Search results for "nap"
showing 10 items of 2226 documents
L'impécuniosité de l'une des parties ne rend pas inapplicable la convention d'arbitrage
2018
International audience; (Civ. 1re, 13 juill. 2016, Sté MJA c/ Sté Airbus Hélicoptères, FS- P+B, n° 15-19.389, D. 2016. 1575 ; ibid. 2484, obs. Centre de droit de la concurrence Yves Serra ; ibid. 2589, obs. T. Clay ; Rev. arb. 2016. 859, obs. M. Boucaron-Nardetto)
Targeted rescue of synaptic plasticity improves cognitive decline after severe systemic inflammation
2021
AbstractSepsis-associated encephalopathy (SAE) is a frequent complication in patients with severe systemic infection resulting in acute brain dysfunction and incapacitating long-term sequelae. SAE includes delirium, premature death, post-traumatic stress disorder, and major long-term cognitive impairment. The underlying pathophysiology of SAE is largely unresolved and specific treatment options are missing. We induced the peritoneal contamination and infection (PCI) sepsis model in 769 mice and compared these with 259 control mice. We found that experimental sepsis causes synaptic pathology in the brain characterized by severely disordered synaptic plasticity with reduced long-term potentia…
Using mechanical experiments to study ground stone tool use: Exploring the formation of percussive and grinding wear traces on limestone tools
2021
Ground Stone Tools (GST) have been identified in several Levantine archaeological sites dating to the Middle Paleolithic. These tools, frequently made of limestone, are often interpreted based on their morphology and damage as having been used for knapping flint, and sometimes for breaking animal bones or processing vegetal materials as well. However, the lack of experimental referential collections on limestone is a major obstacle for the identification of diagnostic traces on these types of tools and raw material. In this sense, the understanding of the specific function of these GST and the association between tool types and activity often remains unknown or merely speculative. Recent di…
In cerca di cura
2002
La “Giornata dell’Architettura Moderna” di Napoli in sintesi.
Scheelite-Bearing Metalliferous Sequences of the Peloritani Mountains, Northeastern Sicily (with some Remarks on Tungsten Metallogenesis in the Calab…
1988
The Peloritani Mountains (Northeastern Sicily) are part of a segment of the Hercynian chain recognized in the Calabrian-Peloritan Arc, geotectonically defined by a pre-Hercynian crystalline basement (Aspromonte Nappe + Mandanici Unit) overthrust and overturned on its Paleozoic (Cambro-Ordovician up to Devonian Carboniferous) volcanosedimentary cover. Tungsten (scheelite) and associated polymetallic stratabound ores, more or less intensely affected by the pre-Hercynian and Hercynian tectonometamorphic events, are confined to the pre-Hercynian basement. In particular, the most significant scheelite-tourmaline (arsenopyrite) and scheelite-carbonate-quartz (albite) mineralizations could be cons…
New Contributions toPseudonapomyza(Diptera: Agromyzidae) from Spain: Addition of Three New Species
2010
The genus Pseudonapomyza (Diptera: Agromyzidae) includes the main leafminer pests for monocots. Three new species are described that were captured using Malaise traps in "Tinença de Benifassà", "Font Roja" and "Lagunas de La Mata-Torrevieja" (Spain) Natural Parks: Pseudonapomyza curvata n. sp., P. longitata n. sp., and P. sicicornis n. sp. Systematics. Ecological data are discussed.
Morphological and molecular characterization of three new parastenocarididae (Copepoda: Harpacticoida) from caves in Southern Italy
2020
We describe three new parastenocaridid: Cottarellicaris sanctiangeli Bruno & Cottarelli sp. nov., Stammericaris vincentimariae Bruno & Cottarelli sp. nov. and Proserpinicars specincola Bruno & Cottarelli sp. nov., collected in the pools of five different caves located in Calabria (Southern Italy). We conducted a phylogenetic analysis based on the mitochondrial COI and ribosomal 18S sequences of C. sanctiangeli sp. nov. and S. vincentimariae sp. nov., and of four more species of Stammericaris and one Proserpinicaris available from literature. Based on the molecular study, the specimens of C. sanctiangeli sp. nov. are clearly separated from the species belonging to the closely-rel…
Anaplastic Thyroid Carcinoma: A ceRNA Analysis Pointed to a Crosstalk between SOX2, TP53, and microRNA Biogenesis.
2014
It has been suggested that cancer stem cells (CSC) may play a central role in oncogenesis, especially in undifferentiated tumours. Anaplastic thyroid carcinoma (ATC) has characteristics suggestive of a tumour enriched in CSC. Previous studies suggested that the stem cell factorSOX2has a preeminent hierarchical role in determining the characteristics of stem cells in SW1736 ATC cell line. In detail, silencing SOX2 in SW1736 is able to suppress the expression of the stem markers analysed, strongly sensitizing the line to treatment with chemotherapeutic agents. Therefore, in order to further investigate the role of SOX2 in ATC, a competing endogenous RNA (ceRNA) analysis was conducted in order…
Evidence of positive tectonic inversion in the north-central sector of the Sicily Channel (Central Mediterranean)
2016
In order to unravel the tectonic evolution of the north-central sector of the Sicily Channel (Central Mediterranean), a seismo-stratigraphic analysis of single- and multi-channel seismic reflection profiles has been carried out. This allowed to identify, between 20 and 50 km offshore the central-southern coast of Sicily, a ~80-km-long deformation belt, characterized by a set of WNW–ESE to NW–SE fault segments showing a poly-phasic activity. Within this belt, we observed: i) Miocene normal faults reactivated during Zanclean–Piacenzian time by dextral strike-slip motion, as a consequence of the Africa–Europe convergence; ii) releasing and restraining bend geometries forming well-developed pul…
Involvement of purinergic nerves in the NANC inhibitory junction potentials in pigeon oesophageal smooth muscle.
2004
1. Electrical field stimulation (EFS) (0.5 ms in train of 2-32 Hz for 300 ms) in smooth muscle of pigeon oesophagus, in the presence of atropine (1 microm) and guanethidine (1 microm), elicited an inhibitory response consisting of a transient hyperpolarization (inhibitory junction potential, IJP) associated with muscle relaxation. 2. Sodium nitroprusside (SNP, 100 microm) induced hyperpolarization correlated to mechanical relaxation. 3. The nitric oxide (NO) synthase inhibitor N(omega)-nitro-l-arginine (from 0.1 to 100 microm) caused a concentration-dependent reduction of electromechanical response to EFS indicating a role for NO in this response. 4. Apamin (1 microm) reduced both IJP and r…