites, which cause veterinary and human diseases, Theileria is the only genus that transforms its mammalian host cells. Theileria infection of bovine leukocytes induces proliferative and invasive phenotypes associated with activated signalling pathways, notably JNK and AP-1 (ref. 2). The transformed phenotypes are reversed by treatment with the theilericidal drug buparvaquone. We used comparative genomics to identify a homologue of the peptidyl-prolyl isomerase PI…

New data to distribution of ferns in Tajikistan (Middle Asia)

2016

The paper presents new chorological data of eleven fern species (Ophioglossum bucharicum, Azolla filiculoides, Botrychium lunaria, Gymnocarpium robertianum, Cryptogramma stelleri, Polystichum aculeatum, Asplenium trichomanes, Asplenium viride, Asplenium ruta-muraria, Adiantum capillus-veneris and Salvinia natans) in central Pamir Alai Mts in Tajikistan. Except Azolla filiculoides all of them are native to the flora of Tajikistan. The dry and warm climate in lowlands and middle mountains as well as harsh conditions in higher elevation of Pamir are not suitable for Pteridophytes. Thus, many of fern species are rare in Tajikistan, having less than five locations. List of localities of the spec…

The analysis of urban travellers’ latent preferences to explain their mode choice behaviour

2012

Our research aims to explore the impact of latent variables, mirroring urban travellers’ attitudes and perceptions, on the individual decision making process regarding the mode of transport. The paper describes the first results of an ongoing research activity, which derive from a pilot study conducted in Palermo, the capital of the Sicilian Region (in the south of Italy), and demonstrate that policy makers, in designing a socially desirable and environmentally sustainable urban mobility system, should take into account how travellers perceive the qualitative dimensions of transport.

P2.01-017 Circulating miRNAs in Lung Cancer Are Associated to Pro-Tumorigenic and Immunosuppressive Microenvironment

2017

Zvaigžņotā Debess: 2011/12, Ziema (214)

2011

Saturs: Gamma staru astronomijas problēmas ; Apollo-14 Mēness ekspedīcija ; A.Laure. Protoplanetāro miglāju stadija zvaigžņu evolūcijā ; A.A. Jaunumi īsumā: Oglekļa zvaigzne un rentgenstaru avots ; A.Alksnis. Heršels ielūkojas Miras galvā ; D.Docenko. Jauns dziļš debess apskats WiggleZ ir pabeigts: gaidām rezultātus ; A.A. Jaunumi īsumā: Pundurplanēta Erīda ir precīzi izmērīta. Atvērto durvju dienā Garhingā... ; M.Gertāns. Iepazīstot Kenedija kosmosa centru un atvadoties no Space Shuttle ; J.Dambītis. Ievērojams Latvijas matemātiķis – docents Nikolajs Brāzma (1913-1966) ; J.Jansons. Fiziķu centieni 1950.-1960. gados atgriezt fundamentālo zinātni Universitātē ; V.Fļorovs, A.Cēbers, D.Bočarov…

A closer look at mirrors and quotients of Calabi-Yau threefolds

2016

Let X be the toric variety (P1)4 associated with its four-dimensional polytope 1. Denote by X˜ the resolution of the singular Fano variety Xo associated with the dual polytope 1o. Generically, anticanonical sections Y of X and anticanonical sections Y˜ of X˜ are mirror partners in the sense of Batyrev. Our main result is the following: the Hodge-theoretic mirror of the quotient Z associated to a maximal admissible pair (Y, G) in X is not a quotient Z˜ associated to an admissible pair in X˜ . Nevertheless, it is possible to construct a mirror orbifold for Z by means of a quotient of a suitable Y˜. Its crepant resolution is a Calabi-Yau threefold with Hodge numbers (8, 4). Instead, if we star…