Search results for "modality."

Outdoor Scenes Pixel-wise Semantic Segmentation using Polarimetry and Fully Convolutional Network

2019

International audience; In this paper, we propose a novel method for pixel-wise scene segmentation application using polarimetry. To address the difficulty of detecting highly reflective areas such as water and windows, we use the angle and degree of polarization of these areas, obtained by processing images from a polarimetric camera. A deep learning framework, based on encoder-decoder architecture, is used for the segmentation of regions of interest. Different methods of augmentation have been developed to obtain a sufficient amount of data, while preserving the physical properties of the polarimetric images. Moreover, we introduce a new dataset comprising both RGB and polarimetric images…

Killing of p53-deficient hepatoma cells by parvovirus H-1 and chemotherapeutics requires promyelocytic leukemia protein

2008

To evaluate the synergistic targeting and killing of human hepatocellular carcinoma (HCC) cells lacking p53 by the oncolytic autonomous parvovirus (PV) H-1 and chemotherapeutic agents and its dependence on functional promyelocytic leukemia protein (PML).The role of p53 and PML in regulating cytotoxicity and gene transfer mediated by wild-type (wt) PV H-1 were explored in two pairs of isogenic human hepatoma cell lines with different p53 status. Furthermore, H-1 PV infection was combined with cytostatic drug treatment.While the HCC cells with different p53 status studied were all susceptible to H-1 PV-induced apoptosis, the cytotoxicity of H-1 PV was more pronounced in p53-negative than in p…

Multimodal and Agent-Based Human–Computer Interaction in Cultural Heritage Applications: an Overview

2010

Neural and muscular changes after 4 and 8 weeks of electromyostimulation training

2005

Electromyostimulation (EMS) has been recently used as a modality of resistance training in healthy subjects to enhance maximal voluntary strength (Duchateau 1990, Maffiuletti 2002). The underlying ...

Effects of tumor necrosis factor-alpha on tumor blood flow and hyperthermic treatment.

1989

The impact of recombinant human tumor necrosis factor-alpha (rhTNF-alpha), given alone or in combination with local hyperthermia, on perfusion and growth of a moderately rhTNF-alpha-sensitive rat tumor (DS-carcinosarcoma) was investigated. DS-carcinosarcomas were implanted into the hind foot dorsum of Sprague-Dawley rats. Tumor blood flow (TBF) was measured with the krypton-85 clearance technique. Treatment with either tumor necrosis factor-alpha (0.1-1.0 mg/kg) or hyperthermia (43.3 and 44.3 degrees C, 40 min) can decrease the perfusion of malignant tumors. The TBF reduction was fully established 2 h after rhTNF-alpha injection and lasted for at least 4 h. The application of local hyperthe…

Tumour-growth inhibition by induced hyperglycaemia/hyperlactacidaemia and localized hyperthermia.

1996

The present study was undertaken to exploit pathophysiological properties of solid tumours for a tumour-specific therapy. Experiments were carried out on DS-sarcomas implanted s.c. in the hind foot dorsum of Sprague Dawley rats. Treatment strategies included tumour acidification, lactate accumulation and disturbance of the microcirculation by induced systemic hyperglycaemia/hyperlact-acidaemia (15-25/10 mmol/L; for 60 min) as well as localized hyperthermia (water-bath; 43 degrees C, 30 min.). A special infusion solution was developed for the systemic treatment containing glucose, lactic acid and organic buffer without inorganic ions. Growth kinetics of tumour volume and animal survival were…

The influence of tumor blood flow and microenvironmental factors on the efficacy of radiation, drugs and localized hyperthermia.

1997

It is generally accepted that tumor blood flow, microcirculation, oxygen and nutrient supply, tissue pH distribution, and the bioenergetic status-factors which are usually closely linked and which define the so-called metabolic microenvironment--can markedly influence the therapeutic response of malignant tumors to conventional irradiation, chemotherapy, other nonsurgical treatment modalities, and the cell proliferation activity within tumors. Currently available information on the parameters defining the metabolic micromilieu in human tumors is presented in this review. According to these data, significant variations in these relevant factors are likely to occur between different locations…

Effect of hyperthermia on tumor blood flow.

1984

Differences in blood perfusion rates between tumors and normal tissue can be utilized to selectively heat many solid tumors. Blood flow in normal tissues is considerably increased at temperatures commonly applied during localized hyperthermia. In contrast, tumor blood flow may respond to localized heat typically in two different blood flow patterns: Flow may either decrease continuously with increasing exposure time and/or temperature or flow may exhibit a transient increase followed by a decline. A decrease in blood flow at high thermal doses can be observed in most of the tumors, whereas an increase in flow at low thermal doses seems to occur less frequently. The inhibition of blood flow …

Small Sample Biometric Recognition Based on Palmprint and Face Fusion

2009

Contactless biometrics provide high comfort and hygiene in person recognition. Because of this, such systems are better accepted by the general public. This paper proposes an adaptive, contactless, biometric system which combines two modalities: palmprint and face. The processing chain has been designed to overcome embedded system constraints and small sample set problem: after a palmprint is extracted from a hand image, Gabor filters are applied to both the palmprint and face in order to extract parameters, which are then used for classification. Fusion possibilities are also discussed and tested using a multimodal database of 130 people designed by the authors. High recognition performanc…

A Magnetic Resonance Imaging–Based Prediction Model for Prostate Biopsy Risk Stratification

2018

IMPORTANCE: Multiparametric magnetic resonance imaging (MRI) in conjunction with MRI–transrectal ultrasound (TRUS) fusion-guided biopsies have improved the detection of prostate cancer. It is unclear whether MRI itself adds additional value to multivariable prediction models based on clinical parameters. OBJECTIVE: To determine whether an MRI-based prediction model can reduce unnecessary biopsies in patients with suspected prostate cancer. DESIGN, SETTING, AND PARTICIPANTS: Patients underwent MRI, MRI-TRUS fusion-guided biopsy, and 12-core systematic biopsy in 1 session. The development cohort used to derive the prediction model consisted of 400 patients from 1 institution enrolled between …