Search results for "moniz"
showing 10 items of 102 documents
Harmonization of Immune Biomarker Assays for Clinical Studies
2011
Assays that measure a patient's immune response play an increasingly important role in the development of immunotherapies. The inherent complexity of these assays and independent protocol development between laboratories result in high data variability and poor reproducibility. Quality control through harmonization--based on integration of laboratory-specific protocols with standard operating procedures and assay performance benchmarks--is one way to overcome these limitations. Harmonization guidelines can be widely implemented to address assay performance variables. This process enables objective interpretation and comparison of data across clinical trial sites and also facilitates the ide…
Comparative Analysis Between Portugal and Spain
2021
This chapter comparatively analyzes Portugal and Spain in relation to the implementation of the IPSAS-based accounting system as two European continental countries embedded in the Napoleonic administrative tradition and considered “latecomers” in the NPM reforms. It adds knowledge about the differences in the harmonization process and in the operationalization of the new accounting system in these particular contexts. Main findings show that IPSAS and the IFRS-based business accounting system have been important references for the new public sector accounting system in both countries. On the other hand, although Spain is more experienced in operationalizing the new IPSAS-based accounting sy…
An Introduction to the HLanData Project: a Step Forward in the Harmonization of Spatial Information Throughout Europe
2021
Nowadays spatial information is becoming more and more accessible for various purposes due to local, national and European initiatives. This paper is addressed to one such initiative Hlandata, whose purpose is to make a significant step forward in the harmonization and use of land cover (LC) and land use (LU) geographic data and its related data bases over Europe. The project was developed using the best experiences from previous geographic data harmonization activities with the goal of demonstrating the feasibility of European level harmonization of land information related datasets. The three pilot projects “LU-LC Data Analysis System for intermediatelevel users”, “Harmonized and Interope…
La responsabilidad penal de las personas jurídicas. Contexto europeo y solución italiana
2009
1. La responsabilidad penal de las personas jurídicas entre la política criminal europea y la armonización de las soluciones nacionales. - 2. (Des)Orientación doctrinal. - 3. Técnicas de configuración de la responsabilidad penal. - 4. Tres Tipos de responsabilidad. - 5. Unión Europea y armonización de la responsabilidad penal de las personas jurídicas.
Sanctions for Legal Entities in South American and European Systems of Corporate Criminal Liability
2021
The present analysis of sanctions for cases of liability of legal entities for crimes (corporate criminal liability) adopts a two-fold comparative perspective. First, it focuses on the sanctions provided by the laws of those legal systems, in South America, which introduced such liability, especially in the last two decades after the United Nations’ treaties on organized crime and corruption. Then, it continues with a parallel overview of sanctioning choices in those Member States of the European Union which opted for such liability. The analysis highlights similar and different approaches both in the two contexts and within each of them. Overall, a process of “weak harmonization” of sancti…
Ottimizzazione delle prestazioni di una rete stradale tramite l’unificazione del sistema della segnaletica
2010
L’argomento principale di questa tesi si manifesta nella soddisfazione della necessità di armonizzare la segnaletica stradale verticale europea, definendo una strategia di minimizzazione dei costi di sostituzione complessivi della cartellonistica non uniforme, per contribuire a migliorare i livelli di sicurezza e di soddisfacimento dell’utenza dell’infrastruttura stradale. Una maggiore uniformità della segnaletica stradale permetterebbe ai conducenti impegnati nei traffici transfrontalieri su gomma di dover recepire un minor carico di informazioni visive, facendo riferimento ad un numero minore di segnali stradali, in quanto armonizzati con quelli dei loro paesi di provenienza. Altro scopo …
L’unificazione europea della segnaletica stradale
2010
La sicurezza stradale in Europa è un argomento che riguarda in maniera peculiare l’intero territorio dell’Unione. Nell’Europa dei Quindici (EU-15), sono 375 milioni gli utenti della strada, di cui 200 milioni in possesso di patente di guida, che utilizzano veicoli su un totale di 4 milioni di km di strade. Gli incidenti automobilistici sono oggi causa di più di 40.000 morti e 1.700.000 feriti all’anno sul territorio continentale. Il costo, diretto o indiretto di questa ecatombe, stima la Commissione Europea, è di circa 160 miliardi di Euro, ovvero il 2% del PIL. In Italia a causa di incidenti stradali si registrano circa 8.000 morti all’anno. Il 50% di questi incidenti ha come vittime perso…
International Bordetella pertussis assay standardization and harmonization meeting report. Centers for Disease Control and Prevention, Atlanta, Georg…
2009
An international meeting on Bordetella pertussis assay standardization and harmonization was held at the Centers for Disease Control and Prevention (CDC), Atlanta, GA, 19-20 July 2007. The goal of the meeting was to harmonize the immunoassays used for pertussis diagnostics and vaccine evaluation, as agreed upon by academic and government researchers, regulatory authorities, vaccine manufacturers, and the World Health Organization (WHO). The primary objectives were (1) to provide epidemiologic, laboratory, and statistical background for support of global harmonization; (2) to overview the current status of global epidemiology, pathogenesis and immunology of pertussis; (3) to develop a consen…
Mūsdienu latviešu animisma modifikācijas
2015
Mūsdienās īpaša piesaiste dabas pasaulei vairs nav nepieciešama, jo sakrālā pasaule tiek uztverta savādāk, ne vairs kā iztikas nodrošinātāja. Tomēr cilvēkam emocionāla piesaiste ir saglabājusies. Šī pasaule bieži tiek fragmentēta, sakralizējot konkrētu vietu ar dabas objektu elementiem, kuriem tiek piedēvētas enerģētiskas īpašības. Piedēvēt šādas īpašības dabas objektiem ir raksturīgi New Age kustībai. Ietekmējoties no šīs kustības, tradicionālās latviešu animisma idejas tiek sapludinātas ar New Age kustības idejām. Šajā darbā tiek aplūkotas divas svētvietas, kurām tiek piedēvētas enerģētiskas īpašības, kas ir raksturīgi New Age, -Pokaiņi, kas atrodas Dobeles novada Naudītes pagastā un Sokr…