Search results for "nail"

showing 10 items of 216 documents

Merkel cells in ontogenesis of human nails

1993

Digital skin of human fetuses is known to contain a particularly high concentration of Merkel cells. Using antibodies against the simple epithelial cytokeratins (CK) 18 and 20, which are sensitive and specific Merkel cell markers, we studied immunohistochemically the main adnexal structure of digital skin, the nail anlage, in human fetuses (9-22 weeks of gestation) for the presence of Merkel cells. As early as week 9 some clustered Merkel cells were detected in the early matrix primordium. In specimens of week 12-15, abundant Merkel cells were found in the nail anlagen, particularly in the epithelium of the proximal nail-fold and the dorsal and ventral side of the apex region. In contrast, …

Pathologymedicine.medical_specialtyanimal structuresGestational AgeKeratin-20DermatologyMatrix (biology)BiologyIntermediate Filament ProteinsDermisKeratinmedicineHumansskin and connective tissue diseaseschemistry.chemical_classificationintegumentary systemKeratin 20General MedicineAnatomyImmunohistochemistryNeurosecretory SystemsEpitheliummedicine.anatomical_structureNailschemistryNail (anatomy)KeratinsMerkel cellNail matrixArchives of Dermatological Research
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Idiopathic Acquired Leukonychia in a 34-Year-Old Patient

2009

We present a rare case of a 34-year-old patient with persistent, progressive, acquired leukonychia totalis and partialis. Idiopathic acquired leukonychia is a rare chromatic disorder of the nail not associated with other abnormalities and discernible etiology. Our case report did not link the inheritance of leukonychia with diverse clinical syndromes. To our knowledge, only five cases of idiopathic, acquired, true total leukonychia were found in literature. This case was the sixth patient with asymptomatic idiopathic, white fingernails, and toenails without a hereditary cause.

Pediatricsmedicine.medical_specialtyintegumentary systembusiness.industrylcsh:Rlcsh:MedicineCase ReportGeneral MedicineLeukonychia totalismedicine.diseaseAsymptomaticmedicine.anatomical_structureLeukonychia ungueal plates parakeratosis keratohyaline granules.Rare casemedicineLeukonychiaEtiologyNail (anatomy)Settore MED/35 - Malattie Cutanee E Venereemedicine.symptombusinessCase Reports in Medicine
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Metabolism of phenol in the terrestrial snail Cepaea nemoralis L

1992

1. The metabolism of phenol in the terrestrial snail Cepaea nemoralis was studied after injection into the haemocoel of the dorsolateral foot region. 2. Excreted metabolites, and metabolites extracted from the body, were analysed by h.p.l.c. In addition to phenyl beta-D-glucoside, arbutine (quinol beta-D-glucoside), a new conjugate of phenol, was detected.

PharmacologyPhenolbiologybeta-GlucosidaseHealth Toxicology and MutagenesisSnailsGeneral MedicineSnailMetabolismToxicologybiology.organism_classificationBiochemistrychemistry.chemical_compoundPhenolschemistrybiology.animalGastropodaBotanyCepaeaAnimalsPhenolMolluscaChromatography High Pressure LiquidXenobiotica
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Land Snails as a Diet Diversification Proxy during the Early Upper Palaeolithic in Europe

2014

Despite the ubiquity of terrestrial gastropods in the Late Pleistocene and Holocene archaeological record, it is still unknown when and how this type of invertebrate resource was incorporated into human diets. In this paper, we report the oldest evidence of land snail exploitation as a food resource in Europe dated to 31.3-26.9 ka yr cal BP from the recently discovered site of Cova de la Barriada (eastern Iberian Peninsula). Mono-specific accumulations of large Iberus alonensis land snails (Ferussac 1821) were found in three different archaeological levels in association with combustion structures, along with lithic and faunal assemblages. Using a new analytical protocol based on taphonomic…

PleistoceneScienceArchaeological ExcavationSnailsArchaeological recordSocial SciencesBiologyMalacologyMediterranean BasinArchaeometryGeographical LocationsAnimalsHumansHoloceneNutritionMultidisciplinaryFossilsEcologyQRadiometric DatingRLand snailBiology and Life SciencesPaleontologyBiological EvolutionDietEuropeArchaeologyTaphonomyArchaeological DatingPeople and PlacesPaleoecologyMedicineArchaeobiologyPaleobiologyAurignacianResearch ArticlePLoS ONE
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GENETIC VARIABILITY AND DRIFT LOAD IN POPULATIONS OF AN AQUATIC SNAIL

2004

Population genetic theory predicts that in small populations, random genetic drift will fix and accumulate slightly deleterious mutations, resulting in reduced reproductive output. This genetic load due to random drift (i.e., drift load) can increase the extinction risk of small populations. We studied the relationship between genetic variability (indicator of past population size) and reproductive output in eight isolated, natural populations of the hermaphroditic snail Lymnaea stagnalis. In a common laboratory environment, snails from populations with the lowest genetic variability mature slower and have lower fecundity than snails from genetically more variable populations. This result s…

PopulationSnailsFresh WaterBiologyHost-Parasite InteractionsGenetic driftGenetic variationGeneticsAnimalsGenetic variabilitySexual MaturationeducationFinlandEcology Evolution Behavior and SystematicsPopulation Densityeducation.field_of_studyEcologyPopulation sizeReproductionGenetic DriftGenetic VariationSmall population sizeGenetic loadGenetics PopulationMutational meltdownMutationBody ConstitutionTrematodaGeneral Agricultural and Biological SciencesEvolution
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Weyers acrodental dysostosis in a family.

1984

A four generation family with postaxial polydactyly of hands and feet and dental anomalies is reported. Lower and upper incisors were abnormal in shape and number. Additional findings were prominent ear anthelices, hypoplastic and dysplastic nails and mild shortness of stature. Inheritance was dominant with variable expression. It is proposed that the family presents the syndrome of acrofacial dysostosis described by Weyers in 1952. To differentiate it from other acrofacial dysostoses, we suggest naming the condition acrodental dysostosis.

Postaxial polydactylyMaleDental anomaliesNail dysplasiaWeyers acrodental dysostosisbusiness.industryTooth AbnormalitiesDysostosisAnatomyToesmedicine.diseaseDysostosesPedigreeVariable ExpressionFingersDysplastic nailsGeneticsmedicineHumansAbnormalities MultipleFemalebusinessChildGenetics (clinical)Clinical genetics
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The snail lemma for internal groupoids

2019

Abstract We establish a generalized form both of the Gabriel-Zisman exact sequence associated with a pointed functor between pointed groupoids, and of the Brown exact sequence associated with a fibration of pointed groupoids. Our generalization consists in replacing pointed groupoids with groupoids internal to a pointed regular category with reflexive coequalizers.

Pure mathematicsExact sequenceLemma (mathematics)Internal groupoid Snail lemma Fibration Snake lemmaAlgebra and Number TheoryFunctorMathematics::Operator Algebras010102 general mathematicsFibrationMathematics - Category Theory01 natural sciences18B40 18D35 18G50Settore MAT/02 - AlgebraMathematics::K-Theory and HomologyMathematics::Category Theory0103 physical sciencesFOS: MathematicsCategory Theory (math.CT)Regular category010307 mathematical physics0101 mathematicsMathematics::Symplectic GeometryMathematics
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Bipullbacks of fractions and the snail lemma

2017

Abstract We establish conditions giving the existence of bipullbacks in bicategories of fractions. We apply our results to construct a π 0 - π 1 exact sequence associated with a fractor between groupoids internal to a pointed exact category.

Pure mathematicsLemma (mathematics)Exact sequenceInternal groupoidAlgebra and Number Theory010102 general mathematicsMathematics - Category TheoryBicategory of fraction18B40 18D05 18E35 18G5001 natural sciencesMathematics::Algebraic TopologySettore MAT/02 - AlgebraExact categoryMathematics::K-Theory and HomologyMathematics::Category Theory0103 physical sciencesFOS: MathematicsBipullbackSnail lemmaCategory Theory (math.CT)010307 mathematical physics0101 mathematicsMathematics
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An evaluation of a model ecosystem with DDT

1980

The reproducibility, variability, and reliability of a simple aquatic-terrtestrial model ecosystem experiment was tested with p,p'-DDT. The variation among the model replicates as well as within the units was studied by using hierarchal analysis of variance. the complete budget of the chemical was calculated and a theoretical transport model was constructed. The degradation and accumulation of DDT was followed by gas chromatographic residue analysis, which showed good reproducibility of the experimental design. The degradation of DDT in the model was similar to that found in the field, but the determination of concentration factors was questionable. The material balance tables revealed that…

ReproducibilityResidue (complex analysis)Chemical PhenomenaEcologyChemistryHealth Toxicology and MutagenesisSnailsFishesGeneral MedicineEnvironmentPlantsToxicologyModels BiologicalPollutionDDTChemistryBiodegradation EnvironmentalMaterial balanceEnvironmental chemistryAnimalsEcotoxicologyDegradation (geology)EcosystemArchives of Environmental Contamination and Toxicology
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A global network for the control of snail-borne disease using satellite surveillance and geographic information systems

2001

Abstract At a team residency sponsored by the Rockefeller Foundation in Bellagio, Italy, 10-14 April 2000 an organizational plan was conceived to create a global network of collaborating health workers and earth scientists dedicated to the development of computer-based models that can be used for improved control programs for schistosomiasis and other snail-borne diseases of medical and veterinary importance. The models will be assembled using GIS methods, global climate model data, sensor data from earth observing satellites, disease prevalence data, the distribution and abundance of snail hosts, and digital maps of key environmental factors that affect development and propagation of snail…

Resource (biology)GIS DayGeographic information systemDatabases FactualInternational CooperationVeterinary (miscellaneous)SnailsGlobal HealthEnvironmental protectionGlobal networkAnimalsHumansSchistosomiasisMedicineGeographyDigital mappingbusiness.industryEnvironmental resource managementSatellite CommunicationsData sharingInfectious DiseasesInsect ScienceParasitologyThe InternetEnterprise GISbusinessActa Tropica
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