Search results for "modelling"

On critical behaviour in systems of Hamiltonian partial differential equations

2013

Abstract We study the critical behaviour of solutions to weakly dispersive Hamiltonian systems considered as perturbations of elliptic and hyperbolic systems of hydrodynamic type with two components. We argue that near the critical point of gradient catastrophe of the dispersionless system, the solutions to a suitable initial value problem for the perturbed equations are approximately described by particular solutions to the Painlevé-I (P $$_I$$ I ) equation or its fourth-order analogue P $$_I^2$$ I 2 . As concrete examples, we discuss nonlinear Schrödinger equations in the semiclassical limit. A numerical study of these cases provides strong evidence in support of the conjecture.

Meta-Analysis of Mitochondrial DNA Reveals Several Population Bottlenecks during Worldwide Migrations of Cattle

2014

Several studies have investigated the differentiation of mitochondrial DNA in Eurasian, African and American cattle as well as archaeological bovine material. A global survey of these studies shows that haplogroup distributions are more stable in time than in space. All major migrations of cattle have shifted the haplogroup distributions considerably with a reduction of the number of haplogroups and/or an expansion of haplotypes that are rare or absent in the ancestral populations. The most extreme case is the almost exclusive colonization of Africa by the T1 haplogroup, which is rare in Southwest Asian cattle. In contrast, ancient samples invariably show continuity with present-day cattle …

Pluvial flooding in urban areas: the role of surface drainage efficiency

2018

Pluvial flooding in urban areas may derive from the limited or temporarily reduced efficiency of surface drainage, even when the underlying storm sewers are properly designed. This study focuses on the impact of uncertainties in the operational condition of the surface drainage system on pluvial flood hazard. The flood propagation model FLURB-2D is implemented on a selected study area in the town of Genoa (Italy). Synthetic hyetographs based on the Chicago and bivariate copula methods with suitable return periods are used as input. While simulating the design rainfall, inlet operational conditions are varied stochastically using a Monte Carlo approach. Results confirm that microtopography h…

The Occurrence and Dietary Exposure Assessment of Mycotoxins, Biogenic Amines, and Heavy Metals in Mould-Ripened Blue Cheeses

2020

The occurrence and dietary exposure assessment of 16 mycotoxins, 6 biogenic amines (BAs), and 13 metallic elements in blue-veined cheeses (n = 46) is reported. Co-occurrence of mycophenolic acid (&le

Modelling the presence of disease under spatial misalignment using Bayesian latent Gaussian models.

2015

Modelling patterns of the spatial incidence of diseases using local environmental factors has been a growing problem in the last few years. Geostatistical models have become popular lately because they allow estimating and predicting the underlying disease risk and relating it with possible risk factors. Our approach to these models is based on the fact that the presence/absence of a disease can be expressed with a hierarchical Bayesian spatial model that incorporates the information provided by the geographical and environmental characteristics of the region of interest. Nevertheless, our main interest here is to tackle the misalignment problem arising when information about possible covar…

Adult stem cells, scaffolds for in vivo and in vitro myocardial tissue engineering

2010

Quantification of Different Regulatory Pathways Contributing to Heartbeat Dynamics during Multiple Stimuli: a Proof of the Concept.

2019

The dynamical interplay between brain and heart is mediated by several feedback mechanisms including the central autonomic network and baroreflex loop at a peripheral level, also for a short-term regulation. State of the art focused on the characterization of each regulatory pathway through a single stressor elicitation. However, no studies targeted the actual quantification of different mediating routes leading to the generation of heartbeat dynamics, particularly in case of combined exogenous stimuli. In this study, we propose a new approach based on computational modeling to quantify the contribution of multiple concurrent stimuli in modulating cardiovascular dynamics. In this prelimina…

A heuristic model-based approach for compensating wind effects in ski jumping.

2021

Wind influences the jump length in ski jumping, which raises questions about the fairness. To counteract the wind problem, the International Ski Federation has introduced a wind compensation system in 2009: time-averaged wind velocity components tangential to the landing slope are obtained from several sites along the landing slope, and these data are used in a linear statistical model for estimating the jump length effect of wind. This is considered in the total score of the ski jump. However, it has been shown that the jump length effect estimates can be inaccurate and misleading. The present manuscript introduces an alternative mathematical wind compensation approach that is based on an …

Microstructure-process relationship and reactivity at the nanoscale : a molecular dynamics study of Ni, Ni-Al, and Ti-Al metallic systems

2023

The process-microstructure relationship is central in materials science because the microstructure will determine the properties of the materials developed by the processes. In our work, we focused on different metallurgical processes by adopting a description at the atomic scale. This approach allows us to detect the elementary mechanisms that are at the origin of the observed microstructures without having to postulate macroscopic mechanisms or estimate the associated parameters. In this respect, molecular dynamics simulations provide a tool for "in-situ" observation of metallic systems as long as an atomic interaction potential is available. The originality of our approach consists in mo…

Forward acceleration of the centre of mass during ski skating calculated from force and motion capture data

2016

The purpose of this paper was to present and evaluate a methodology to determine the contribution of bilateral leg and pole thrusts to forward acceleration of the centre of mass (COM) of cross-country skiers from multi-dimensional ground reaction forces and motion capture data. Nine highly skilled cross-country (XC) skiers performed leg skating and V2-alternate skating (V2A) under constant environmental conditions on snow, while ground reaction forces measured from ski bindings and poles and 3D motion with high-speed cameras were captured. COM acceleration determined from 3D motion analyses served as a reference and was compared to the results of the proposed methodology. The obtained value…