Search results for "microbiology"

showing 10 items of 7546 documents

Enhancing heterologous protein expression and secretion in HEK293 cells by means of combination of CMV promoter and IFNα2 signal peptide

2016

Efficient production and secretion of recombinant proteins in mammalian cell lines relies in a combination of genetic, metabolic and culture strategy factors. The present work assesses the influence of two key genetic components of expression vectors (promoter and signal peptide) on protein production and secretion effciency in HEK293 cells expressing eGFP as a reporter protein. Firstly, the strength of 3 different promoters was evaluated using transient expression methods. Flow cytometry analysis revealed that the highest level of intracellular protein expression was found when eGFP was under the control of CMV promoter, being 3-times higher in comparison to the rest of the promoters teste…

0106 biological sciences0301 basic medicineSignal peptideGreen Fluorescent ProteinsCytomegalovirusHeterologousBioengineeringProtein Sorting SignalsBiology01 natural sciencesApplied Microbiology and BiotechnologyGreen fluorescent protein03 medical and health sciences010608 biotechnologyProtein biosynthesisHumansSecretionPromoter Regions GeneticExpression vectorInterferon-alphaPromoterGeneral MedicineMolecular biologyRecombinant ProteinsHEK293 Cells030104 developmental biologyCell cultureBiotechnologyJournal of Biotechnology
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Selection of indigenous yeast strains for the production of sparkling wines from native Apulian grape varieties.

2018

We report the first polyphasic characterization of native Saccharomyces cerevisiae in order to select candidate strains for the design of starter cultures tailored for Apulian sparkling wines obtained from local grape variety. In addition, it is the first survey in our region that propose the selection of autochthonous starter cultures for sparkling wine i) including a preliminary tailored genotypic and technological screening, and ii) monitoring analytical contribution during secondary fermentation in terms of volatile compounds (VOCs). Furthermore, we exploit the potential contribute of autochthonous cultures throughout the productive chain, including the possible improvement of base wine…

0106 biological sciences0301 basic medicineSparkling wine production030106 microbiologyWineSaccharomyces cerevisiaeAutochthonous grape varietiesrr01 natural sciencesMicrobiologyInterdelta03 medical and health sciencesStarterSparkling wine010608 biotechnologyVitisFood scienceSelection (genetic algorithm)Fermentation in winemakingWineindigenous yeastsbiologyautochthonous starter culturesfood and beveragesGeneral Medicinebiology.organism_classificationggYeastFermentationFood MicrobiologyFermentationFood ScienceBiotechnologyInternational journal of food microbiology
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Oxygen Availability during Growth Modulates the Phytochemical Profile and the Chemo-Protective Properties of Spinach Juice.

2018

Fruits and vegetables are a good source of potentially biologically active compounds. Their regular consumption in the human diet can help reduce the risk of developing chronic diseases such as cardiovascular diseases and cancer. Plants produce additional chemical substances when subject to abiotic stress or infected by microorganisms. The phytochemical profile of spinach leaves (Spinacia oleracea L.), which is a vegetable with widely recognized health-promoting activity, has been affected by applying root hypoxic and re-oxygenation stress during plant growth. Leaf juice at different sampling times has been subject to liquid chromatography mass spectrometry (LC-MSn) analysis and tested on t…

0106 biological sciences0301 basic medicineSpinaciaAntioxidantHT29 cell lineCell Survivalmedicine.medical_treatmentLiquid Chromatography-Mass Spectrometry<i>Spinacia oleracea</i> L.lcsh:QR1-502antioxidant activitySpinacia oleracea L.Anti-proliferative activity; Antioxidant activity; Comet Assay; HT29 cell line; Liquid Chromatography-Mass Spectrometry; Spinacia oleracea L;medicine.disease_cause01 natural sciencesBiochemistrylcsh:MicrobiologyAntioxidantsMass SpectrometryArticle03 medical and health sciencesSpinacia oleraceamedicineHumansFood scienceMolecular BiologyCell ProliferationbiologyAbiotic stressChemistryChemistry PhysicalPlant Extractsfood and beveragesBiological activitybiology.organism_classificationAntineoplastic Agents PhytogenicComet assayFruit and Vegetable JuicesOxygen030104 developmental biologyPhytochemicalSpinachanti-proliferative activityComet AssayDrug Screening Assays AntitumorHT29 CellsOxidative stress010606 plant biology & botanyChromatography LiquidBiomolecules
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Energy intake functions and energy budgets of ectotherms and endotherms derived from their ontogenetic growth in body mass and timing of sexual matur…

2017

Abstract Ectothermic and endothermic vertebrates differ not only in their source of body temperature (environment vs. metabolism), but also in growth patterns, in timing of sexual maturation within life, and energy intake functions. Here, we present a mathematical model applicable to ectothermic and endothermic vertebrates. It is designed to test whether differences in the timing of sexual maturation within an animal's life (age at which sexual maturity is reached vs. longevity) together with its ontogenetic gain in body mass (growth curve) can predict the energy intake throughout the animal's life (food intake curve) and can explain differences in energy partitioning (between growth, repro…

0106 biological sciences0301 basic medicineStatistics and ProbabilityOntogenymedia_common.quotation_subjectZoologyGrowth010603 evolutionary biology01 natural sciencesEndothermic processGeneral Biochemistry Genetics and Molecular BiologyBody Mass IndexBody Temperature03 medical and health sciencesbiology.animalAnimalsSexual maturitySexual Maturationmedia_commonGeneral Immunology and MicrobiologybiologyApplied MathematicsLongevityVertebrateThermogenesisGeneral MedicineGrowth curve (biology)Models Theoretical030104 developmental biologyModeling and SimulationEctothermVertebratesReproductionEnergy IntakeGeneral Agricultural and Biological SciencesJournal of Theoretical Biology
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Spoilage potential of Brettanomyces bruxellensis strains isolated from Italian wines

2018

Abstract Brettanomyces bruxellensis is an important wine spoilage agent. In this study a population of Brettanomyces strains isolated from Italian wines was thoroughly investigated to evaluate adaptability to wine conditions and spoilage potential. The presumptive isolates of Brettanomyces were identified at species level with 26S rRNA gene sequencing and species-specific PCR, and subsequently subjected to analysis of intra-species variability through the study of intron splice sites (ISS-PCR). Although, some strains were tracked in wines from different regions, extensive genetic biodiversity was observed within the B. bruxellensis population investigated. All strains were evaluated for the…

0106 biological sciences0301 basic medicineStrain resistanceGenotypeBrettanomyces030106 microbiologyPopulationFood spoilageBrettanomyces bruxellensisBrettanomycesVolatile phenolsWineWine spoilageMicrobial contaminationRibotyping01 natural sciences03 medical and health sciencesVolatile phenolPhenolsSpecies level010608 biotechnologyBrettanomyceFood scienceDNA FungaleducationYeast physiologyPhylogenyWineVolatile Organic Compoundseducation.field_of_studyGenetic diversitybiologydigestive oral and skin physiologyfood and beveragesbiology.organism_classificationItalySettore AGR/16 - MICROBIOLOGIA AGRARIAFood MicrobiologyFood Science
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Production of extracellular fructans by Gluconobacter nephelii P1464.

2015

UNLABELLED Bacterial extracellular fructans, known as levans, have potential applications in food, pharmaceutical and cosmetic industries and high fructan producing strains could contribute into the cost reduction and more extensive commercial usage of them. An acetic acid bacteria (AAB) isolate P1464 was obtained from the Microbial Strain Collection of Institute of Microbiology and Biotechnology, University of Latvia and identified as Gluconobacter nephelii by DNA-DNA hybridization and the formation of extracellular fructans by this strain was confirmed. Isolated extracellular fructose polymers were characterized using FT-IR spectroscopy and the structural features of fructan appeared as s…

0106 biological sciences0301 basic medicineSucroseGluconobactermedicine.medical_treatment030106 microbiologyGluconobacterFructose01 natural sciencesApplied Microbiology and BiotechnologyZymomonas mobilis03 medical and health scienceschemistry.chemical_compoundFructanBioreactors010608 biotechnologySpectroscopy Fourier Transform InfraredExtracellularmedicineAcetic acid bacteriaAcetic AcidbiologyPrebioticPolysaccharides BacterialFructosebiology.organism_classificationDNA FingerprintingFructansMolecular WeightchemistryBiochemistryLetters in applied microbiology
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Opinions 97, 98 and 99

2020

The International Committee on Systematics of Prokaryotes has formally endorsed the conclusions of the Judicial Commission on three pending Requests for an Opinion, thereby allowing the corresponding Opinions to be issued. According to Opinion 97, the request for the conservation of the name Streptomyces scabies is denied, allowing the continued use of the correction Streptomyces scabiei . Opinions 98 and 99 conclude that in the absence of associated authentic type material, the names Bacillus aeolius and Pectinatus portalensis , respectively, are not validly published.

0106 biological sciences0301 basic medicineSystematicsGeneral MedicineBiologyStreptomyces scabiesbiology.organism_classification010603 evolutionary biology01 natural sciencesMicrobiologyStreptomyces03 medical and health sciencesBacillus aeolius030104 developmental biologyType (biology)LawPectinatus portalensisEcology Evolution Behavior and SystematicsInternational Journal of Systematic and Evolutionary Microbiology
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Influence of salt of different origin on the microbiological characteristics, histamine generation and volatile profile of salted anchovies (Engrauli…

2018

Abstract The effect of six salts of different geographical areas on the quality of salted anchovies was evaluated. The crude salts were chemically characterized by determination of inorganic and volatile organic compounds (VOCs). Salted anchovies, corresponding to six experimental trials, were subjected to microbiological, chemical (including histamine content) and sensory analysis during the entire period of ripening (150 days). The salts were characterized by marked differences in terms of major cations and trace element amounts. Among the 27 VOCs detected, octadecane was the most abundant compound and the main differences of the salts were registered for alkanes and alcohols. During matu…

0106 biological sciences0301 basic medicineTasteSaltSettore AGR/13 - Chimica Agraria030106 microbiologySalt (chemistry)01 natural sciencesSensory analysis03 medical and health scienceschemistry.chemical_compoundEngraulis010608 biotechnologyAnchovieFood scienceSettore BIO/06 - Anatomia Comparata E CitologiaStaphylococcaceaechemistry.chemical_classificationbiologyChemistryVOCRipeningbiology.organism_classificationLactic acidComposition (visual arts)Bacterial communityHistamineSettore AGR/16 - Microbiologia AgrariaFood ScienceBiotechnologyFood Control
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UV-screening and springtime recovery of photosynthetic capacity in leaves of Vaccinium vitis-idaea above and below the snow pack

2019

International audience; Evergreen plants in boreal biomes undergo seasonal hardening and dehardening adjusting their photosynthetic capacity and photoprotection; acclimating to seasonal changes in temperature and irradiance. Leaf epidermal ultraviolet (UV)-screening by flavonols responds to solar radiation, perceived in part through increased ultraviolet-B (UV-B) radiation, and is a candidate trait to provide cross-photoprotection. At Hyytiälä Forestry Station, central Finland, we examined whether the accumulation of flavonols was higher in leaves of Vaccinium vitis-idaea L. growing above the snowpack compared with those below the snowpack. We found that leaves exposed to colder temperature…

0106 biological sciences0301 basic medicineTime FactorsPhotoinhibitionBOREALPhysiologyPlant ScienceForests01 natural sciencesPlant EpidermisAnthocyaninsSoilFlavonolsLOW-TEMPERATURESnowPhotosynthesis1183 Plant biology microbiology virologychemistry.chemical_classificationspring dehardening.CLIMATE-CHANGEbiologyChemistryTemperatureUnderstoreyHorticultureLIGHTSeasonsVacciniumUltraviolet RaysGrowing seasonPhotosynthesisDWARF SHRUB03 medical and health sciencesLEAFPHOTOSYSTEM-IIGenetics[SDV.BV]Life Sciences [q-bio]/Vegetal BiologyVaccinium vitis-idaeaFlavonoidsSpring dehardeningPhotoprotectionSpectral qualityPhotosystem II Protein ComplexPigments Biological15. Life on landEvergreenbiology.organism_classificationPhotosynthetic capacitySUB-ARCTIC HEATHPlant Leaves030104 developmental biology13. Climate actionPhotoprotectionWINTERB RADIATIONArctic browning010606 plant biology & botany
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Testing the enemy release hypothesis: abundance and distribution patterns of helminth communities in grey mullets (Teleostei: Mugilidae) reveal the s…

2017

International audience; The abundance and aggregation patterns of helminth communities of two grey mullet hosts, Liza haematocheilus and Mugil cephalus, were studied across 14 localities in Atlantic and Pacific marine areas. The analysis matched parasite communities of (i) L. haematocheilus across its native and introduced populations (Sea of Japan and Sea of Azov, respectively) and (ii) the introduced population of L. haematocheilus with native populations of M. cephalus (Mediterranean, Azov-Black and Japan Seas). The total mean abundance (TMA), as a feature of the infection level in helminth communities, and slope b of the Taylor’s power law, as a measure of parasite aggregation at the in…

0106 biological sciences0301 basic medicineTotal mean abundancePopulationSpecies distributionIntroduced species010603 evolutionary biology01 natural sciencesHost SpecificityInvasive speciesFish Diseases03 medical and health sciencesSpecies SpecificityAbundance (ecology)AnimalsHelminths[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/Parasitology14. Life underwatereducationeducation.field_of_studybiologyMugil cephalusEcologyMugilHost (biology)030108 mycology & parasitologybiology.organism_classificationTaylor’s lawSmegmamorphaInfectious DiseasesSpecies abundance distributionParasitologyLiza haematocheilusHelminthiasis AnimalIntroduced SpeciesAnimal Distribution
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