Search results for "muta"
showing 10 items of 6895 documents
Free Radicals Mediate Systemic Acquired Resistance
2014
Summary: Systemic acquired resistance (SAR) is a form of resistance that protects plants against a broad spectrum of secondary infections. However, exploiting SAR for the protection of agriculturally important plants warrants a thorough investigation of the mutual interrelationships among the various signals that mediate SAR. Here, we show that nitric oxide (NO) and reactive oxygen species (ROS) serve as inducers of SAR in a concentration-dependent manner. Thus, genetic mutations that either inhibit NO/ROS production or increase NO accumulation (e.g., a mutation in S-nitrosoglutathione reductase [GSNOR]) abrogate SAR. Different ROS function additively to generate the fatty-acid-derived azel…
Phytotoxicity and metabolism of chlortoluron in two wheat varieties
1985
Abstract Varietal susceptibility of winter wheat to chlortoluron, 1-(3-chloro-4-methylphenyl)-3,3 dimethylurea, has been studied in two varieties, Corin (susceptible) and Clement (tolerant). After a 24-hr root absorption of the herbicide, phytotoxicity was estimated from growth measurements. When administered at 12 to 96 μM concentrations, the herbicide reduced the growth of both varieties. A significant selective effect was found at 96 μM. Measurements of chlorophyll fluorescence-induction kinetics allowed to discriminate between the two varieties treated with 12 to 48 μM chlortoluron. The metabolism of chlortoluron was studied following absorption of 24 μM solutions. Both varieties produc…
Experimental Introgression To Evaluate the Impact of Sex Specific Traits on Drosophila melanogaster Incipient Speciation
2019
AbstractSex specific traits are involved in speciation but it is difficult to determine whether their variation initiates or reinforces sexual isolation. In some insects, speciation depends of the rapid change of expression in desaturase genes coding for sex pheromones. Two closely related desaturase genes are involved in Drosophila melanogaster pheromonal communication: desat1 affects both the production and the reception of sex pheromones while desat2 is involved in their production in flies of Zimbabwe populations. There is a strong asymmetric sexual isolation between Zimbabwe populations and all other “Cosmopolitan” populations: Zimbabwe females rarely copulate with Cosmopolitan males w…
Nitric oxide production mediates oligogalacturonide-triggered immunity and resistance to Botrytis cinerea in Arabidopsis thaliana
2012
Nitric oxide (NO) regulates a wide range of plant processes from development to environmental adaptation. In this study, we investigated the production and/or function of NO in Arabidopsis thaliana leaf discs and plants elicited by oligogalacturonides (OGs) and challenged with Botrytis cinerea. We provided evidence that OGs triggered a fast and long lasting NO production which was Ca(2+) dependent and involved nitrate reductase (NR). Accordingly, OGs triggered an increase of both NR activity and transcript accumulation. NO production was also sensitive to the mammalian NO synthase inhibitor L-NAME. Intriguingly, we showed that L-NAME affected NO production by interfering with NR activity, t…
Modulation of copper deficiency responses by diurnal and circadian rhythms in Arabidopsis thaliana
2015
Highlight Cyclic expression of copper transport and the responses to copper deficiency are integrated into the light and circadian–oscillator signalling in plants.
Life history and spatial distribution of the enchytraeid wormCognettia sphagnetorum(Oligochaeta) in metal-polluted soil: Below-ground sink-source pop…
2001
We studied the life history, metal-avoidance behavior, spatial distribution, and population growth of enchytraeid worms (Cognettia sphagnetorum [Oligochaeta]) originating from two sites: one uncontaminated, and another patchily polluted by heavy metals. Effects of patchy soil contamination on populations were studied in microcosms. In uncontaminated soil, worms from the polluted site had lower viability and reduced growth rate as juveniles but higher growth rate as adults compared to worms from the unpolluted site. They were also smaller in size at fragmentation (reproduction). Worms from the polluted site reached a larger population size than worms from the unpolluted site. Hence, worms fr…
Effects of Acifluorfen-methyl on cucumber cotyledons : porphyrin accumulation
1988
Abstract The nitrodiphenyl ether herbicide acifluorfen-methyl and the pyridine derivative LS 82-556 induce porphyrin accumulation in green cucumber cotyledons. When experiments are done with intact plants absorbing the herbicide through the roots, that accumulation is light-dependent. 3-(3,4-Dichlorophenyl)-1,1-dimethylurea (DCMU) which prevents cellular damages under these conditions (M. Matringe and R. Scalla, Pestic. Biochem. Physiol. 26 , 150 (1986), also inhibits porphyrin accumulation. In contrast, when detached cotyledons are cut into pieces and floated on herbicide solutions, porphyrins accumulate in the dark. Accordingly, DCMU does not inhibit porphyrin accumulation or protect the …
In vivoanalysis of the lumenal binding protein (BiP) reveals multiple functions of its ATPase domain
2007
International audience; The endoplasmic reticulum (ER) chaperone binding protein (BiP) binds exposed hydrophobic regions of misfolded proteins. Cycles of ATP hydrolysis and nucleotide exchange on the ATPase domain were shown to regulate the function of the ligand-binding domain in vitro. Here we show that ATPase mutants of BiP with defective ATP-hydrolysis (T46G) or ATP-binding (G235D) caused permanent association with a model ligand, but also interfered with the production of secretory, but not cytosolic, proteins in vivo. Furthermore, the negative effect of BiP(T46G) on secretory protein synthesis was rescued by increased levels of wild-type BiP, whereas the G235D mutation was dominant. U…
Health communication in covid-19 era: Experiences from the italian vaccinarsì network websites
2021
In 2013, in a bid to combat Vaccine Hesitancy (VH) and provide information on vaccines by communicating with the general public and the health community (e.g., healthcare workers and public health operators), the Italian Society of Hygiene and Preventive Medicine (S.It.I.) published the national website “VaccinarSì”. The project was subsequently extended to ten Italian Regions. This led to the creation of the VaccinarSì Network, whose websites are publicly owned. The aim of this work was to present the framework of the websites of the VaccinarSì Network and to analyse user behaviour in the pre-COVID-19-era (dating from each website’s publication until 31 January 2020) and in the COVID-19-er…
Robust link prediction in criminal networks: A case study of the Sicilian Mafia
2020
Abstract Link prediction exercises may prove particularly challenging with noisy and incomplete networks, such as criminal networks. Also, the link prediction effectiveness may vary across different relations within a social group. We address these issues by assessing the performance of different link prediction algorithms on a mafia organization. The analysis relies on an original dataset manually extracted from the judicial documents of operation “Montagna”, conducted by the Italian law enforcement agencies against individuals affiliated with the Sicilian Mafia. To run our analysis, we extracted two networks: one including meetings and one recording telephone calls among suspects, respect…