Search results for "modelling."
showing 10 items of 1269 documents
Transportation-cost inequality on path spaces with uniform distance
2008
Abstract Let M be a complete Riemannian manifold and μ the distribution of the diffusion process generated by 1 2 ( Δ + Z ) where Z is a C 1 -vector field. When Ric − ∇ Z is bounded below and Z has, for instance, linear growth, the transportation-cost inequality with respect to the uniform distance is established for μ on the path space over M . A simple example is given to show the optimality of the condition.
Isolation and Characterization of CD276+/HLA-E+ Human Subendocardial Mesenchymal Stem Cells from Chronic Heart Failure Patients: Analysis of Differen…
2012
Mesenchymal stem cells (MSCs) are virtually present in all postnatal organs as well as in perinatal tissues. MSCs can be differentiated toward several mature cytotypes and interestingly hold potentially relevant immunomodulatory features. Myocardial infarction results in severe tissue damage, cardiomyocyte loss, and eventually heart failure. Cellular cardiomyoplasty represents a promising approach for myocardial repair. Clinical trials using MSCs are underway for a number of heart diseases, even if their outcomes are hampered by low long-term improvements and the possible presence of complications related to cellular therapy administration. Therefore, elucidating the presence and role of MS…
Hepatitis C virus prevalence and level of intervention required to achieve the WHO targets for elimination in the European Union by 2030: a modelling…
2017
Background Hepatitis C virus (HCV) is a leading cause of liver-related morbidity and mortality worldwide. In the European Union (EU), treatment and cure of HCV with direct-acting antiviral therapies began in 2014. WHO targets are to achieve a 65% reduction in liver-related deaths, a 90% reduction of new viral hepatitis infections, and 90% of patients with viral hepatitis infections being diagnosed by 2030. This study assessed the prevalence of HCV in the EU and the level of intervention required to achieve WHO targets for HCV elimination. Methods We populated country Markov models for the 28 EU countries through a literature search of PubMed and Embase between Jan 1, 2000, and March 31, 201…
PMT: New analytical framework for automated evaluation of geo-environmental modelling approaches
2019
Geospatial computation, data transformation to a relevant statistical software, and step-wise quantitative performance assessment can be cumbersome, especially when considering that the entire modelling procedure is repeatedly interrupted by several input/output steps, and the self-consistency and self-adaptive response to the modelled data and the features therein are lost while handling the data from different kinds of working environments. To date, an automated and a comprehensive validation system, which includes both the cutoff-dependent and –independent evaluation criteria for spatial modelling approaches, has not yet been developed for GIS based methodologies. This study, for the fir…
Determinants of performance drivers in online food delivery platforms: a dynamic performance management perspective
2022
PurposeThis study aims to demonstrate that the Dynamic Performance Management (DPM) framework, integrating performance management with system dynamics modelling, enables decision-makers to identify sustainable strategies in online food delivery platforms, thereby avoiding company failure.Design/methodology/approachThis study undertakes a multistep methodological approach. After the literature review, a retrospective case study approach was used. To build the DPM framework and the system dynamics simulation model, primary and secondary data were collected and analysed.FindingsThis study by adopting the DPM perspective highlights the critical role performance drivers play to assess the viabil…
Supporting the natural gas supply chain public policies through simulation methods: A dynamic performance management approach
2018
Natural gas is considered the transitional fuel par excellence between fossil and renewable sources, considering its low cost, greater efficiency and lesser impact on the environment. This is the reason why its demand levels have increased worldwide, requiring intervention of public and private stakeholders in order to meet these increments. The participation of diverse interconnected stakeholders (key actors) of the supplier-client form, constitutes a supply chain for natural gas, in which the effects of the application of public policy actions can be analysed in the time, using Dynamic Performance Management DPM methodology. The results of the model show the behaviour of the reserves, pro…
Experimental models of orthodontic tooth movement and their effects on periodontal tissues remodelling.
2021
Made available in DSpace on 2022-04-29T08:31:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Objectives: The present study aimed to compare two different models of orthodontic tooth movement (OTM) in rats by evaluating tooth movement efficiency and periodontal tissues remodelling. Design: Fifteen animals were randomly distributed into 3 groups: control group (untreated); ligature appliance (LA) as experimental OTM using a closed coil spring fixed around maxillary first molar by steel ligature; occlusal appliance (OA) as experimental OTM using a closed coil spring attached on the occlusal surface of the maxillary f…
Late frost damage risk for viticulture under future climate conditions: a case study for the Luxembourgish winegrowing region
2013
Background and Aims Late frosts are a significant risk to grape production in frost-prone viticultural regions. Increasing air temperature because of climate change is likely to advance grape budburst and last frost events in spring. So far, it is unclear whether one trend will be more pronounced than the other, and hence, whether the risk of late frost damage will increase or decrease. The aim of this work was to investigate the future frost risk in the Luxembourgish winegrowing region by assessing the effect of simulated future climate conditions on the timing of budburst and last frost date. Methods and Results Late frost risk was assessed by combining: (i) a phenological model for budbu…
Visión de los maestros en formación sobre los modelos científicos y sus funciones en las ciencias y en su enseñanza
2017
Este estudio examina la visión de 201 futuros maestros sobre los modelos científicos y sus funciones en ciencias y en su enseñanza. Se diseñó e implementó un cuestionario con cinco preguntas abiertas, de las cuales se analizan dos ¿Qué se entiende por modelo científico? y ¿Para qué consideras que son utilizados los modelos en ciencias? ¿Y en la enseñanza de las ciencias? Los resultados mostraron que, aunque un 24,5% reconocen que un modelo científico es una representación simplificada de un fenómeno, encontramos que un 22,8% lo consideran como “método” de trabajo de los científicos En cuanto a sus funciones, un 45,7% identifican los modelos como recursos para explicar, resumir o ejemplifica…
A study of the material in the ATLAS inner detector using secondary hadronic interactions
2011
The ATLAS inner detector is used to reconstruct secondary vertices due to hadronic interactions of primary collision products, so probing the location and amount of material in the inner region of ATLAS. Data collected in 7 TeV pp collisions at the LHC, with a minimum bias trigger, are used for comparisons with simulated events. The reconstructed secondary vertices have spatial resolutions ranging from ~ 200μm to 1 mm. The overall material description in the simulation is validated to within an experimental uncertainty of about 7%. This will lead to a better understanding of the reconstruction of various objects such as tracks, leptons, jets, and missing transverse momentum.