Search results for "mikrotomografia"
showing 3 items of 3 documents
Three-dimensional analysis of tumour vascular corrosion casts using stereoimaging and micro-computed tomography
2009
Objective: In order to perform effective translational research for cancer therapy, we need to employ preclinical models which reflect the clinical situation. The purpose of this study was to quantitatively compare the vascular architecture of human colorectal cancer and experimental tumour models to determine the suitability of animal models for vascular studies and antivascular therapy.Methods: In this study we investigated the three-dimensional properties of colonic tumour vasculature in both human clinical tissues (normal mucosa control [n = 20], carcinoma [n = 20] and adenoma In = 61) and murine colorectal xenografts (LS147T [n = 6] and SW1222 [n = 6]). Scanning Electron Microscope Ste…
Analysis of fluid flow through porous media based on x-ray micro-tomographic reconstructions
2010
This thesis deals with creeping fluid flow through fibrous porous materials. Permeability through a porous medium is a measure of the ability of the material to transmit fluids. For testing and demonstration purposes the permeability values of a few fibrous heterogeneous materials, namely synthetic non-woven felt, wet pressing felt, cardboard, newsprint and hardwood paper, were measured experimentally. Reconstructions of the same materials under similar compression states were captured by x-ray micro-tomography. The actual microscopic pore structure thus obtained was utilised in the numerical lattice-Boltzmann analysis for solving the fluid flow permeability of the materials. Agreement betw…
Morphological analysis of human cortical bone using high-resolution X-ray microtomography
2012
Structural and elastic properties of bone are related to microstructural parameters such as porosity and anisotropy. Microtomography (μCT) enables assessment of bone microstructural geometry, typically down to a voxel size of 5 microns. The purpose of this thesis was to evaluate whether using a higher (sub-micrometer) voxel resolution in X-ray μCT enables detection of new, finer, details in human cortical bone. The second objective was to measure several morphological parameters that determine the microstructure, and to compare two different microtomographs. To this end, twenty four human cadaveric femur samples were imaged by Xradia XCT-400 at a voxel size of 0.56 - 0.59 μm and spatial res…