Search results for "moral"
showing 10 items of 1471 documents
Prefazione
2012
Il saggio introduttivo approfondisce la teoria della beatitudine strutturata dall'umanesimo di San Francesco di Sales
Simone Weil. L’infinito invocare: bellezza e soprannaturale
2001
Yeast Killer Toxin-Like Candidacidal Ab6 Antibodies Elicited through the Manipulation of the Idiotypic Cascade
2014
A mouse anti-anti-anti-idiotypic (Id) IgM monoclonal antibody (mAb K20, Ab4), functionally mimicking a Wyckerhamomyces anomalus (Pichia anomala) killer toxin (KT) characterized by fungicidal activity against yeasts presenting specific cell wall receptors (KTR) mainly constituted by β-1,3-glucan, was produced from animals presenting anti-KT Abs (Ab3) following immunization with a rat IgM anti-Id KT-like mAb (mAb K10, Ab2). MAb K10 was produced by immunization with a KT-neutralizing mAb (mAb KT4, Ab1) bearing the internal image of KTR. MAb K20, likewise mAb K10, proved to be fungicidal in vitro against KT-sensitive Candida albicans cells, an activity neutralized by mAb KT4, and was capable of…
La “bioetica cattolica” e il mostro di Lochness. In dialogo con Giovanni Fornero
2010
Nucleoprotein-specific nonneutralizing antibodies speed up LCMV elimination independently of complement and FcγR
2013
CD8(+) T cells have an essential role in controlling lymphocytic choriomeningitis virus (LCMV) infection in mice. Here, we examined the contribution of humoral immunity, including nonneutralizing antibodies (Abs), in this infection induced by low virus inoculation doses. Mice with impaired humoral immunity readily terminated infection with the slowly replicating LCMV strain Armstrong but showed delayed virus elimination after inoculation with the faster replicating LCMV strain WE and failed to clear the rapidly replicating LCMV strain Docile, which is in contrast to the results obtained with wild-type mice. Thus, the requirement for adaptive humoral immunity to control the infection was dep…
La transformación del ser humano en la filosofía de Friedrich Nietzsche. Sobre el concepto de "cría" (Züchtung) y su proyección en el pensamiento con…
2021
La tesis examina el concepto de "cría” (Züchtung) en los textos de Friedrich Nietzsche y presenta una interpretación filosófica. Se estudia el surgimiento y desarrollo de este concepto dentro del conjunto de la filosofía de Nietzsche, desde los primeros fragmentos en 1873 y 1875 hasta los últimos usos en las obras de Nietzsche de 1888. Züchtung surge como una herramienta filosófica para el análisis cultural, gracias a la cual Nietzsche investiga y critica cómo diferentes culturas crían distintos tipos de seres humanos. Los valores de una sociedad determinada son la expresión de su constitución fisiológica y sus condiciones de vida. La religión y la moral son consideradas por Nietzsche como …
Tecnologías de secuenciación masiva y PCR digital en la detección de ADN tumoral procedente de tejido y plasma en pacientes de colon localizado
2022
El cáncer de colon se sitúa como uno de los tumores más relevantes a nivel social, con una tasa de entre el 30 y 50% de recaídas tras la resección. Como herramienta de estudio en este tumor, la biopsia líquida se ha abierto paso en diferentes ámbitos, tales como la detección de la heterogeneidad tumoral o la enfermedad mínima residual (EMR). El fundamento de esta estrategia es detectar el ADN tumoral circulante (ctDNA), que se encuentra diluido en el ADN libre circulante (cfDNA), siendo necesario el uso de tecnologías aptas para la detección a frecuencias bajo el 1%. La hipótesis de esta tesis se apoya en variantes somáticas para detectar el ctDNA y definir la heterogeneidad tumoral, la EMR…
L’invention morale et la sagesse pratique. Une lecture de la petite éthique de Paul Ricoeur
2020
La petite éthique ricœurienne bouleverse les présentations classiques des différentes éthiques en raison de la place qu’elle donne à l’imagination morale. Difficilement classable dans le panorama des éthiques contemporaine, le projet ricœurien valorise le pluralisme des traditions morales comme des précompréhensions pratiques tout en donnant à la créativité pratique une place de choix. Cette tension des traditions et de l’imagination éthique donne à sa sagesse pratique un caractère dynamique et heuristique. Montrant la fécondité de cette sagesse à l’heure des sociétés marquées par le pluralisme et la complexité, cet article en déploie la portée pratique. Il retient tout d’abord l’analyse de…
Doping and Moral Disapprovals
2020
This paper explores variance in how people morally disapprove wrongs related to doping. The variance may pertain to what type of moral disapproval a person uses or to what they disapprove of. Our exploration is both conceptual and empirical. Conceptually, we distinguish between four types of moral disapprovals that we call blame, judging blameworthy, condemnation and sadness. We elaborate these four moral phenomena through a conceptual scheme that we call the matrix of moral disapprovals. The matrix is the central conceptual innovation of our paper. It depicts how the four moral disapprovals relate to each other and characterises their typical instances. In the empirical part of the paper, …
Factors related to excessive patellofemoral loading in rearfoot running
2015
Running is recognized as one of the most popular exercise methods. Furthermore, running related injuries have been under the scope for the last few decades. Synchronous function between the segments of the lower limbs is necessary for efficient locomotion. Patellofemoral pain syndrome is a common exercise related syndrome and multifactorial in nature. The purpose of this study was to measure contact forces and frontal plane moments to detect the factors that are associated with atypically high patellofemoral joint loading in rearfoot striking (RFS) running pattern, and moreover, which could possibly contribute to development of the patellofemoral pain syndrome. 39 team sport female athletes…