Search results for "mikrorakenne"
showing 4 items of 4 documents
Three-dimensional analysis of tumour vascular corrosion casts using stereoimaging and micro-computed tomography
2009
Objective: In order to perform effective translational research for cancer therapy, we need to employ preclinical models which reflect the clinical situation. The purpose of this study was to quantitatively compare the vascular architecture of human colorectal cancer and experimental tumour models to determine the suitability of animal models for vascular studies and antivascular therapy.Methods: In this study we investigated the three-dimensional properties of colonic tumour vasculature in both human clinical tissues (normal mucosa control [n = 20], carcinoma [n = 20] and adenoma In = 61) and murine colorectal xenografts (LS147T [n = 6] and SW1222 [n = 6]). Scanning Electron Microscope Ste…
Morphological analysis of human cortical bone using high-resolution X-ray microtomography
2012
Structural and elastic properties of bone are related to microstructural parameters such as porosity and anisotropy. Microtomography (μCT) enables assessment of bone microstructural geometry, typically down to a voxel size of 5 microns. The purpose of this thesis was to evaluate whether using a higher (sub-micrometer) voxel resolution in X-ray μCT enables detection of new, finer, details in human cortical bone. The second objective was to measure several morphological parameters that determine the microstructure, and to compare two different microtomographs. To this end, twenty four human cadaveric femur samples were imaged by Xradia XCT-400 at a voxel size of 0.56 - 0.59 μm and spatial res…
Crystalline wax coverage of the imaginal cuticule in Calopteryx splendens (Odonata: Calopterygidae)
2009
In this study we use high resolution SEM to describe the diversity of wax crystals and their distribution on different morphological structures in male individuals of Calopteryx splendens. The entire cuticle surface of this damselfly, with the exception of ommatidia and ocelli, is covered with crystalline wax in dimensions from submicron to micron range. It is shown that shape – rod-like, plate like, filamentous, etc. –, size, and density of crystals vary on different surfaces and in individuals of different ages. Additionally, we demonstrate different types of damage to the crystalline wax layer: scratches, compressions, wear, and contamination. The primary function of the wax crystalline …