Search results for "modality."

The clinical value of PSA increase during intravesical adjuvant therapy for nonmuscle-invasive bladder cancer.

2016

Introduction Prostatic Specific Antigen (PSA), Bacillus Calmette-Guerin (BCG) increase after intravesical BCG has been reported. The need of prostate biopsy in these patients is object of debate. The aim of our study was to evaluate the effect of intravesical therapy on PSA after transurethral resection (TUR) of nonmuscle-invasive bladder cancer (NMIBC). Materials and methods Patients undergoing intravesical chemotherapy or immunotherapy for NMIBC were entered. PSA was measured before TUR, before the first and after the sixth instillation, 30 and 90 days after the last instillation. Patients with PSA ≥4 ng/ml or palpable prostate nodule were excluded. Results Out of 130 patients, 105 were e…

Oral manifestations in SARS-CoV-2 infection

2022

We aimed to evaluate the prevalence of predisposing factors and oral manifestations in SARS-CoV-2 infection. 204 SARS-CoV-2 positive patients were included in the study. Questions regarding the systemic, periodontal health, oral hygiene habits, common symptoms and, oral manifestations of COVID-19 such as oral lesions, and dry mouth were included in the survey. The Visual Analogue Scale (VAS) was used. 47.5% of individuals had various systemic diseases. Dry mouth (44.2%) and oral lesions (22.4%) were the most common oral manifestations in COVID-19 patients. Also, dry mouth had the highest VAS score. The most common oral lesion locations were buccal mucosa (15.2%) and tongue (10.8%). The majo…

"What is the color of English?" : representation of English in the language portraits of Sámi children

2010

Tutkimus on osa Jyväskylän yliopiston kielten laitoksen Pohjoinen monikielisyys - hanketta, jonka tavoitteena on tutkia monikielisyyttä Pohjoiskalotin alueella. Projektissa hyödynnetään sosiolingvistiikkaa, kriittistä diskurs-sintutkimusta ja etnografiaa. Tässä tutkimuksessa esiin nousevat mm. kielentäminen, heteroglossia ja kieli-politiikka. Lähtökohtana ovat henkilökohtaiset kielikokemukset, resurssit ja repertuaarit, ja niiden tutkiminen multimodaalisen aineiston avulla. Erityisen kiinnostuksen kohteena on yksittäisen kielen, englannin, esiin-tyminen aineistossa. Vastaavaa näkökulmaa samantyyppiseen aineistoon ei ole aiemmin hyödynnetty. Tutkimuksen aineisto koostuu neljäntoista 6-12 vuo…

Chemoimmunotherapy with O-FC in previously untreated patients with chronic lymphocytic leukemia

2011

We conducted an international phase 2 trial to evaluate 2 dose levels of ofatumumab, a human CD20 mAb, combined with fludarabine and cyclophosphamide (O-FC) as frontline therapy for chronic lymphocytic leukemia (CLL). Patients with active CLL were randomized to ofatumumab 500 mg (n = 31) or 1000 mg (n = 30) day 1, with fludarabine 25 mg/m2 and cyclophosphamide 250 mg/m2 days 2-4, course 1; days 1-3, courses 2-6; every 4 weeks for 6 courses. The first ofatumumab dose was 300 mg for both cohorts. The median age was 56 years; 13% of patients had a 17p deletion; 64% had β2-microglobulin > 3.5 mg/L. Based on the 1996 National Cancer Institute Working Group (NCI-WG) guidelines, the complete respo…

Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend?

2007

The aim of the present study was to evaluate the effects of a normal-sodium (120 mmol sodium) diet compared with a low-sodium diet (80 mmol sodium) on readmissions for CHF (congestive heart failure) during 180 days of follow-up in compensated patients with CHF. A total of 232 compensated CHF patients (88 female and 144 male; New York Heart Association class II–IV; 55–83 years of age, ejection fraction <35% and serum creatinine <2 mg/dl) were randomized into two groups: group 1 contained 118 patients (45 females and 73 males) receiving a normal-sodium diet plus oral furosemide [250–500 mg, b.i.d. (twice a day)]; and group 2 contained 114 patients (43 females and 71 males) recei…

Hypolipidaemic effects of fenofibrate and fasting in the herbivorous grass carp (Ctenopharyngodon idella) fed a high-fat diet

2008

We investigated whether the hypolipidaemic effect of fenofibrate and fasting observed in most omnivorous mammals may also apply to herbivorous fish. Grass carp (Ctenopharyngodon idella) fed a high-fat (8 %) diet exhibited a marked increase in blood lipids and body fat after 6 weeks. They were then treated with fenofibrate (100 mg/kg body weight) in the same high-fat diet for 2 weeks, followed by fasting for 1 week. Plasma lipid concentration, body fat amount, fatty acid composition, plasma thiobarbituric acid-reactive substances and some parameters related to hepatic fatty acid oxidation were measured, and liver samples were stained for histological examination. Fenofibrate treatment decrea…

A further patient with genitopatellar syndrome requiring multidisciplinary management.

2020

Planting in the pandemic : surveillance on social media

2023

This article looks at interest-driven and informal social media practices that have flourished in the pandemic period and its ensuing renaissance of domesticity. It investigates how tending plants and discussing them on social media serve as a particular site for connecting around loving and taking care of plants. Its focus is on the discursive means with which posters – guided by social media algorithms – rhetorically co-construct a morally acceptable version of a pandemic lifestyle around houseplants. More specifically, drawing on multimodal discourse studies, critical sociolinguistics and work on digital surveillance, it investigates how members of a Finland-based social media site obser…

Signalling and Reception

2002

Communication, a widespread natural phenomenon, occurs in both animals and plants. Signals are evolved traits that transfer information from one individual (the signaller) to another (the receiver); they can occur in any sensory modality. Keywords: cost and benefits; honesty; mimicry; predation; sexual selection

Oxaliplatin and Capecitabine-Based Chemoradiotherapy for Gastric Cancer—An Extended Phase I MARGIT and AIO Trial

2008

Purpose Adjuvant 5-fluorouracil–based chemoradiotherapy has been shown to improve the prognosis of gastric cancer. To optimize these results, in the present study oxaliplatin and capecitabine were used instead of 5-fluorouracil. We sought to determine the maximum tolerated dose and the dose-limiting toxicities (DLT) of these drugs in combination with intensity-modulated radiotherapy. Methods and Materials Patients with resected adenocarcinoma of the stomach or the gastroesophageal junction were included. They received two cycles of induction chemotherapy (oxaliplatin and capecitabine [XelOx] regimen). Using standard Phase I methodology, patients received 45 Gy in 1.8-Gy fractions either in …