Search results for "monomer"

showing 10 items of 857 documents

PEG-benzofulvene copolymer hydrogels for antibody delivery.

2010

A new amphiphilic copolymer have been synthesized starting from the hydrosoluble polyaspartylhydrazide (PAHy) polymer, by grafting both hydrophilic PEG(2000) chains and hydrophobic palmitic acid (C(16)) moieties on polymer backbone, and the structure of obtained PAHy-PEG(2000)-C(16) copolymer have been characterized by 2D (1)H/(13)C NMR experiments. PAHy-PEG(2000)-C(16) copolymer showed the ability of self-assembling in aqueous media giving a core-shell structure and resulted potentially useful for encapsulating and dissolving hydrophobic drug. The formation of micellar core-shell structure has been investigated by 2D (1)H NMR NOESY experiments. The presence of cross-peaks for protons of C(…

BiocompatibilityCell SurvivalPolymersSurface PropertiesPEG-benzofulvene immunoglobulin delivery hydrogelsimmunoglobulinsPharmaceutical SciencePolyethylene Glycolschemistry.chemical_compoundDrug Delivery SystemsCell Line TumorPolymer chemistryPEG ratioCopolymerHumansantibody deliverybenzofulvene copolymerschemistry.chemical_classificationChemistrytechnology industry and agricultureHydrogelsantibody delivery; benzofulvene copolymers; hydrogels; immunoglobulinsPolymerMacromonomerIndenesSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoImmunoglobulin GDrug deliverySelf-healing hydrogelsbenzofulvene copolymerhydrogelDrug Screening Assays AntitumorRheologyEthylene glycolInternational journal of pharmaceutics
researchProduct

Biotin Induces Tetramerization of a Recombinant Monomeric Avidin

2001

Chicken avidin, a homotetramer that binds four molecules of biotin was converted to a monomeric form by successive mutations of interface residues to alanine. The major contribution to monomer formation was the mutation of two aspartic acid residues, which together account for ten hydrogen bonding interactions at the 1-4 interface. Mutation of these residues, together with the three hydrophobic residues at the 1-3 interface, led to stable monomer formation in the absence of biotin. Upon addition of biotin, the monomeric avidin reassociated to the tetramer, which exhibited properties similar to those of native avidin, with respect to biotin binding, thermostability, and protease resistance. …

Biotin bindingbiologyProtein subunitCell BiologyBiochemistrychemistry.chemical_compoundMonomerchemistryBiotinTetramerBiochemistryBiotinylationbiology.proteinBiophysicsMolecular BiologyAvidinHomotetramerJournal of Biological Chemistry
researchProduct

Study of the Curing Process of DGEBA Epoxy Resin Through Structural Investigation

2015

In this work, a multi-scale approach with different analytical methods is applied to study the curing process and the structural properties of a diglycidyl ether of bisphenol A (DGEBA) epoxy resin. This monomer, thermally cured using 4,4′-diaminodiphenilsulfone (DDS) as hardener, is analyzed after 10, 45, 90, and 120 min of reaction time at 180 °C to obtain information on samples with different cross-linking densities. Samples are also characterized after extraction in acetone in order to obtain structural information on the insoluble parts. For this purpose, differential scanning calorimetry (DSC), dynamic mechanical thermal analysis (DMTA), solid-state nuclear magnetic resonance (ss-NMR),…

Bisphenol AMaterials scienceDiglycidyl etherEpoxy resins solid-state nuclear magnetic resonance (ss-NMR) positron annihilation lifetime spectroscopy (PALS)Polymers and PlasticsOrganic ChemistryEpoxyDynamic mechanical analysisCondensed Matter Physicschemistry.chemical_compoundMonomerDifferential scanning calorimetrychemistrySolid-state nuclear magnetic resonancevisual_artPolymer chemistryMaterials Chemistryvisual_art.visual_art_mediumSettore CHIM/07 - Fondamenti Chimici Delle TecnologiePhysical and Theoretical ChemistryThermal analysis
researchProduct

Design and synthesis of biobased epoxy thermosets from biorenewable resources

2017

International audience; Biobased diepoxy synthons derived from isoeugenol, eugenol or resorcinol (DGE-isoEu, DGE-Eu and DGER, respectively) have been used as epoxy monomers in replacement of the diglycidyl ether of bisphenol A (DGEBA). Their curing with six different biobased anhydride hardeners leads to fully biobased epoxy thermosets. These materials exhibit interesting thermal and mechanical properties comparable to those obtained with conventional petrosourced DGEBA-based epoxy resins cured in similar conditions. In particular, a high Tg in the range of 90–130 °C and instantaneous moduli higher than 4.3 GPa have been recorded. These good performances are very encouraging, making these n…

Bisphenol AMaterials scienceDiglycidyl etherGeneral Chemical EngineeringThermosetting polymer02 engineering and technologyResorcinol010402 general chemistry01 natural sciences[ CHIM ] Chemical SciencesNanoindentationchemistry.chemical_compound[CHIM] Chemical SciencesPolymer chemistry[CHIM]Chemical SciencesComputingMilieux_MISCELLANEOUSCuring (chemistry)Biobased resinsPolymer scienceCuring process[CHIM.MATE]Chemical Sciences/Material chemistryGeneral ChemistryEpoxy021001 nanoscience & nanotechnology0104 chemical sciencesDEGBA alternativeIsoeugenolMonomerchemistryvisual_artvisual_art.visual_art_medium0210 nano-technologyEpoxy-anhydride thermosets
researchProduct

Metal complexes of an amine bisphenol with a thiophene side-arm

2010

Dioxomolybdenum(VI) and oxotungsten(VI) complexes with a new amine bisphenol ligand (H2L) are reported. The ligand which carries a neutral nitrogen atom, two phenolic oxygen atoms and a thiophene side-arm was synthesized by a simple one-pot Mannich reaction. Further reaction with [MoO2(acac)2] yielded a monomeric molybdenum complex [MoO2(L)(MeOH)] (2a) or a dimeric complex [Mo2O2(μ-O)2(L)2] (2b), depending on the reaction conditions. The reaction with a tungsten trisglycolate [W(eg)3] led to the formation of a monomeric compound [WO(eg)(L)] (3). In these complexes, the potentially tetradentate amine bisphenolate dianion coordinates as a tridentate O,N,O donor while the sulfur side-arm donor…

BisphenolLigandchemistry.chemical_elementGeneral ChemistryMedicinal chemistryMetalchemistry.chemical_compoundMonomerchemistryMolybdenumvisual_artThiophenevisual_art.visual_art_mediumOrganic chemistryAmine gas treatingMannich reactionCollection of Czechoslovak Chemical Communications
researchProduct

Dimerization control in the self-assembly behavior of copillar[5]arenes bearing ω-hydroxyalkoxy groups.

2012

Two novel copillar[5]arenes bearing ω-hydroxyalkoxy groups are synthesized and their self-assembly properties are studied by (1)H NMR spectroscopy, specific viscosity, and X-ray measurements. The copillar[5]arene 2b bearing a 6-hydroxyhexyloxy group exhibits a reversible self-assembly behavior, leading to the formation of the self-inclusion monomer and hugging dimers. The reversible self-assembly behavior can be controlled by tuning solvent, temperature, guest, and H-bond interaction. However, the copillar[5]arene 2a bearing a short 4-hydroxybutyloxy group does not show such a self-assembly behavior to the formation of the self-inclusion monomer and hugging dimers.

Bridged-Ring CompoundsModels Molecular1h nmr spectroscopyBearing (mechanical)Molecular StructureIntrinsic viscosityOrganic ChemistryPhotochemistrylaw.inventionSolventCrystallographychemistry.chemical_compoundMonomerchemistryGroup (periodic table)lawAlcoholsBenzene DerivativesDimerizationThe Journal of organic chemistry
researchProduct

Acrylate ester-based monolithic columns for capillary electrochromatography separation of triacylglycerols in vegetable oils

2011

Abstract A simple and reliable method for the evaluation of triacylglycerols (TAGs) in vegetable oils by capillary electrochromatography (CEC) with UV–Vis detection, using octadecyl acrylate (ODA) ester-based monolithic columns, has been developed. The percentages of the porogenic solvents in the polymerization mixture, and the mobile phase composition, were optimized. The optimum monolith was obtained at the following ratios: 40:60% (wt/wt) monomers/porogens, 60:40% (wt/wt) ODA/1,3-butanediol diacrylate and 23:77% (wt/wt) 1,4-butanediol/1-propanol (14 wt% 1,4-butanediol in the polymerization mixture). A satisfactory resolution between TAGs was achieved in less than 12 min with a 65:35 (v/v…

Capillary electrochromatographyAcrylategeographyChromatographygeography.geographical_feature_categoryResolution (mass spectrometry)Organic ChemistryDiscriminant Analysis1-PropanolGeneral MedicineBiochemistryAnalytical Chemistrychemistry.chemical_compoundMonomerVegetable oilAcrylateschemistryPolymerizationCapillary ElectrochromatographyMicroscopy Electron ScanningPlant OilsMonolithButylene GlycolsAmmonium acetateTriglyceridesJournal of Chromatography A
researchProduct

Catechol Acetonide Glycidyl Ether (CAGE): A Functional Epoxide Monomer for Linear and Hyperbranched Multi-Catechol Functional Polyether Architectures

2016

A protected catechol-containing epoxide monomer, catechol acetonide glycidyl ether (CAGE), is introduced. CAGE is conveniently obtained in three steps and enables the incorporation of surface-active catechol moieties into a broad variety of hydrophilic and biocompatible polyether architectures by copolymerization. Via acidic cleavage of the acetal protecting groups, the polymer-attached catechol functionalities are liberated and available for surface attachment or metal complexation. CAGE has been copolymerized with ethylene oxide and glycidol to obtain both linear poly(ethylene glycol) and hyperbranched polyglycerol copolymers, respectively, with multiple surface-adhesive catechol moieties…

CatecholPolymers and PlasticsEthylene oxideOrganic ChemistryAcetalGlycidolEpoxide02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundMonomerchemistryPolymer chemistryMaterials ChemistryCopolymerOrganic chemistry0210 nano-technologyEthylene glycolMacromolecules
researchProduct

Mixed-ligand copper(ii)–sulfonamide complexes: effect of the sulfonamide derivative on DNA binding, DNA cleavage, genotoxicity and anticancer activity

2013

Four ternary complexes, [Cu(L1)2(bipy)] (1) [HL1 = N-(6-chlorobenzo[d]thiazol-2-yl)-4-methylbenzenesulfonamide], [Cu(L2)2(bipy)] (2) [HL2 = N-(benzo[d]thiazol-2-yl)-4-methylbenzenesulfonamide], [Cu(L3)2(bipy)]·1/2H2O (3) [HL3 = N-(5,6-dimethylbenzo[d]thiazol-2-yl)-4-methylbenzenesulfonamide] and [Cu(L4)2(bipy)] (4) [HL4 = N-(5,6-dimethylbenzo[d]thiazol-2-yl)benzenesulfonamide], were prepared and then characterized by X-ray crystallography, spectroscopy and magnetic measurements. Whereas the molecular structure of 1 and 2 consists of a discrete monomeric copper(II) species with a distorted square planar geometry, that of 3 and 4 consists of two independent molecules. In 3, both molecules pre…

Cell SurvivalStereochemistryDNA damageAntineoplastic AgentsApoptosisSaccharomyces cerevisiaeLigandsInorganic ChemistryJurkat Cellschemistry.chemical_compoundCoordination ComplexesHumansMoleculeDNA CleavageCell ProliferationCoordination geometrychemistry.chemical_classificationSulfonamidesDNASquare pyramidal molecular geometryIn vitroSulfonamideCrystallographyMonomerchemistryCaco-2 CellsCopperDNADalton Transactions
researchProduct

Bond strength of selected composite resin-cements to zirconium-oxide ceramic

2012

Objectives: The aim of this study was to evaluate bond strengths of zirconium-oxide (zirconia) ceramic and a selection of different composite resin cements. Study Design: 130 Lava TM cylinders were fabricated. The cylinders were sandblasted with 80 μm aluminium oxide or silica coated with CoJet Sand. Silane, and bonding agent and/or Clearfil Ceramic Primer were applied. One hundred thirty composite cement cylinders, comprising two dual-polymerizing (Variolink II and Panavia F) and two autopolymerizing (Rely X and Multilink) resins were bonded to the ceramic samples. A shear test was conducted, followed by an optical microscopy study to identify the location and type of failure, an elec…

CeramicsMaterials scienceComposite numberSurface treatmentOdontologíaDental bondingComposite ResinsDental Materialschemistry.chemical_compoundCIENCIA DE LOS MATERIALES E INGENIERIA METALURGICABiomaterials and Bioengineering in DentistryMaterials TestingCubic zirconiaCeramicComposite materialGeneral DentistryCementBond strengthShear bond strengthDental BondingSilica coating:CIENCIAS MÉDICAS [UNESCO]SilaneCiencias de la saludResin CementsOtorhinolaryngologychemistryvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumZirconia ceramicsResearch-ArticleSurgeryZirconiumAdhesivePhosphate monomer
researchProduct