Search results for "multiple"
showing 10 items of 2678 documents
Contemporary practice and technical aspects in coronary intervention with bioresorbable scaffolds : a European perspective
2015
Aims Next to patient characteristics, the lack of a standardised approach for bioresorbable vascular scaffold (BVS) implantation is perceived as a potential explanation for the heterogeneous results reported so far. To provide some guidance, we sought to find a consensus on the best practices for BVS implantation and management across a broad array of patient and lesion scenarios. Methods and results Fourteen European centres with a high volume of BVS procedures combined their efforts in an informal collaboration. To get the most objective snapshot of different practices among the participating centres, a survey with 45 multiple choice questions was prepared and conducted. The results of th…
Congenital secretory diarrhoea caused by activating germline mutations in GUCY2C
2016
Objective Congenital sodium diarrhoea (CSD) refers to a form of secretory diarrhoea with intrauterine onset and high faecal losses of sodium without congenital malformations. The molecular basis for CSD remains unknown. We clinically characterised a cohort of infants with CSD and set out to identify disease-causing mutations by genome-wide genetic testing. Design We performed whole-exome sequencing and chromosomal microarray analyses in 4 unrelated patients, followed by confirmatory Sanger sequencing of the likely disease-causing mutations in patients and in their family members, followed by functional studies. Results We identified novel de novo missense mutations in GUCY2C, the gene encod…
Wavelength-compensated time-sequential multiplexed color joint transform correlator
2010
We report a wavelength-compensated three-channel (RGB) joint transform correlator (JTC) for color pattern recognition using a ferroelectric liquid-crystal spatial light modulator (SLM) operating in binary pure phase modulation. We apply a previously reported time-multiplexing technique useful in creating wavelength-compensated diffraction patterns, based on the synchronization of properly scaled diffraction masks with the input wavelength selection obtained by applying a rotating RGB color-filter wheel to an Ar-Kr laser. The application of this technique to a JTC architecture permits real-time color object detection. In order to achieve a high light efficiency for the correlation process, w…
Time multiplexing super-resolved imaging without a priori knowledge of the spatial distribution of the encoding structured illumination
2021
Time multiplexing is a super-resolution technique that sacrifices time to overcome the resolution reduction obtained because of diffraction. There are many super resolution methods based on time multiplexing, but all of them require a priori knowledge of the time changing encoding mask, which is projected on the object and used to encode and decode the high-resolution information. In this paper, we present a time multiplexing technique that does not require the a priori knowledge on the projected encoding mask. First, the theoretical concept of the technique is demonstrated; then, numerical simulations and experimental results are presented.
Degree of coherence: a lensless measuring technique.
2009
We present a technique for measuring the degree of coherence that is based on the self-imaging phenomenon. The technique is lensless, has multiplexing capabilities, and can work with high light throughput. Experimental verifications are given.
Superesolution in digital holographic microscopy
2011
In this contribution, we address with the possibility to overcome the limited resolving power of imaging systems beyond the limit imposed by Abbe's diffraction theory. We first review the mathematical foundations underlying superresolution (SR) from an information theory point of view and then we focus on two multiplexing approaches in digital holographic microscopy (DHM) for achieving SR by synthetic aperture (SA) generation.
Multiplexing THz Vortex Beams With a Single Diffractive 3-D Printed Lens
2019
[EN] We present a novel method for experimentally generating multiplexed THz vortex beams by using a single three-dimensional printed element that combines a set of radially distributed spiral phase plates, and a binary focusing Fresnel lens. With this element, we have experimentally demonstrated that THz multiplexing can be tailored to fit within a small space on an optical bench. Results are presented beside numerical simulations, demonstrating the robust nature of the experimental method.
Joint transform correlator with spatial code division multiplexing.
2006
A joint transform correlator may suffer from overlapping of the zero diffraction order of the output, which does not contain relevant information, and the correlation peaks that appear in the first diffraction orders if objects are not sufficiently separated. Such overlapping significantly reduces the signal-to-noise ratio of the identification process. We propose a novel approach based on code division multiplexing technique in which the contrast of the identification peaks is significantly enhanced. The approach does not include placing the two objects side by side but rather includes code multiplexing them. Moreover, the code division multiplexing technique allows the space-bandwidth pro…
Transverse resolution improvement using rotating-grating time-multiplexing approach
2008
The ability to improve the limited resolving power of optical imaging systems while approaching the theoretical diffraction limit has been an attractive discipline with growing interest over the last years due to its benefits in many applied optics systems. This paper presents a new approach to achieve transverse superresolution in far-field imaging systems, with direct application in both digital microscopy and digital holographic microscopy. Theoretical analysis and computer simulations show the validity of the presented approach.
Cytotoxicity of cardiotonic steroids in sensitive and multidrug-resistant leukemia cells and the link with Na(+)/K(+)-ATPase.
2015
Cardiotonic steroids have long been in clinical use for treatment of heart failure and are now emerging as promising agents in various diseases, especially cancer. Their main target is Na(+)/K(+)-ATPase, a membrane protein involved in cellular ion homeostasis. Na(+)/K(+)-ATPase has been implicated in cancer biology by affecting several cellular events and signaling pathways in both sensitive and drug-resistant cancer cells. Hence, we investigated the cytotoxic activities of 66 cardiotonic steroids and cardiotonic steroid derivatives in sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells. Data were then subjected to quantitative structure-activity relationship analysis (QSA…