Search results for "middle-age"
showing 8 items of 28 documents
Clinical and Morphologic Predictors of Outcome in a Multicenter Cohort of ITP Patients Treated with Trombopoietin Analogues
2018
Abstract Background: The role of bone marrow response in patients with immune thrombocytopenia (ITP) has gained paramount importance since the last 10 years, with the demonstrations that marrow megakaryocytes (MGK) are unable to properly compensate platelets peripheral destruction. TPO receptor agonists (TPOa), namely romiplostim (ROMI) and eltrombopag (EPAG), by stimulating megakaryopoiesis are able to induce a response in 74% to 94% of cases in clinical trials. However, real world use of these drugs has shown frequent changes in individual dose requirement, the possibility of treatment discontinuation, and their effectiveness outside registered indications; moreover, nothing is known abou…
Taisteluiden kuvaus Eerikinkronikassa : sukupuolihistoriallinen näkökulma hyvään soturiuteen keskiajalla
2018
Kandidaatintutkielma taisteluista Eerikinkronikassa, johon sisältyy siinä esiintyvän soturiuden tutkiminen sukupuolihistorian näkökulmassa (maskuliinisuuden tutkimus).
Associations of physical performance and physical activity with mental well-being in middle-aged women
2021
Abstract Background To investigate whether physical performance is independently of physical activity (PA) associated with positive and negative dimensions of mental well-being in middle-aged women. Methods Data were drawn from the Estrogenic Regulation of Muscle Apoptosis (ERMA) study in which women 47 to 55 years were randomly selected from the Finnish National Registry. They (n = 909) participated in measurements of physical performance (handgrip force, knee extension force, vertical jumping height, maximal walking speed, and six-minute walking distance). Both mental well-being (the Centre for Epidemiologic Studies Depression Scale, the International Positive and Negative Affect Schedule…
Ageing and consumption in Finland : the effect of age and life course stage on ecological, economical and self-indulgent consumption among late middl…
2017
Previous studies on ageing consumers have mainly focused on chronological age and generational values or studied ageing and consumption with cross-sectional data. Few quantitative studies exist that examine the effect of age together with life course on consumption using longitudinal data. To bridge this gap, the article examines ageing and attitudes towards consumption in Finland, focusing particularly on late middle-agers (46–60 year-olds) in comparison with young adults (18–30 year-olds) between 1999 and 2014. The article explores three consumption patterns based on attitudinal statements: ecological, economical and self-indulgent consumption. Through analysis of a nationally representat…
Elämänarvot keski-iässä : psykometrinen rakenne ja yhteydet persoonallisuuden piirteisiin ja psyykkiseen hyvinvointiin
2016
This study examined, first, basic human values’ and life goals’ factor structures and the reciprocal links between these measures; second, the connections between personality traits and values, and possible gender differences in these relations; and third, the relations between life goals and mental well-being, and whether life goals act as mediators in the associations between personality traits and mental well-being. The participants were drawn from the Jyväskylä Longitudinal Study of Personality and Social Development (JYLS). Data used here were collected at ages 42 and 50 (n = 212–242). The results yielded a 14- factor value structure (societal concern, tolerance, protecting nature, car…
Female reproductive factors are associated with objectively measured physical activity in middle-aged women
2017
Physical activity improves health and may delay the onset of several chronic diseases. For women in particular, the rate of these diseases accelerates at middle age; therefore it is important to identify the determinants of health-enhancing physical activity during midlife in this population. In this study, we focused on determinants that are unique to the female sex, such as childbearing and menopause. The main objective was to characterize the level of physical activity and differences between active and inactive middle-aged Finnish women. In addition, we examined the association of physical activity with female reproductive factors at midlife. The study population consisted of 647 women …
Bem-estar psicológico em função da etapa de vida, sexo e sua interação
2016
Objetivo. Evaluar las diferencias en las dimensiones del bienestar psicológico en función de los grupos de edad, sexo y su interacción. Método. Se obtuvo una muestra de 706 participantes, dividida en tres grupos de edad (jóvenes, adultos y adultos mayores), quienes respondieron a las escalas de bienestar psicológico de Ryff. Se calculó un Manova teniendo en cuenta las variables grupo de edad, sexo y su interacción. Posteriormente, se realizaron varios Anova para conocer entre cuáles grupos existían diferencias para cada dimensión. Resultados. El análisis mostró una disminución, con la edad, en las dimensiones de bienestar psicológico de relaciones positivas con otros y crecimiento personal,…
Impact of using different levels of threshold-based artefact correction on the quantification of heart rate variability in three independent human co…
2020
Heart rate variability (HRV) is a non-invasive indicator of autonomic nervous system function. HRV recordings show artefacts due to technical and/or biological issues. The Kubios software is one of the most used software to process HRV recordings, offering different levels of threshold-based artefact correction (i.e., Kubios filters). The aim of the study was to analyze the impact of different Kubios filters on the quantification of HRV derived parameters from short-term recordings in three independent human cohorts. A total of 312 participants were included: 107 children with overweight/obesity (10.0 ±