Search results for "mixture"

showing 10 items of 1178 documents

Activation of bee venom phospholipase A2 through a peptide-enzyme complex

1995

AbstractPhospholipase A2 activation by membrane-bound peptides was investigated in order to understand the role of the membrane-induced conformation on activation, and to examine the occurrence of a peptide-enzyme complex at the lipid/water interface. For the peptides studies, bee venom phospholipase A2 was stimulated regardless of the membrane-bound conformation (α-helix, β-sheet or random coil). Using antisera raised against melittin, we were able to demonstrate the occurrence of a calcium-dependent complex involving the enzyme, phospholipid substrate, and peptide.

Enzyme complexProtein ConformationMolecular Sequence DataBiophysicsPhospholipidPeptidePhospholipaseBiochemistrycomplex mixturesAbellesMelittinAntibodiesPhospholipases AProtein Structure Secondarychemistry.chemical_compoundEnzyme activatorPhospholipase A2Structural BiologyGeneticsAnimalsAmino Acid SequencePhospholipaseMolecular BiologyPeptide sequencePeptide-enzyme complexchemistry.chemical_classificationbiologyCircular DichroismMembrane ProteinsMelittinCell BiologyMelittenEnzyme ActivationBee VenomsPhospholipases A2chemistryBiochemistryLiposomesbiology.proteinPèptidsPeptides
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Robust dynamic comfort modeling for motorcycle riding

2015

Comfort modeling is considered a prerequisite in motorcycle design, primarily to address safety concerns and to position the product on the market. However, a comprehensive methodology for comfort modeling during the earliest development phases of a motorcycle model is still missing. Anthropometrical variation is the main noise factor to consider in comfort modeling in relation to the unavoidable variability of body segments. However, comfort is a subjective concept influencing riders' choice of motorcycle model. This work is a generalization of the robust ergonomic design methodology aimed at designing products whose ergonomic performance is insensitive to anthropometrical variation. This …

ErgonomicHuman modelingMan-machine interactionSettore SECS-S/02 - Statistica Per La Ricerca Sperimentale E TecnologicaMixture noise factor distributionRobust designMotorcycle designComfort assessmentHuman Factors and ErgonomicSettore ING-IND/16 - Tecnologie E Sistemi Di LavorazioneDigital mock-upIndustrial and Manufacturing Engineering
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Robust dynamic comfort modelling for motorcycle riding

2015

Comfort modeling is considered a prerequisite in motorcycle design, primarily to address safety concerns and to position the product on themarket. However, a comprehensive methodology for comfort modeling during the earliest development phases of a motorcycle model is still missing. Anthropometrical variation is the main noise factor to consider in comfort modeling in relation to the unavoidable variability of body segments. However, comfort is a subjective concept influencing riders’ choice of motorcycle model. This work is a generalization of the robust ergonomic design methodology aimed at designing products whose ergonomic performance is insensitive to anthropometrical variation. This w…

ErgonomicMan–machine interactionHuman modelingSettore SECS-S/02 - Statistica Per La Ricerca Sperimentale E TecnologicaRobust designMixture noise factor distributionMotorcycle designComfort assessmentDigital mock-up
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Labor productivity and firm-level TFP with technology-specific production functions

2020

Abstract We investigate the technological dimension of productivity, presenting an empirical methodology based on mixture models to disentangle the labor productivity differences associated with the firm's choice of technology (BTFP) and those related to the firm's ability to exploit the adopted technology (WTFP). The estimation endogenously determines the number of technologies (in the sector) and degree of technology sharing across firms (i.e., for each firm, the probability of using a given technology). By using comparable data for about 35,000 firms worldwide distributed across 22 (two-digit) sectors, we show BTFP to be at least as important as WTFP in explaining the labor productivity …

EstimationEconomics and EconometricsSimultaneityExploit05 social sciencesTFPTFP; Technology adoption; Production function estimation; Mixture modelsProduction function estimation0502 economics and businessEconomicsProduction (economics)Statistical dispersion050207 economicsMixture modelsTotal factor productivityProductivityIndustrial organization050205 econometrics Technology adoption
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Latent segmentation in business-to-business based on information and communication technology and relationship variables

2016

Our work is focused on the segmentation analysis in the Spanish tourist industry. Using a sample of travel agencies who evaluated the relationship with their main supplier (relationship value, relationship benefits and perceived information and communication technologies (ICTs) use), we attempt to examine the utility of these variables as specific and subjective segmentation criteria for identifying heterogeneous groups. The estimation of a finite mixture model suggests that these bases are able to discriminate firms into six latent classes with different levels of ICT use and relationship variables. The novelty in this work lies in the application of latent segmentation methodology and th…

EstimationKnowledge managementComputer sciencebusiness.industry05 social sciencesGeography Planning and DevelopmentNoveltySample (statistics)Business-to-businessMixture modelInformation and Communications TechnologyTourism Leisure and Hospitality Management0502 economics and business050211 marketingSegmentationMarketingbusiness050212 sport leisure & tourismTourismTourism Economics
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Combined effects of compost and Medicago sativa in recovery a PCB contaminated soil

2020

The effectiveness of adding compost and the plant Medicago sativa in improving the quality of a soil historically contaminated by polychlorinated biphenyls (PCBs) was tested in greenhouse microcosms. Plant pots, containing soil samples from an area contaminated by PCBs, were treated with the compost and the plant, separately or together. Moreover, un-treated and un-planted microcosms were used as controls. At fixed times (1, 133 and 224 days), PCBs were analysed and the structure (cell abundance, phylogenetic characterization) and functioning (cell viability, dehydrogenase activity) of the natural microbial community were also measured. The results showed the effectiveness of the compost an…

FISH methodlcsh:Hydraulic engineeringSoil testplant-assisted bioremediationGeography Planning and Developmentmicrobial functioningpersistent organic pollutants010501 environmental sciencesAquatic Scienceengineering.material01 natural sciencesBiochemistrycomplex mixtures03 medical and health scienceslcsh:Water supply for domestic and industrial purposesFISHlcsh:TC1-978microbial functionELFAMedicago sativaPersistent organic pollutant030304 developmental biology0105 earth and related environmental sciencesWater Science and Technology0303 health scienceslcsh:TD201-500biologyCompostChemistrymicrobial structurefungifood and beveragesContaminationbiology.organism_classificationSoil contaminationplant-assisted bioremediation;persistent organic polluttantsHorticultureMicrobial population biologyengineeringMicrocosmBacteriafish methods
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Modeling temporal treatment effects with zero inflated semi-parametric regression models: The case of local development policies in France

2017

International audience; A semi-parametric approach is proposed to estimate the variation along time of the effects of two distinct public policies that were devoted to boost rural development in France over a similar period of time. At a micro data level, it is often observed that the dependent variable, such as local employment, does not vary along time, so that we face a kind of zero inflated phenomenon that cannot be dealt with a continuous response model. We introduce a conditional mixture model which combines a mass at zero and a continuous response. The suggested zero inflated semi-parametric statistical approach relies on the flexibility and modularity of additive models with the abi…

FOS: Computer and information sciencesEconomics and EconometricsLocal Developmentsemiparametric regressiondifferencePublic policyselection01 natural sciencesStatistics - Applicationslocal developmentpanel data010104 statistics & probabilityEconomica0502 economics and businessEconometricsApplications (stat.AP)0101 mathematics[MATH]Mathematics [math]Additive modelsemi-parametric regressionenterprise zonespropensity scoreJEL Classification: C14 C23 C54 O18050205 econometrics Mathematicsinferencesmoothing parametertemporal effects05 social sciencesSH1_2SH1_6multiple treatmentspolicy evaluation[SHS.ECO]Humanities and Social Sciences/Economics and FinanceZero (linguistics)Rural developmentVariation (linguistics)asymptoticsmixture of distributionsSemi parametric regressionAdditive modelsPanel dataAdditive models; local development; mixture of distributions; multiple treatments; panel data; policy evaluation; semiparametric regression; temporal effects
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Happy Spouses, Happy Parents? Family Relationships Among Finnish and Dutch Dual Earners

2010

Contains fulltext : 90432.pdf (Publisher’s version ) (Closed access) In this study links between spousal and parent-child relationships among Finnish (n = 157 couples) and Dutch (n = 276 couples) dual earners with young children were examined using paired questionnaire data. Variable-oriented analyses (structural equation modeling with a multigroup procedure) supported the spillover hypothesis, as higher levels of satisfaction in the spousal relationship were related to higher quality in the parent-child relationship and lower parental role restrictions. These connections did not differ by gender or country. With family typological analyses (mixture modeling), 4 family types were identified…

Family relationshipArts and Humanities (miscellaneous)Quality of lifeMarital satisfactionAnthropologyCross-culturalMixture modelingPsychologyDevelopmental PsychopathologySocial Sciences (miscellaneous)Questionnaire dataStructural equation modelingDevelopmental psychologyJournal of Marriage and the Family
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Classification of spatio-temporal point pattern in the presence of clutter using K-th nearest neighbour distances

2019

In a point process spatio-temporal framework, we consider the problem of features detection in the presence of clutters. We extend the methodology of Byers and Raftery (1998) to the spatio-temporal context by considering the properties of the K-th nearest-neighbour distances. We make use of the spatio-temporal distance based on the Euclidean norm where the temporal term is properly weighted. We show the form of the probability distributions of such K-th nearest-neighbour distance. A mixture distribution, whose parameters are estimated with an EM algorithm, is used to classify points into clutters or features. We assess the performance of the proposed approach with a simulation study, togeth…

FeatureSpatio-temporal point patterns.EarthquakeClutterMixtureEM algorithmNearestneighbour distanceSettore SECS-S/01 - Statistica
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Trajectories of life satisfaction and the financial situation in the transition to adulthood

2013

The aims of this study were (1) to investigate  young adults’ life satisfaction changes during the transition to adulthood, (2) to identify possible life satisfaction developmental trajectories during the transition, and (3) to examine how individuals’ agency and personal financial situations are related to the identified life satisfaction trajectories in the contexts of life-span and life course theories of development. The present study is part of the longitudinal Finnish Educational Transitions (FinEdu) study, in which a total of 372 (278 female and 94 male) young adults filled in questionnaires at four measurement points, that is, twice before (at 18 and 19 years of age) and twice after…

FinanceLongitudinal studyHigher educationbusiness.industry4. EducationTransition (fiction)05 social sciencesLife satisfaction050109 social psychologyDevelopmental psychology8. Economic growthAgency (sociology)Life course approachMixture modelling0501 psychology and cognitive sciencesYoung adultLife-span and Life-course StudiesPsychologybusinessta515050104 developmental & child psychology
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