Search results for "modified"
showing 10 items of 585 documents
Assessment of genetically modified cotton GHB614 × T304‐40 × GHB119 for food and feed uses, import and processing under Regulation (EC) No 1829/2003 …
2018
International audience; The three-event stack cotton GHB614 x T304-40 x GHB119 was produced by conventional crossing to combine three single events, GHB614, T304-40 and GHB119. The genetically modified organisms (GMO) Panel previously assessed the three single cotton events and did not identify safety concerns. No new data on the single cotton events that could lead to modification of the original conclusions on their safety were identified. Based on the molecular, agronomic, phenotypic and compositional characteristics, the combination of the single cotton events and of the newly expressed proteins in the three-event stack cotton did not give rise to food and feed safety concern. The GMO P…
Part C notification (reference C/NL/13/01) from Suntory Holdings Limited for the import, distribution and retailing of carnation SHD-27531-4 cut flow…
2015
Requestor: European CommissionQuestion number: EFSA-Q-2015-00126; The Scientific Panel on Genetically Modified Organisms of the European Food Safety Authority (EFSA GMO Panel) has evaluated the overall safety of genetically modified (GM) carnation SHD-27531-4 cut flowers to be imported into the European Union (EU) for ornamental use. The genetic modification results in the flowers having purple petals. The stability of the new colour trait was observed over multiple vegetative generations. The purple colour of the petals comes from the altered expression levels of anthocyanins, common pigments found in edible fruits and vegetables. Considering the intended use of the GM carnation and the po…
Effects of a structured educational intervention in moderate-to-severe elderly asthmatic subjects.
2019
Background: Adherence to inhaled drugs is linked to patients’ satisfaction with their device, and an incorrect use can negatively affect the outcomes of asthma treatment. We speculated that this is particularly true in elderly asthmatic subjects. Aim: We performed a national pre-post interventional multicentre study, enrolling moderate-to-severe asthmatic subjects aged ≥65 years treated with fixed inhaled combination drugs by dry powder inhaler (DPI) or pressurized metered dose inhaler (pMDI). Adherence and critical errors were evaluated by means of validated questionnaires at first visit (V1) and after 3–6 months (V2). At V1, subjects underwent intensive training on the correct use of the…
Mosaic activating mutations in GNA11 and GNAQ are associated with phakomatosis pigmentovascularis and extensive dermal melanocytosis
2016
Common birthmarks can be an indicator of underlying genetic disease but are often overlooked. Mongolian blue spots (dermal melanocytosis) are usually localized and transient, but they can be extensive, permanent, and associated with extracutaneous abnormalities. Co-occurrence with vascular birthmarks defines a subtype of phakomatosis pigmentovascularis, a group of syndromes associated with neurovascular, ophthalmological, overgrowth, and malignant complications. Here, we discover that extensive dermal melanocytosis and phakomatosis pigmentovascularis are associated with activating mutations in GNA11 and GNAQ, genes that encode Gα subunits of heterotrimeric G proteins. The mutations were det…
A novel alpha-amylase-lipase formulation as anti-staling agent in durum wheat bread
2016
The aim of this work has been to evaluate the anti-staling effect exerted by a novel α-amylase-lipase enzyme formulation on durum wheat bread, in comparison with four different commercial amylase preparations and with control without added enzymes. Bread-making trials were carried out at industrial level. Sliced bread, packed under modified atmosphere, was analyzed for texture profile, moisture content, and water activity during 90 days. Crumb sections were submitted to environmental scanning electron microscopy at the end of the storage period. The α-amylase-lipase enzyme preparation showed synergistic interactions in preventing staling. In particular, bread added of these two enzymes in m…
Cosmologie des théories de gravite modifiées
2017
The study of physical cosmology has reached an exciting era. For the first time in human history, a quantitative model for the formation and the evolution of the Universe exists, which explains a wide range of phenomena and has been tested with incredible accuracy during the last century. Moreover, weare approaching a time when a bounty of high quality cosmological data will be available,allowing us to use cosmology as a tool to test fundamental physics.In particular, as the large-scale structures of the Universe are governed by gravity, cosmology can help us to asses the correctness of Albert Einstein’s general relativity. This idea fueledmost of the work described in this manuscript,in wh…
On the analytical expression of the multicompacton and some exact compact solutions of a nonlinear diffusive Burgers’type equation
2018
International audience; We consider the nonlinear diffusive Burgers' equation as a model equation for signals propagation on the nonlinear electrical transmission line with intersite nonlinearities. By applying the extend sine-cosine method and using an appropriate modification of the Double-Exp function method, we successfully derived on one hand the exact analytical solutions of two types of solitary waves with strictly finite extension or compact support: kinks and pulses, and on the other hand the exact solution for two interacting pulse solitary waves with compact support. These analytical results indicate that the speed of the pulse compactons doesn't depends explicitly on the pulse a…
Simulation study of the effects of intensified crop management in genetically manipulated maize on arable weed flora and associated fauna
2014
International audience; Cultivation of GM crops with herbicide tolerance is mostly associated with changes in crop and weed management, like simplified rotations, simplified tillage and change from selective herbicides to the broadband glyphosate. All of these management practices decrease weed densities in crops and change their composition. Although weeds cause yield loss and harvest problems, they are an important part of arable biodiversity and offer food and habitat for different groups of animals. A simulation study was conducted to analyse indirect effects of intensified cropping in GM maize on biodiversity. The dynamic crop: weed model FlorSys was used to simulate weed densities and…
Assessing the effect of changes of agricultural practices accompanying herbicide-tolerant crops on agricultural biodiversity. A simulation study with…
2014
International audience
How to manage the impact of gene flow on oilseed rape grain quality? Simulation case studies of three contrasted landscapes
2012
Abstract Grain admixture due to gene flow of oilseed rape (OSR) could be economically damaging. Different strategies are currently used or proposed to manage grain quality, ranging from homogenisation at the silo level to tactical decision rules at the field level. The relevance of these general strategies was appraised in the case of genetically modified (GM) OSR in three contrasted regions in Europe: Beauce Blesoise (France), Schleswig-Flensburg (Germany), and Fife (UK). Field patterns, crop allocation and agricultural practices were derived from existing datasets and complementary field surveys. Then a gene flow simulator was used to assess how the local contexts influenced the grain adm…