Search results for "modality."
showing 10 items of 631 documents
Reproduction beyond cancer: A message of hope for young women
2006
Abstract Objective. Aggressive chemotherapy and radiotherapy or radical oncological surgery in young women with cancer has greatly enhanced these patients' life expectancy, but these treatments often cause infertility or premature ovarian failure due to a massive destruction of the ovarian reserve. The objective of this review is to discuss the effect of the various cancer treatments on fertility and present the various fertility sparing operations and fertility preservation strategies. Method. An extensive survey of the most up-to-date literature was performed. Results. This review discusses the impact of current cancer treatment on fertility potential and the various surgical and assisted…
The addition of interleukin-2 to cyclophosphamide therapy can facilitate tumor growth of B16 melanoma.
1995
The role of interleukin-2 (IL-2) on tumor growth of B16F10 melanoma cells was assessed in two sets of mice with different immune status: normal (immunocompetent) mice and immunodeficient mice. The two sets of animals were treated with cyclophosphamide (CY) or IL-2 alone or with a combined therapy of CY+IL-2. On days 6 and 10 after tumor cell injection, we evaluated the incidence of hepatic B16 melanoma metastases and the percentage of hepatic volume occupied by metastatic tissue. We observed that the CY alone (300 mg/kg, days 3 and 8 post-tumoral inoculation) significantly reduced tumor growth in all treated mice; however, CY proved more effective in normal recipients than in immunodeficien…
Learning cultural literacy through creative practices in schools cultural and multimodal approaches to meaning-making
2022
Introduction: Cultural Literacy and Creativity -- A Sociocultural Approach to Children’s Visual Creations -- Multimodality: Art as a Meaning-Making Process -- Tolerance, Empathy, and Inclusion -- Living Together -- Social Responsibility -- Belonging and Home -- Cultural Literacy During COVID-19 -- Conclusions: Cultural Literacy in Action -- Index. This open access book discusses how cultural literacy can be taught and learned through creative practices. It approaches cultural literacy as a dialogic social process based on learning and gaining knowledge through emphatic, tolerant, and inclusive interaction. The book focuses on meaning-making in children and young people’s visual and multimod…
On the Convergence of Affective and Persuasive Technologies in Computer-Mediated Health-Care Systems
2015
This paper offers a portrayal of how affective computing and persuasive technologies can converge into an effective tool for interfacing biomedical engineering with behavioral sciences and medicine. We describe the characteristics, features, applications, present state of the art, perspectives, and trends of both streams of research. In particular, these streams are analyzed in light of the potential contribution of their convergence for improving computer-mediated health-care systems, by facilitating the modification of patients’ attitudes and behaviors, such as engagement and compliance. We propose a framework for future research in this emerging area, highlighting how key constructs and …
Evidencialitātes izteikšanas līdzekļi latviešu valodā
2014
Anotācija Promocijas darbs „Evidencialitātes izteikšanas līdzekļi latviešu valodā” uzskatāms par pirmo pētījumu, kas par galveno analīzes objektu izvirza evidencialitāti un tās izpausmi latviešu valodā. Evidencialitāte ir semantiska kategorija, kuras galvenā funkcija ir norāde uz informācijas ieguves avotu. Darba mērķis – analizēt evidencialitāti kā semantisku kategoriju, balstoties latviešu valodas materiālā. Promocijas darba teorētiskajā daļā aplūkota evidencialitātes jēdziena izpratne valodniecībā un analīzes iespējas, tās vēsturiskie aizsākumi un attīstība līdz mūsdienām, tipoloģija, tiešas un netiešas informācijas šķīrums un ar to saistītā problemātika, epistēmiskās modalitātes un evid…
Neural and genetic correlates of antidepressant response to sleep deprivation - A functional magnetic resonance imaging study of moral valence decisi…
2007
Context: Total sleep deprivation combined with light therapy causes rapid amelioration of bipolar depression. A polymorphism in the promoter for the serotonin transporter influences both antidepressant response and the structure and function of specific brain areas. Objective: To determine whether antidepressant therapy or the genotype of the serotonin transporter influence the pattern of neural response to a task targeting the depressive biases in information processing (moral valence decision). Design: Before-and-after trial studying the biologic correlates of response to treatment. Setting: University hospital. Patients: Twenty inpatients with bipolar depression. Intervention: Repeated t…
Deliberate use of metaphor and metonymy as mnemonic devices for identification in a non-linguistic modality
2020
Pragmatiniai predikatinių bendraties konstrukcijų aspektai latvių kalboje
2020
Šio straipsnio tikslas – ištirti pragmatinius predikatinės bendraties konstrukcijos latvių kalboje aspektus ir įrodyti, kad šios konstrukcijos turi specifinius pragmatinius ženklus. Priešingai nei tokie pragmatiniai ženklai kaip dalelytės, jungtukai, prieveiksmiai ar prozodija, predikatinės bendraties konstrukcijos latvių kalboje pragmatiškai funkcionuoja kaip atskiras vienetas, t. y., struktūrinis funkcionalumas kyla iš sąsajos, o ne iš atskirų leksinių ar gramatinių elementų. Šios konstrukcijos latvių kalboje žymi marginalinį modalumą, o jų vartojimas yra susijęs su neutraliais, pažymėtais kalbos registrais. Taigi straipsnyje pagrindinis dėmesys skiriamas modalinėms ir laikinoms reikšmėms…
Discourse markers and modality in spoken Catalan: The case of (és) clar
2012
Abstract The present paper illustrates the fuzzy limits between modality markers and discourse markers by analysing the different uses based on the word clar ‘clear’ in oral Catalan. Clar is lexically described as an adjective, but it has developed different functions in various syntactic and pragmatic contexts. In the adverbial and the interjective uses, (es) clar (que) ‘it is clear that’ is a modality marker indicating certainty and shared knowledge. As a conjunction, clar que has developed a concessive meaning (‘but, nevertheless’). When (es) clar acts as a discourse marker (i.e. introducing an utterance) it can be an effective mitigation device used to soften a potentially face-threaten…