Search results for "modelling."
showing 10 items of 1269 documents
Meta-Analysis of Mitochondrial DNA Reveals Several Population Bottlenecks during Worldwide Migrations of Cattle
2014
Several studies have investigated the differentiation of mitochondrial DNA in Eurasian, African and American cattle as well as archaeological bovine material. A global survey of these studies shows that haplogroup distributions are more stable in time than in space. All major migrations of cattle have shifted the haplogroup distributions considerably with a reduction of the number of haplogroups and/or an expansion of haplotypes that are rare or absent in the ancestral populations. The most extreme case is the almost exclusive colonization of Africa by the T1 haplogroup, which is rare in Southwest Asian cattle. In contrast, ancient samples invariably show continuity with present-day cattle …
Pluvial flooding in urban areas: the role of surface drainage efficiency
2018
Pluvial flooding in urban areas may derive from the limited or temporarily reduced efficiency of surface drainage, even when the underlying storm sewers are properly designed. This study focuses on the impact of uncertainties in the operational condition of the surface drainage system on pluvial flood hazard. The flood propagation model FLURB-2D is implemented on a selected study area in the town of Genoa (Italy). Synthetic hyetographs based on the Chicago and bivariate copula methods with suitable return periods are used as input. While simulating the design rainfall, inlet operational conditions are varied stochastically using a Monte Carlo approach. Results confirm that microtopography h…
The Occurrence and Dietary Exposure Assessment of Mycotoxins, Biogenic Amines, and Heavy Metals in Mould-Ripened Blue Cheeses
2020
The occurrence and dietary exposure assessment of 16 mycotoxins, 6 biogenic amines (BAs), and 13 metallic elements in blue-veined cheeses (n = 46) is reported. Co-occurrence of mycophenolic acid (&le
Modelling the presence of disease under spatial misalignment using Bayesian latent Gaussian models.
2015
Modelling patterns of the spatial incidence of diseases using local environmental factors has been a growing problem in the last few years. Geostatistical models have become popular lately because they allow estimating and predicting the underlying disease risk and relating it with possible risk factors. Our approach to these models is based on the fact that the presence/absence of a disease can be expressed with a hierarchical Bayesian spatial model that incorporates the information provided by the geographical and environmental characteristics of the region of interest. Nevertheless, our main interest here is to tackle the misalignment problem arising when information about possible covar…
Adult stem cells, scaffolds for in vivo and in vitro myocardial tissue engineering
2010
Quantification of Different Regulatory Pathways Contributing to Heartbeat Dynamics during Multiple Stimuli: a Proof of the Concept.
2019
The dynamical interplay between brain and heart is mediated by several feedback mechanisms including the central autonomic network and baroreflex loop at a peripheral level, also for a short-term regulation. State of the art focused on the characterization of each regulatory pathway through a single stressor elicitation. However, no studies targeted the actual quantification of different mediating routes leading to the generation of heartbeat dynamics, particularly in case of combined exogenous stimuli. In this study, we propose a new approach based on computational modeling to quantify the contribution of multiple concurrent stimuli in modulating cardiovascular dynamics. In this prelimina…
A heuristic model-based approach for compensating wind effects in ski jumping.
2021
Wind influences the jump length in ski jumping, which raises questions about the fairness. To counteract the wind problem, the International Ski Federation has introduced a wind compensation system in 2009: time-averaged wind velocity components tangential to the landing slope are obtained from several sites along the landing slope, and these data are used in a linear statistical model for estimating the jump length effect of wind. This is considered in the total score of the ski jump. However, it has been shown that the jump length effect estimates can be inaccurate and misleading. The present manuscript introduces an alternative mathematical wind compensation approach that is based on an …
Forward acceleration of the centre of mass during ski skating calculated from force and motion capture data
2016
The purpose of this paper was to present and evaluate a methodology to determine the contribution of bilateral leg and pole thrusts to forward acceleration of the centre of mass (COM) of cross-country skiers from multi-dimensional ground reaction forces and motion capture data. Nine highly skilled cross-country (XC) skiers performed leg skating and V2-alternate skating (V2A) under constant environmental conditions on snow, while ground reaction forces measured from ski bindings and poles and 3D motion with high-speed cameras were captured. COM acceleration determined from 3D motion analyses served as a reference and was compared to the results of the proposed methodology. The obtained value…
A review of runoff generation and soil erosion across scales in semiarid south-eastern Spain
2011
Climate, lithology, soil and especially, intense land use/cover changes, make SE Spain very vulnerable to runoff generation and water erosion leading to loss of nutrients and organic matter and to infrequent but devastating floods, reservoir siltation and mass failures. This susceptibility has led to heavy economic investment and research efforts since the 1980s, making this region a worldwide reference for understanding the hydrology and geomorphology of semiarid ecosystems. Runoff and soil erosion have been intensively studied throughout the last decades in various natural ecosystems as well as in abandoned farmlands. Research has considered a wide range of methods and spatial and tempora…
Tunnel fire active protection: improving ventilation system
2019
Abstract The main aim of this work is to evaluate how the use of an active protection method, consisting in an improved forced longitudinal ventilation system, can determine a positive impact on heat extraction and people evacuation time in a tunnel fire scenario, by considering a case study which simulations are based on a real gallery.